Search Results - "Fletcher, Matthew D"
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Biosynthesis of the Marine Cyanobacterial Metabolite Barbamide. 1. Origin of the Trichloromethyl Group
Published in Journal of the American Chemical Society (22-07-1998)“…A remarkable structural feature of many marine-derived natural products is the covalent inclusion of chlorine and bromine atoms. A majority of these halogen…”
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2
Iodocyclisations reactions of Boc- and Cbz-protected N-allylguanidines
Published in Tetrahedron (22-07-2014)“…The cyclisation of mono-protected and bis-protected guanidines 8a–j under standard iodocyclisation conditions (I2/K2CO3) gave the guanidine heterocycles 9–25…”
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3
Iodocyclisation and rearrangement reactions of mono-protected allyl substituted guanidines
Published in Tetrahedron letters (29-12-2010)“…The iodocyclisation of a range N-allyl and N-homoallylguanidines using I 2/K 2CO 3 has been found to lead to a series of novel heterocycles which undergo…”
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4
Cyclisation reactions of bis-protected guanidines
Published in Tetrahedron letters (2008)“…The cyclisation of N-allyl- and N-homoallylguanidines using DMDO or I 2/K 2CO 2 leading to novel heterocycles is reported…”
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5
Meet the Molecules in Chocolate: Informal Opportunities for Building Thematic Molecular Models with Children
Published in Journal of chemical education (01-10-2008)“…We describe the development and use of a molecular model building activity with a chocolate theme, suitable for a public presentation of chemistry through…”
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Gentamicin concentrations in diagnostic aspirates from 25 patients with hip and knee arthroplasties
Published in Acta orthopaedica Scandinavica (01-04-2004)“…There is little information on long-term release of antibiotics from impregnated bone cement. We assayed joint fluids obtained for diagnostic purposes from 25…”
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7
Synthesis of highly-functionalised pyridines via hetero-Diels–Alder methodology: reaction of 3-siloxy-1-aza-1,3-butadienes with electron deficient acetylenes
Published in Tetrahedron (05-06-2006)“…The hetero-Diels–Alder reaction between 1-aza-3-siloxy-1,3-butadienes and electron deficient acetylenes is described. The reactivity of a range of…”
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The [1,2]-thio-Wittig rearrangement: evidence for a radical mechanism and its suppression
Published in Tetrahedron letters (06-11-2006)“…The lithium enolate formed from methyl S-trityl mercaptoacetate can be C-alkylated in high yield at or below −40 °C, but at higher temperatures the…”
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