Search Results - "Fleury, Maud"
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Long-lasting inhibitory effects of fetal liver mesenchymal stem cells on T-lymphocyte proliferation
Published in PloS one (19-05-2011)“…Human bone marrow mesenchymal stem cells (BM-MSC) are multipotent progenitor cells that have transient immunomodulatory properties on Natural Killer (NK)…”
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In Vivo Repopulating Activity Emerges at the Onset of Hematopoietic Specification during Embryonic Stem Cell Differentiation
Published in Stem cell reports (10-03-2015)“…The generation of in vivo repopulating hematopoietic cells from in vitro differentiating embryonic stem cells has remained a long-standing challenge. To date,…”
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Monoclonal antibody 1.6.1 against human MPL receptor allows HSC enrichment of CB and BM CD34+ CD38− populations
Published in Experimental hematology (01-04-2016)“…Thrombopoietin (TPO) and its receptor Mpl (CD110) play a crucial role in the regulation of hematopoietic stem cells (HSCs). Functional study of Mpl-expressing…”
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Dual role of Mpl receptor during the establishment of definitive hematopoiesis
Published in Development (Cambridge) (15-08-2007)“…Cytokine signaling pathways are important in promoting hematopoietic stem cell (HSC) self-renewal, proliferation and differentiation. Mpl receptor and its…”
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FOXF1 inhibits hematopoietic lineage commitment during early mesoderm specification
Published in Development (Cambridge) (01-10-2015)“…The molecular mechanisms orchestrating early mesoderm specification are still poorly understood. In particular, how alternate cell fate decisions are regulated…”
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VE-cadherin expression allows identification of a new class of hematopoietic stem cells within human embryonic liver
Published in Blood (25-11-2010)“…Edification of the human hematopoietic system during development is characterized by the production of waves of hematopoietic cells separated in time, formed…”
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Mpl receptor defect leads to earlier appearance of hematopoietic cells/hematopoietic stem cells in the Aorta-Gonad-Mesonephros region, with increased apoptosis
Published in The International journal of developmental biology (2010)“…In a previous study, we underlined the functional role of the TPO receptor, Mpl, in the establishment of definitive mouse hematopoiesis, by demonstrating that…”
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siRNA Knock down of MPL Receptor in Mouse Hematopoietic Progenitors
Published in Blood (16-11-2005)“…We recently showed that the expression of the thrombopoietin (TPO) receptor, MPL, could have different impacts on the generation and the expansion of…”
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