The effects of wine consumption on cardiovascular disease and associated risk factors: a narrative review

The effects of wine consumption on cardiovascular disease and associated risk factors: a narrative review

Accumulating evidence suggests that regular moderate consumption of wine can positively influence risk factors associated with cardiovascular health. These effects are often attributed to grape and wine-derived phenolic compounds and their effects on risk factors such as atherosclerosis, for which m...

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Bibliographic Details
Published in:OENO one Vol. 52; no. 1; pp. 67 - 79
Main Authors: Teissedre, Pierre-Louis, Stockley, Creina, Boban, Mladen, Ruf, Jean-Claude, Ortiz Alba, Marta, Gambert, Philippe, Flesh, Markus
Format: Journal Article
Language:English
Published: International Viticulture and Enology Society (IVES) 01-01-2018
International Viticulture and Enology Society
Subjects:
cardiovascular diseases
Chemical and Process Engineering
consumption
Engineering Sciences
ethanol
Food engineering
Life Sciences
pathophysiological mechanisms
polyphenols
wine
pathophysiological mechanisms
polyphenols
consumption
cardiovascular diseases
ethanol
wine
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Summary:Accumulating evidence suggests that regular moderate consumption of wine can positively influence risk factors associated with cardiovascular health. These effects are often attributed to grape and wine-derived phenolic compounds and their effects on risk factors such as atherosclerosis, for which mechanisms have been clearly identified, such as a decrease in the oxidation of LDL-cholesterol and reduction of oxidative stress, and an increase in nitric oxide and related restoration of endothelial function. In addition, the ethanol component of wine increases HDL-cholesterol, inhibits platelet aggregation, promotes fibrinolysis and reduces systemic inflammation. Scientific research needs to be conducted, however, before we can begin to provide science-based dietary recommendations, although there is sufficient evidence to generally recommend consuming food sources rich in bioactive compounds such as wine in moderation. This narrative review examines published evidence on the cardioprotective effects associated with wine-derived compounds, with a primary focus on the development and progression of atherosclerosis and thrombosis.
ISSN:2494-1271
2494-1271
DOI:10.20870/oeno-one.2018.52.1.2129