Search Results - "Flesch, B. K."

HLA Class II Haplotypes Differentiate Between the Adult Autoimmune Polyglandular Syndrome Types II and III by Flesch, B. K, Matheis, N, Alt, T, Weinstock, C, Bux, J, Kahaly, G. J

“…Background: Genetics of the adult autoimmune polyglandular syndrome (APS) is poorly understood. Aim: The aim of this study was to gain further insight into the…”
Get full text

Post‐transfusion purpura in a patient with HPA‐1a and GPIa/IIa antibodies by Woelke, C., Eichler, P., Washington, G., Flesch, B. K.

“…Post‐transfusion purpura is a rare bleeding disorder characterized by severe and sudden thrombocytopenia within 3–12 days after blood transfusion. Typically,…”
Get full text

HLA Class II Differentiates Between Thyroid and Polyglandular Autoimmunity by Barkia Beradhi, S, Flesch, B K, Hansen, M P, Matheis, N, Kahaly, G J

“…The HLA class II genes are susceptibility genes for autoimmune endocrine diseases; however, scarce data are available pertaining to the determinants of genetic…”
Get more information

Rapid typing of the human Fc gamma receptor IIA polymorphism by polymerase chain reaction amplification with allele-specific primers by Flesch, B.K., Bauer, F., Neppert, J.

“…BACKGROUND: The human Fc gamma receptor IIa (Fc gamma RIIa) is expressed in two polymorphic forms, Fc gamma RIIa‐H131 and Fc gamma RIIa‐R131, that differ by…”
Get full text

Inhibition of monocyte and polymorphonuclear granulocyte immune phagocytosis by monoclonal antibodies specific for FcγRI, II and III by FLESCH, B. K, ACHTERT, G, NEPPERT, J

“…We tested two Fc gamma receptor I (Fc gamma RI); six Fc gamma RII; and six Fc gamma RIII-specific monoclonal antibodies (mAb) for their capacity to inhibit…”
Get full text

Fcγ receptor-mediated immune phagocytosis depends on the class of FcγR and on the immunoglobulin-coated target cell by Flesch, B. K., Vöge, K., Henrichs, T., Neppert, J.

“…Background and Objectives Three human Fcγ receptors (FcγR) are known to mediate immune phagocytosis. A variety of different phagocytic assays have been…”
Get full text

Evidence for gene recombination in FCGR3 gene variants by Blum, K. S., Tong, Y., Siebert, R., Marget, M., Humpe, A., Neppert, J., Flesch, B. K.

“…Background and Objectives  The genes encoding the Fcγ receptors (FcγR) IIIa and IIIb (FCGR3A and FCGR3B) are clustered on chromosome 1 band q23–24 and exhibit…”
Get full text

TRALI - new challenges for histocompatibility and immunogenetics in transfusion medicine by Flesch, B. K., Petershofen, E. K., Bux, J.

“…Antibodies against human leukocyte antigens (HLAs) have long been associated with transfusion‐related acute lung injury (TRALI). In contrast to febrile…”
Get full text

The NA"null" phenotype of a young man is caused by an FcγRIIIB gene deficiency while the products of the neighboring FcγRIIA and FcγRIIIA genes are present by Flesch, B. K., Achtert, G., Bauer, F., Neppert, J.

“…A 27-year-old man with an allergy to house dust mites was found to lack the Fc gamma RIIIb on his neutrophils. Cell surface marker and PCR techniques were used…”
Get full text

Effects of ganglioside (Cronassial) treatment on MHC Ia antigen expression and allograft survival of pancreatic islets in diabetic rats by BRETZEL, R. G, FLESCH, B. K, WILLIG, J, WOEHRLE, M, FEDERLIN, K

“…Streptozotocin-diabetic BdII rats were treated daily with 20 mg/kg body weight gangliosides for ten days beginning two days before transplantation. This…”
Get full text

Islet transplantation in experimental diabetes of the rat. XIII. Cryopreservation reduces MHC class II but not class I antigens of rat pancreatic islets by Flesch, B K, Entenmann, H, Milde, K, Bretzel, R G, Federlin, K

“…Pretreatment of islet allografts prior to transplantation may reduce islet immunogenicity and prolong graft acceptance. We have studied the MHC antigen…”
Get more information

The FCGR2A- Arg131 variant is no major mortality factor in the elderly - evidence from a German centenarian study by Flesch, B. K., Nikolaus, S., El Mokhtari, N. E., Schreiber, S., Nebel, A.

“…Summary The functional single nucleotide polymorphism rs1801274 in the FCGR2A gene (His131Arg) influences the efficiency of hIgG2 binding, the main isotype…”
Get full text

Pretreatment of rat pancreatic islets with MHC I-A monoclonal antibody: in-vitro and in-vivo effects on islet antigenicity by Flesch, B K, Bretzel, R G, Otto, D A, Ernst-Schlegel, M, Federlin, K

“…Pancreatic islet allografts are rejected very rapidly due to their high immunogenicity. Several attempts have been made to reduce the immunogenicity prior to…”
Get more information

ANCA in systemic vasculitides, collagen vascular diseases, rheumatic disorders and inflammatory bowel diseases by Hauschild, S, Schmitt, W H, Csernok, E, Flesch, B K, Rautmann, A, Gross, W L

“…It was the aim of this study to reevaluate the diagnostic significance and clinical implication of ANCA after testing sera from 13,606 patients for the…”
Get more information

The NAnull phenotype of a young man is caused by an FcγRIIIB gene deficiency while the products of the neighboring FcγRIIA and FcγRIIIA genes are present by FLESCH, B. K, ACHTERT, G, BAUER, F, NEPPERT, J

Get full text

'Classic' anti-neutrophil cytoplasmic autoantibodies (cANCA), 'Wegener's autoantigen' and their immunopathogenic role in Wegener's granulomatosis by Gross, W L, Csernok, E, Flesch, B K

“…Wegener's autoantigen (WA), a 29 kD multifunctional protein, is the principal target antigen of autoantibodies associated with Wegener's granulomatosis (WG)…”
Get more information

Impact of culture and cryopreservation on MHC class II antigen expression in canine and porcine islets by Bretzel, R G, Flesch, B K, Hering, B J, Brendel, M, Klitscher, D, Brandhorst, H, Schelz, J, Münch, K P, Federlin, K

“…Canine and porcine islets were either cultured for 10 days at 37 degrees C or cryopreserved. The effect of these treatments on MHC class II antigen expression…”
Get more information

Autoantibodies directed against lysozyme: a new target antigen for anti-neutrophil cytoplasmic antibodies (ANCA) by Schmitt, W H, Csernok, E, Flesch, B K, Hauschild, S, Gross, W L

“…ANCA-positive sera from 1138 patients and ANCA-negative sera from 90 patients were screened for autoantibodies directed against lysozyme (LZ) by ELISA. Sera…”
Get more information

Functions of the Fc receptors for immunoglobulin G by Flesch, Brigitte K., Neppert, Jürgen

Get full text

An experimental analysis of a vibrating guitar string using high-speed photography by Whitfield, S. B, Flesch, K. B

“…We use high-speed photography (1200 frames/s) to investigate the vibrational motion of a plucked guitar string over several cycles. We investigate the…”
Get full text