Search Results - "Flemington, E"

Ribonucleotide reductase represents a novel therapeutic target in primary effusion lymphoma by Dai, L, Lin, Z, Qiao, J, Chen, Y, Flemington, E K, Qin, Z

“…Primary effusion lymphoma (PEL) is a highly aggressive B-cell malignancy that is closely associated with one of oncogenic viruses infection, Kaposi’s…”
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Herpesvirus lytic replication and the cell cycle: arresting new developments by Flemington, E K

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In-depth characterization of a new patient-derived xenograft model for metaplastic breast carcinoma to identify viable biologic targets and patterns of matrix evolution within rare tumor types by Matossian, M. D., Chang, T., Wright, M. K., Burks, H. E., Elliott, S., Sabol, R. A., Wathieu, H., Windsor, G. O., Alzoubi, M. S., King, C. T., Bursavich, J. B., Ham, A. M., Savoie, J. J., Nguyen, K., Baddoo, M., Flemington, E., Sirenko, O., Cromwell, E. F., Hebert, K. L., Lau, F., Izadpanah, R., Brown, H., Sinha, S., Zabaleta, J., Riker, A. I., Moroz, K., Miele, L., Zea, A. H., Ochoa, A., Bunnell, B. A., Collins-Burow, B. M., Martin, E. C., Burow, M. E.

“…Metaplastic breast carcinoma (MBC) is a rare breast cancer subtype with rapid growth, high rates of metastasis, recurrence and drug resistance, and diverse…”
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The Epstein‐Barr virus bZIP transcription factor Zta causes G0/G1 cell cycle arrest through induction of cyclin‐dependent kinase inhibitors by Cayrol, C., Flemington, E. K.

“…While oncoproteins encoded by small DNA tumor viruses and Epstein‐Barr virus (EBV) latent antigens facilitate G1/S progression, the EBV lytic switch…”
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Reactivation of Epstein-Barr virus: regulation and function of the BZLF1 gene by Speck, Samuel H., Chatila, T., Flemington, E.

“…The switch from latent infection to virus replication in Epstein-Barr virus (EBV)-infected B cells is initiated by expression of the viral BZLF1 gene. Recent…”
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E2F-1-Mediated Transactivation is Inhibited by Complex Formation with the Retinoblastoma Susceptibility Gene Product by Flemington, Erik K., Speck, Samuel H., Kaelin, William G.

“…Previous studies have shown that the carboxyl-terminal region of E2F-1 (residues 368-437) can support transcriptional activation when linked to the DNA-binding…”
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Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties by Kaelin, Jr, W G, Krek, W, Sellers, W R, DeCaprio, J A, Ajchenbaum, F, Fuchs, C S, Chittenden, T, Li, Y, Farnham, P J, Blanar, M A

“…An expression vector was modified to permit the rapid synthesis of purified, 32P-labeled, glutathione S-transferase (GST)-retinoblastoma (RB) fusion proteins…”
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Transcription of the E2F-1 gene is rendered cell cycle dependent by E2F DNA-binding sites within its promoter by Neuman, E, Flemington, E K, Sellers, W R, Kaelin, Jr, W G

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Cell Cycle Analysis of Epstein-Barr Virus-Infected Cells following Treatment with Lytic Cycle-Inducing Agents by Rodriguez, A, Jung, E J, Flemington, E K

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Identification of cellular target genes of the Epstein-Barr virus transactivator Zta: activation of transforming growth factor beta igh3 (TGF-beta igh3) and TGF-beta 1 by Cayrol, C, Flemington, E K

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CpG Methylation as a Mechanism for the Regulation of E2F Activity by Campanero, Miguel R., Armstrong, Monica I., Flemington, Erik K.

“…Regulation of gene expression in mammals through methylation of cytosine residues at CpG dinucleotides is involved in the development and progression of…”
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Autoregulation of Epstein-Barr virus putative lytic switch gene BZLF1 by FLEMINGTON, E, SPECK, S. H

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Regulation of E2F through Ubiquitin-Proteasome-Dependent Degradation: Stabilization by the pRB Tumor Suppressor Protein by Campanero, Miguel R., Flemington, Erik K.

“…The E2F family of transcription factors plays a key role in regulating cell-cycle progression. Accordingly, E2F is itself tightly controlled by a series of…”
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Identification of phorbol ester response elements in the promoter of Epstein-Barr virus putative lytic switch gene BZLF1 by FLEMINGTON, E, SPECK, S. H

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Characterization of the Epstein-Barr virus BZLF1 protein transactivation domain by FLEMINGTON, E. K, BORRAS, A. M, LYTLE, J. P, SPECK, S. H

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Transfection-mediated cell synchronization: acceleration of G1-S phase transition by gamma irradiation by Jung, E J, Flemington, E K

“…We have previously provided evidence that the uptake of DNA into cells is cell cycle specific following transfection. We show here that, immediately after…”
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Efficient transcription of the Epstein-Barr virus immediate-early BZLF1 and BRLF1 genes requires protein synthesis by FLEMINGTON, E. K, GOLDFELD, A. E, SPECK, S. H

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Epstein-Barr virus BZLF1 trans activator induces the promoter of a cellular cognate gene, c-fos by FLEMINGTON, E, SPECK, S. H

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Evidence for coiled-coil dimer formation by an Epstein-Barr virus transactivator that lacks a heptad repeat of leucine residues by FLEMINGTON, E, SPECK, S. H

“…Two regions of the Epstein-Barr virus (EBV) BZLF1 gene product, ZEBRA, share sequence homology with c-Fos, one of which corresponds to the DNA binding domain…”
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Transfection-Mediated Cell-Cycle Signaling: Considerations for Transient Transfection-Based Cell-Cycle Studies by Rodriguez, Antonio, Flemington, Erik K.

“…Transient transfection of recombinant genes into cells is a commonly used approach for analyzing cell-cycle- and/or apoptotic-related activities of cell-cycle…”
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