Search Results - "Flexeder, Claudia"
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1
Cesarean Delivery and Risk of Childhood Obesity
Published in The Journal of pediatrics (01-05-2014)“…Objective To investigate whether birth by cesarean delivery rather than vaginal delivery is a risk factor for later childhood obesity. Study design Healthy,…”
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2
Activation of immune cell proteasomes in peripheral blood of smokers and COPD patients: implications for therapy
Published in The European respiratory journal (01-03-2022)“…Immune cells contain a specialised type of proteasome, the immunoproteasome, which is required for intracellular protein degradation. Immunoproteasomes are key…”
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3
Higher serum 25(OH)D concentrations are associated with improved FEV1 and FVC in adolescence
Published in The European respiratory journal (01-04-2017)“…Vitamin D plays a role in the development of the immune system and the lung, as well as in airway remodelling. Therefore, this study investigated the…”
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Long-term air pollution exposure and lung function in 15 year-old adolescents living in an urban and rural area in Germany: The GINIplus and LISAplus cohorts
Published in International journal of hygiene and environmental health (01-10-2015)“…The impact of outdoor air pollution exposure on long-term lung development and potential periods of increased lung susceptibility remain unknown. This study…”
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5
Reference values of impulse oscillometric lung function indices in adults of advanced age
Published in PloS one (15-05-2013)“…Impulse oscillometry (IOS) is a non-demanding lung function test. Its diagnostic use may be particularly useful in patients of advanced age with physical or…”
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6
Bayesian semiparametric additive quantile regression
Published in Statistical modelling (01-06-2013)“…Quantile regression provides a convenient framework for analyzing the impact of covariates on the complete conditional distribution of a response variable…”
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Second-hand smoke exposure in adulthood and lower respiratory health during 20 year follow up in the European Community Respiratory Health Survey
Published in Respiratory research (14-02-2019)“…Early life exposure to tobacco smoke has been extensively studied but the role of second-hand smoke (SHS) for new-onset respiratory symptoms and lung function…”
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8
Accelerated epigenetic aging as a risk factor for chronic obstructive pulmonary disease and decreased lung function in two prospective cohort studies
Published in Aging (Albany, NY.) (03-08-2020)“…Chronic obstructive pulmonary disease (COPD) is a frequent diagnosis in older individuals and contributor to global morbidity and mortality. Given the link…”
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Age Dependency of GLI Reference Values Compared with Paediatric Lung Function Data in Two German Studies (GINIplus and LUNOKID)
Published in PloS one (20-07-2016)“…A hallmark of the newly published GLI (Global Lungs Initiative) spirometric reference values is their "all-age" (3-95yr) predictive power, accomplished by…”
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Which early life events or current environmental and lifestyle factors influence lung function in adolescents? - results from the GINIplus & LISAplus studies
Published in Respiratory research (12-07-2017)“…Various factors may affect lung function at different stages in life. Since investigations that simultaneously consider several factors are rare, we examined…”
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11
Blood Immunoproteasome Activity Is Regulated by Sex, Age and in Chronic Inflammatory Diseases: A First Population-Based Study
Published in Cells (Basel, Switzerland) (28-11-2021)“…Dysfunction of the immunoproteasome has been implicated in cardiovascular and pulmonary diseases. Its potential as a biomarker for predicting disease stages,…”
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12
Metabolomics Identifies Novel Blood Biomarkers of Pulmonary Function and COPD in the General Population
Published in Metabolites (01-04-2019)“…Determination of metabolomic signatures of pulmonary function and chronic obstructive pulmonary disease (COPD) in the general population could aid in…”
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13
Effects of air pollution on exhaled nitric oxide in children: Results from the GINIplus and LISAplus studies
Published in International journal of hygiene and environmental health (01-04-2014)“…Most previous studies which have investigated the short-term effects of air pollution on airway inflammation, assessed by an increase of exhaled nitric oxide…”
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14
Relation of lung function and current inhalant allergen-specific immunoglobulin E concentrations in adolescents (GINIplus cohort)
Published in Annals of allergy, asthma, & immunology (01-09-2015)“…Abstract Background The prevalence of allergen sensitization reaches up to 46.6% in 14- to 17-year-old German adolescents. Polysensitization is strongly…”
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15
Green space quality and adolescent mental health: do personality traits matter?
Published in Environmental research (15-04-2022)“…Adolescents, especially females, tend to experience poorer mental health if they are higher in introversion and neuroticism. As a result, they also may have…”
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Changes in sleep duration and sleep difficulties from adolescence to young adulthood and the risk of obesity: Bidirectional evidence in the GINIplus and LISA studies
Published in Sleep medicine (01-01-2023)“…This study aimed to assess the association of changes in sleep behaviors from adolescence to young adulthood with the risk of overweight/obesity, and the…”
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Air pollution exposure and lung function in children: the ESCAPE project
Published in Environmental health perspectives (01-11-2013)“…There is evidence for adverse effects of outdoor air pollution on lung function of children. Quantitative summaries of the effects of air pollution on lung…”
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18
Body mass index and the incidence of asthma in children
Published in Current opinion in allergy and clinical immunology (01-04-2014)“…PURPOSE OF REVIEWWhen evaluating the causal link between obesity and the development of asthma in children, prospective cohort studies are essential. The…”
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Early growth characteristics and the risk of reduced lung function and asthma: A meta-analysis of 25,000 children
Published in Journal of allergy and clinical immunology (01-04-2016)“…Background Children born preterm or with a small size for gestational age are at increased risk for childhood asthma. Objective We sought to assess the…”
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Association between objectively assessed physical activity and sleep quality in adolescence. Results from the GINIplus and LISA studies
Published in Sleep medicine (01-08-2020)“…Population-based studies on the association of objectively assessed physical activity (PA) with sleep among adolescents are rare. We examined this association…”
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