Search Results - "Fletcher, Carl"

Rapid identification of seized controlled substances and related compounds by tandem mass spectrometry without chromatography by Fletcher, Carl M., Sleeman, Richard

“…Rationale This study demonstrates the capability of using tandem mass spectrometry (MS/MS) for the identification of substances of abuse and related compounds…”
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Steady-State Pharmacokinetics of Abacavir in Plasma and Intracellular Carbovir Triphosphate following Administration of Abacavir at 600 Milligrams Once Daily and 300 Milligrams Twice Daily in Human Immunodeficiency Virus-Infected Subjects by MOYLE, Graeme, BOFFITO, Marta, FLETCHER, Carl, HIGGS, Chris, HAY, Phillip E, SONG, Ivy H, YU LOU, YUEN, Geoffrey J, MIN, Sherene S, GUERINI, Elena M

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Boosted saquinavir hard gel formulation exposure in HIV-infected subjects: ritonavir 100 mg once daily versus twice daily by Boffito, Marta, Maitland, Desmond, Dickinson, Laura, Back, David, Hill, Andrew, Fletcher, Carl, Moyle, Graeme, Nelson, Mark, Gazzard, Brian, Pozniak, Anton

“…Objectives: The amount of ritonavir needed to enhance saquinavir hard gel (hg) plasma concentrations is unclear. Reduced ritonavir dosing may help to reduce…”
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The impact of a combined mentalisation-based therapy and therapeutic community programme for adolescents with borderline personality disorder traits on service utilisation in Western Australia by Robinson Lake, Jemima, Bear, Natasha, Fletcher, Carl, Pace, Giulia, Salmin, Ivan, Brealey, Georgia

“…This study assessed the effect of a mentalisation-based therapy (MBT) treatment programme on the utilisation of Western Australian public hospitals for mental…”
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Explosive detection using a novel dielectric barrier discharge ionisation source for mass spectrometry by Fletcher, Carl, Sleeman, Richard, Luke, John, Luke, Peter, Bradley, James W.

“…The detection of explosives is of great importance, as is the need for sensitive, reliable techniques that require little or no sample preparation and short…”
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Explosive detection using a novel dielectric barrier discharge ionisation source for mass spectrometry by Fletcher, Carl, Sleeman, Richard, Luke, John, Luke, Peter, Bradley, James W.

“…The detection of explosives is of crucial importance in applications such as forensic science, environmental monitoring, aviation security, and overall public…”
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Development of Atmospheric Pressure Plasma Based Desorption-Ionisation Sources for Mass Spectrometry by Fletcher, Carl

“…Ambient ionisation mass spectrometry is a rapidly increasing field, largely dominated by ambient ionisation sources that are dependent upon plasma formation…”
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Switching to dolutegravir plus rilpivirine versus maintaining current antiretroviral therapy regimen in virologically suppressed people with HIV-1 and the Lys103Asn (K103N) mutation: 48-week results from a randomised, open-label pilot clinical trial by Moyle, Graeme, Assoumou, Lambert, de Castro, Nathalie, Post, Frank A, Curran, Adrian, Rusconi, Stefano, De Wit, Stephane, Stephan, Christoph, Raffi, François, Johnson, Margaret, Masia, Mar, Vera, Jaime, Jones, Bryn, Grove, Richard, Fletcher, Carl, Duffy, Annie, Morris, Kellie, Pozniak, Anton, Moyle, Graeme, de Castro, Nathalie, Post, Frank, Curran, Adrian, Rusconi, Stefano, De Wit, Stephane, Stephan, Christoph, Raffi, François, Johnson, Margaret, Masia, Mar, Vera, Jaime, Winston, Alan, Kegg, Stephen, Waters, Laura, Orkin, Chole, Ustianowski, Andrew, Reeves, Iain, Leen, Clifford, Perry, Meghan, Portilla, Joaquin, Blanco, Jose Luis, Montejaro, Rocio, Domingo, Pere, Molina, Jean Michel, Katlama, Christine, Morlat, Philippe, Kenyon, Christopher, Puoti, Massimo, Rizzardini, Giuliano, Castagna, Antonella, Castelli, Francesco, Giacomelli, Andrea, Rockstroh, Jürgen, Esser, Stefan, Hoffmann, Christian, Mallon, Patrick

“…The combination of dolutegravir plus rilpivirine has been studied in people with virologically suppressed HIV with no previous history of treatment failure or…”
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Clinical outcomes by supplemental oxygen use in remdesivir-treated, hospitalised adults with COVID-19 by Arber, Nadir, Shah, Pallav L., Assoumou, Lambert, Rokx, Casper, De Castro, Nathalie, Bakhai, Ameet, Soriano Viladomiu, Alex, Mateu, Lourdes, Lumbreras, Carlos, Estrada, Vicente, Curran, Adrian, Sellier, Pierre-Olivier, Duffy, Annie, Fletcher, Carl, Mozaffari, Essy, Haubrich, Richard, Hodgkins, Paul, Pozniak, Anton, Raffi, Francois

“…•Real-world study of hospitalised COVID-19 patients treated with remdesivir.•Higher mortality and longer hospitalisation in HFO compared to LFO and NSO…”
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536. Clinical Outcomes of Hospitalized COVID-19 Patients Treated with Remdesivir-NEAT ID 909REM Study by Raffi, François, Arber, Nadir, Rokx, Casper, Assoumou, Lambert, Shah, Pallav L, De Castro, Nathalie, Bakhai, Ameet, Soriano, Alex, Mateu, Lourdes, Lumbreras, Carlos, Estrada, Vicente, Curran, Adrian, Sellier, Pierre-Olivier, Duffy, Annie, Fletcher, Carl, Mozaffari, Essy, Haubrich, Richard, Hodgkins, Paul, Pozniak, Anton

“…Abstract Background There are few real-world data on the use of remdesivir (RDV) looking at timing of initiation in relation to symptom onset and severity of…”
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Pharmacokinetics and antiretroviral response to darunavir/ritonavir and etravirine combination in patients with high-level viral resistance by BOFFITO, Marta, WINSTON, Alan, GAZZARD, Brian, JACKSON, Akil, FLETCHER, Carl, POZNIAK, Anton, NELSON, Mark, MOYLE, Graeme, TOLOWINSKA, Izabela, HOETELMANS, Richard, MIRALLES, Diego

“…Cumulative antiretroviral exposure can result in multiclass HIV drug resistance. Experimental antiretroviral agents offer limited therapeutic benefit as…”
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Investigation of low-dose ritonavir on human peripheral blood mononuclear cells using gene expression whole genome microarrays by Yilmaz, Saliha, Boffito, Marta, Collot-Teixeira, Sophie, De Lorenzo, Ferruccio, Waters, Laura, Fletcher, Carl, Back, David, Pozniak, Anton, Gazzard, Brian, McGregor, John Louis

“…Ritonavir is a protease inhibitor associated with metabolic abnormalities and cardiovascular disease. We have investigated the effects of low-dose ritonavir…”
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Effect of omeprazole on the pharmacokinetics of saquinavir-500 mg formulation with ritonavir in healthy male and female volunteers by WINSTON, Alan, BACK, David, FLETCHER, Carl, ROBINSON, Lesley, UNSWORTH, Jennifer, TOLOWINSKA, Izabela, SCHUTZ, Malte, POZNIAK, Anton L, GAZZARD, Brian, BOIFITO, Marta

“…Recent studies have described reduced absorption of certain protease inhibitors when administered with agents known to increase gastric pH. No clinically…”
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Steady-State Pharmacokinetics of Saquinavir Hard-Gel/Ritonavir/Fosamprenavir in HIV-1–Infected Patients by Boffito, Marta, Dickinson, Laura, Hill, Andrew, Back, David, Moyle, Graeme, Nelson, Mark, Higgs, Chris, Fletcher, Carl, Gazzard, Brian, Pozniak, Anton

“…BACKGROUND:In vitro synergy and complementary resistance profiles provide a strong rationale for combining fosamprenavir with saquinavir as part of a potent…”
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Dose escalation or immediate full dose when switching from efavirenz to nevirapine-based highly active antiretroviral therapy in HIV-1-infected individuals? by WINSTON, Alan, POZNIAK, Anton, SMITH, Nicola, FLETCHER, Carl, MANDALIA, Sundhiya, PARMAR, Darmishta, GIBBONS, Sarah, BACK, David, GAZZARD, Brian, NELSON, Mark

“…Efavirenz induces the metabolism of co-administered drugs through the induction of CYP A4. It is often necessary to switch fron efavirenz to nevirapine because…”
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Pharmacokinetics of saquinavir hard-gel/ritonavir and atazanavir when combined once daily in HIV Type 1-infected individuals administered different atazanavir doses by Boffito, Marta, Maitland, Desmond, Dickinson, Laura, Back, David, Hill, Andrew, Fletcher, Carl, Moyle, Graeme, Nelson, Mark, Gazzard, Brian, Pozniak, Anton

“…The pharmacokinetics and short-term safety of atazanavir 150 and 200 mg, when coadministered with saquinavir/ritonavir 1600/100 mg once daily, were evaluated…”
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New Disclosure Requirement in Effect for Contracts with W.Va. Agencies by Fletcher, Carl, Bailey, Gene

“…The disclosure requirements are part of a broad effort to prohibit nepotism, increase transparency in public contracting and, ultimately, rebuild trust in…”
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Pharmacokinetics of once-daily saquinavir/ritonavir in HIV-infected subjects: comparison with the standard twice-daily regimen by BOFFITO, Marta, DICKINSON, Laura, POZNIAK, Anton, HILL, Andrew, BACK, David, MOYLE, Graeme, NELSON, Mark, HIGGS, Chris, FLETCHER, Carl, MANDALIA, Sundhiya, GAZZARD, Brian

“…To evaluate the steady-state pharmacokinetics and safety of two once-daily saquinavir/ritonavir (SQV/RTV) regimens, 1600/100 and 2000/100 mg, in HIV-positive…”
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A training program for lay evangelists in the principles of communication by Fletcher, Carl

“…Problem. Many dedicated lay people who are involved in evangelism often lack good communication skills. Consequently their effectiveness is impaired and the…”
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Alternative piezoresistor designs for maximizing cantilever sensitivity by Fletcher, Patrick Carl

“…Over the last 15 years, researchers have explored the use of piezoresistive microcantilevers/resonators as gas sensors because of their relative ease in…”
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