Search Results - "Fleming, Vicki"

CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages by Fergusson, Joannah R., Smith, Kira E., Fleming, Vicki M., Rajoriya, Neil, Newell, Evan W., Simmons, Ruth, Marchi, Emanuele, Björkander, Sophia, Kang, Yu-Hoi, Swadling, Leo, Kurioka, Ayako, Sahgal, Natasha, Lockstone, Helen, Baban, Dilair, Freeman, Gordon J., Sverremark-Ekström, Eva, Davis, Mark M., Davenport, Miles P., Venturi, Vanessa, Ussher, James E., Willberg, Christian B., Klenerman, Paul

“…The C-type lectin CD161 is expressed by a large proportion of human T lymphocytes of all lineages, including a population known as mucosal-associated invariant…”
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Historical zoonoses and other changes in host tropism of Staphylococcus aureus, identified by phylogenetic analysis of a population dataset by Shepheard, Marcus A, Fleming, Vicki M, Connor, Thomas R, Corander, Jukka, Feil, Edward J, Fraser, Christophe, Hanage, William P

“…Staphylococcus aureus exhibits tropisms to many distinct animal hosts. While spillover events can occur wherever there is an interface between host species,…”
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Human MAIT and CD8αα cells develop from a pool of type-17 precommitted CD8+ T cells by Walker, Lucy J., Kang, Yu-Hoi, Smith, Matthew O., Tharmalingham, Hannah, Ramamurthy, Narayan, Fleming, Vicki M., Sahgal, Natasha, Leslie, Alistair, Oo, Ye, Geremia, Alessandra, Scriba, Thomas J., Hanekom, Willem A., Lauer, Georg M., Lantz, Olivier, Adams, David H., Powrie, Fiona, Barnes, Eleanor, Klenerman, Paul

“…Human mucosal associated invariant T (MAIT) CD8+ and Tc17 cells are important tissue-homing cell populations, characterized by high expression of CD161 (++)…”
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How Diverse Is the Genus Wolbachia? Multiple-Gene Sequencing Reveals a Putatively New Wolbachia Supergroup Recovered from Spider Mites (Acari: Tetranychidae) by Ros, Vera I.D, Fleming, Vicki M, Feil, Edward J, Breeuwer, Johannes A.J

“…At least 20% of all arthropods and some nematode species are infected with intracellular bacteria of the genus WOLBACHIA: This highly diverse genus has been…”
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Examining diabetic heel ulcers through an ecological lens: microbial community dynamics associated with healing and infection by Sloan, Tim J, Turton, James C, Tyson, Jess, Musgrove, Alison, Fleming, Vicki M, Lister, Michelle M, Loose, Matthew W, Sockett, R Elizabeth, Diggle, Mathew, Game, Frances L, Jeffcoate, William

“…While some micro-organisms, such as Staphylococcus aureus, are clearly implicated in causing tissue damage in diabetic foot ulcers (DFUs), our knowledge of the…”
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Analysis of CD161 expression on human CD8⁺ T cells defines a distinct functional subset with tissue-homing properties by Billerbeck, Eva, Kang, Yu-Hoi, Walker, Lucy, Lockstone, Helen, Grafmueller, Stefanie, Fleming, Vicki, Flint, Jonathan, Willberg, Chris B, Bengsch, Bertram, Seigel, Bianca, Ramamurthy, Narayan, Zitzmann, Nicole, Barnes, Eleanor J, Thevanayagam, Jonarthan, Bhagwanani, Anisha, Leslie, Alasdair, Oo, Ye H, Kollnberger, Simon, Bowness, Paul, Drognitz, Oliver, Adams, David H, Blum, Hubert E, Thimme, Robert, Klenerman, Paul

“…CD8⁺ T lymphocytes play a key role in host defense, in particular against important persistent viruses, although the critical functional properties of such…”
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CD161-expressing human T cells by Fergusson, Joannah R, Fleming, Vicki M, Klenerman, Paul

“…Expression of the Natural Killer cell receptor CD161 has recently been identified on a subset of T cells, including both CD4+ T helper and CD8+ T cells…”
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Predicting spontaneous clearance of acute hepatitis C virus in a large cohort of HIV-1-infected men by Thomson, Emma C, Fleming, Vicki M, Main, Janice, Klenerman, Paul, Weber, Jonathan, Eliahoo, Joseph, Smith, Jennifer, McClure, Myra O, Karayiannis, Peter

“…An epidemic of acute hepatitis C virus (HCV) infection in HIV-positive men-who-have-sex-with-men (MSM) is emerging in Europe, Australia and the USA. The aim of…”
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Diversity and recombination in Wolbachia and Cardinium from Bryobia spider mites by Ros, Vera I D, Fleming, Vicki M, Feil, Edward J, Breeuwer, Johannes A J

“…Wolbachia and Cardinium are endosymbiotic bacteria infecting many arthropods and manipulating host reproduction. Although these bacteria are maternally…”
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Retrospective screening of routine respiratory samples revealed undetected community transmission and missed intervention opportunities for SARS-CoV-2 in the United Kingdom by Chappell, Joseph G, Tsoleridis, Theocharis, Clark, Gemma, Berry, Louise, Holmes, Nadine, Moore, Christopher, Carlile, Matthew, Sang, Fei, Debebe, Bisrat J, Wright, Victoria, Irving, William L, Thomson, Brian J, Boswell, Timothy C J, Willingham, Iona, Joseph, Amelia, Smith, Wendy, Khakh, Manjinder, Fleming, Vicki M, Lister, Michelle M, Howson-Wells, Hannah C, Holmes, Edward C, Loose, Matthew W, Ball, Jonathan K, McClure, C Patrick, On Behalf Of The Cog-Uk Consortium

“…In the early phases of the SARS coronavirus type 2 (SARS-CoV-2) pandemic, testing focused on individuals fitting a strict case definition involving a limited…”
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Comparative effects of viral-transport-medium heat inactivation upon downstream SARS-CoV-2 detection in patient samples by Thompson, Jamie L, Downie Ruiz Velasco, Angela, Cardall, Alice, Tarbox, Rebecca, Richardson, Jaineeta, Clarke, Gemma, Lister, Michelle, Howson-Wells, Hannah C, Fleming, Vicki M, Khakh, Manjinder, Sloan, Tim, Duckworth, Nichola, Walsh, Sarah, Denning, Chris, McClure, C Patrick, Benest, Andrew V, Seedhouse, Claire H

“…The COVID-19 pandemic, which began in 2020 is testing economic resilience and surge capacity of healthcare providers worldwide. At the time of writing,…”
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Dynamic Coinfection with Multiple Viral Subtypes in Acute Hepatitis C by Smith, Jennifer, Aberle, Judith H., Fleming, Vicki M., Ferenci, Peter, Thomson, Emma C., Karayiannis, Peter, McLean, Angela R., Holzmann, Heidemarie, Klenerman, Paul

“…Introduction. Acute hepatitis C virus (HCV) infection is rarely studied, but virus sequence evolution and hostvirus dynamics during this early stage may…”
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Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution by KASPROWICZ, Victoria, KANG, Yu-Hoi, THIMME, Robert, LEWIS-XIMENEZ, Lia, ALLEN, Todd M, KIM, Arthur Y, KLENERMAN, Paul, LAUER, Georg M, LUCAS, Michaela, ZUR WIESCH, Julian Schulze, KUNTZEN, Thomas, FLEMING, Vicki, NOLAN, Brian E, LONGWORTH, Steven, BERICAL, Andrew, BENGSCH, Bertram

“…Author's Correction ( vol. 85 , p. 4636 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike…”
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Virological footprint of CD4+ T-cell responses during chronic hepatitis C virus infection by Fleming, Vicki M, Harcourt, Gillian, Barnes, Eleanor, Klenerman, Paul

“…Human and animal model evidence suggests that CD4+ T cells play a critical role in the control of chronic hepatitis C virus (HCV) infection. However, despite…”
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What are the prospects for controlling hepatitis C? by Klenerman, Paul, Fleming, Vicki, Barnes, Ellie

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Leukotriene E4 activates human Th2 cells for exaggerated proinflammatory cytokine production in response to prostaglandin D2 by Xue, Luzheng, Barrow, Anna, Fleming, Vicki M, Hunter, Michael G, Ogg, Graham, Klenerman, Paul, Pettipher, Roy

“…PGD(2) exerts a number of proinflammatory responses through a high-affinity interaction with chemoattractant receptor-homologous molecule expressed on Th2…”
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Full-Length Characterization of Hepatitis C Virus Subtype 3a Reveals Novel Hypervariable Regions under Positive Selection during Acute Infection by HUMPHREYS, Isla, FLEMING, Vicki, COLLIER, Jane, GARY HUANG, Kuan-Hsiang, PYBUS, Oliver G, KLENERMAN, Paul, BARNES, Eleanor, FABRIS, Paolo, PARKER, Joe, SCHULENBERG, Bodo, BROWN, Anthony, DEMETRIOU, Charis, GAUDIERI, Silvana, PFAFFEROTT, Katja, LUCAS, Michaela

“…Erratum ( vol. 84 , p. 1664 ) Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious…”
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Agr Interference between Clinical Staphylococcus aureus Strains in an Insect Model of Virulence by FLEMING, Vicki, FEIL, Ed, SEWELL, Andrew K, DAY, Nicholas, BUCKLING, Angus, MASSEY, Ruth C

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Defining the directionality and quality of influenza virus-specific CD8+ T cell cross-reactivity in individuals infected with hepatitis C virus by Kasprowicz, Victoria, Ward, Scott M, Turner, Alison, Grammatikos, Alexandros, Nolan, Brian E, Lewis-Ximenez, Lia, Sharp, Charles, Woodruff, Jenny, Fleming, Vicki M, Sims, Stuart, Walker, Bruce D, Sewell, Andrew K, Lauer, Georg M, Klenerman, Paul

“…Cross-reactivity of murine and recently human CD8(+) T cells between different viral peptides, i.e., heterologous immunity, has been well characterized…”
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Hepatitis C Virus (HCV) Sequence Variation Induces an HCV-Specific T-Cell Phenotype Analogous to Spontaneous Resolution by Kasprowicz, Victoria, Kang, Yu-Hoi, Lucas, Michaela, Schulze zur Wiesch, Julian, Kuntzen, Thomas, Fleming, Vicki, Nolan, Brian E., Longworth, Steven, Berical, Andrew, Bengsch, Bertram, Thimme, Robert, Lewis-Ximenez, Lia, Allen, Todd M., Kim, Arthur Y., Klenerman, Paul, Lauer, Georg M.

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