Search Results - "Fleming, Michael S"

Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain by Cui, Lian, Miao, Xuerong, Liang, Lingli, Abdus-Saboor, Ishmail, Olson, William, Fleming, Michael S., Ma, Minghong, Tao, Yuan-Xiang, Luo, Wenqin

“…The gate control theory (GCT) of pain proposes that pain- and touch-sensing neurons antagonize each other through spinal cord dorsal horn (DH) gating neurons…”
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Identification of Early RET+ Deep Dorsal Spinal Cord Interneurons in Gating Pain by Cui, Lian, Miao, Xuerong, Liang, Lingli, Abdus-Saboor, Ishmail, Olson, William, Fleming, Michael S., Ma, Minghong, Tao, Yuan-Xiang, Luo, Wenqin

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The Majority of Dorsal Spinal Cord Gastrin Releasing Peptide is Synthesized Locally Whereas Neuromedin B is Highly Expressed in Pain- and Itch-Sensing Somatosensory Neurons by Fleming, Michael S, Ramos, Daniel, Han, Seung Baek, Zhao, Jianyuan, Son, Young-Jin, Luo, Wenqin

“…Background: Itch is one of the major somatosensory modalities. Some recent findings have proposed that gastrin releasing peptide (Grp) is expressed in a subset…”
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The anatomy, function, and development of mammalian Aβ low-threshold mechanoreceptors by Fleming, Michael S, Luo, Wenqin

“…t Touch sensation is critical for our social and environmental interactions. In mammals, most discriminative light touch sensation is mediated by the Aβ…”
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A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles by Fleming, Michael S, Li, Jian J, Ramos, Daniel, Li, Tong, Talmage, David A, Abe, Shin-Ichi, Arber, Silvia, Luo, Wenqin

“…Axon-Schwann cell interactions are crucial for the development, function, and repair of the peripheral nervous system, but mechanisms underlying communication…”
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The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size by Janisch, Kerstin M, Vock, Vita M, Fleming, Michael S, Shrestha, Ayushma, Grimsley-Myers, Cynthia M, Rasoul, Bareza A, Neale, Sarah A, Cupp, Timothy D, Kinchen, Jason M, Liem, Jr, Karel F, Dwyer, Noelle D

“…Mammalian neuroepithelial stem cells divide using a polarized form of cytokinesis, which is not well understood. The cytokinetic furrow cleaves the cell by…”
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Preparation of Polymer Coated Gold Nanoparticles by Surface-Confined Living Radical Polymerization at Ambient Temperature by Mandal, Tarun K, Fleming, Michael S, Walt, David R

“…Nanometer sized core−shell particles containing a gold core and poly(methyl methacrylate) (PMMA) shells were prepared by surface-confined living radical…”
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Cis and trans RET signaling control the survival and central projection growth of rapidly adapting mechanoreceptors by Fleming, Michael S, Vysochan, Anna, Paixão, Sόnia, Niu, Jingwen, Klein, Rüdiger, Savitt, Joseph M, Luo, Wenqin

“…RET can be activated in cis or trans by its co-receptors and ligands in vitro, but the physiological roles of trans signaling are unclear. Rapidly adapting…”
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Nanosphere−Microsphere Assembly:  Methods for Core−Shell Materials Preparation by Fleming, Michael S, Mandal, Tarun K, Walt, David R

“…Core−shell composite materials consisting of a silica core and a polystyrene (PS) shell were prepared by colloidal assembly of PS nanospheres onto silica…”
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Production of Hollow Polymeric Microspheres by Surface-Confined Living Radical Polymerization on Silica Templates by Mandal, Tarun K, Fleming, Michael S, Walt, David R

“…Uniform hollow polymer microspheres were prepared by coating silica microsphere templates with poly(benzyl methacrylate) using surface-initiated…”
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A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype by Dwyer, Noelle D, Manning, Danielle K, Moran, Jennifer L, Mudbhary, Raksha, Fleming, Michael S, Favero, Carlita B, Vock, Vita M, O'Leary, Dennis D M, Walsh, Christopher A, Beier, David R

“…The dorsal thalamus acts as a gateway and modulator for information going to and from the cerebral cortex. This activity requires the formation of reciprocal…”
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Stability and Exchange Studies of Alkanethiol Monolayers on Gold-Nanoparticle-Coated Silica Microspheres by Fleming, Michael S, Walt, David R

“…Self-assembled monolayers (SAMs) of carboxylate- and amine-terminated alkanethiols were formed on gold-nanoparticle-coated microspheres. The stability and…”
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Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates by Catcott, Kalli C, McShea, Molly A, Bialucha, Carl Uli, Miller, Kathy L, Hicks, Stuart W, Saxena, Parmita, Gesner, Thomas G, Woldegiorgis, Mikias, Lewis, Megan E, Bai, Chen, Fleming, Michael S, Ettenberg, Seth A, Erickson, Hans K, Yoder, Nicholas C

“…Antibody-drug conjugates (ADCs) are of great interest as targeted cancer therapeutics. Preparation of ADCs for early stage screening is constrained by…”
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High-throughput yeast plasmid overexpression screen by Fleming, Michael S, Gitler, Aaron D

“…The budding yeast, Saccharomyces cerevisiae, is a powerful model system for defining fundamental mechanisms of many important cellular processes, including…”
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A reversed-phase high-performance liquid chromatography method for analysis of monoclonal antibody–maytansinoid immunoconjugates by Fleming, Michael S., Zhang, Wei, Lambert, John M., Amphlett, Godfrey

“…A reversed-phase high-performance liquid chromatography (RP–HPLC) method was developed for detection and quantification of free maytansinoid drug in…”
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High-throughput Yeast Plasmid Overexpression Screen by Fleming, Michael S., Gitler, Aaron D.

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Abstract 5442: Microscale methods for preparation and screening of antibody-drug conjugates by Yoder, Nicholas C., Catcott, Kalli C., McShea, Molly A., Bialucha, Carl Uli, Saxena, Parmita, Bai, Chen, Miller, Kathy L., Gesner, Thomas G., Woldegiorgis, Mikias, Hicks, Stuart W., Lewis, Megan E., Fleming, Michael S., Erickson, Hans K., Ettenberg, Seth E., Keating, Thomas A.

“…Abstract Antibody-drug conjugates (ADCs) are hybrid biotherapeutics that combine the targeting specificity of monoclonal antibodies with chemically conjugated,…”
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Multiple roles of Ret signaling in mechanosensory neuron development by Fleming, Michael S

“…Somatosensation is critical for interaction with the surrounding environment. Somatosensory stimuli are detected by primary somatosensory neurons of the dorsal…”
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Microscale screening of antibody libraries as maytansinoid antibody-drug conjugates by Catcott, Kalli C., McShea, Molly A., Bialucha, Carl Uli, Miller, Kathy L., Hicks, Stuart W., Saxena, Parmita, Gesner, Thomas G., Woldegiorgis, Mikias, Lewis, Megan E., Bai, Chen, Fleming, Michael S., Ettenberg, Seth A., Erickson, Hans K., Yoder, Nicholas C.

“…Antibody-drug conjugates (ADCs) are of great interest as targeted cancer therapeutics. Preparation of ADCs for early stage screening is constrained by…”
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Automated inventory and material science scoping calculations under fission and fusion conditions by Gilbert, Mark R, Fleming, Michael, Sublet, Jean-Christophe

“…The FISPACT-II inventory simulation platform is a modern computational tool with advanced and unique capabilities. It is sufficiently flexible and efficient to…”
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