Search Results - "Fleming, Jodie M."

Race-associated biological differences among luminal A and basal-like breast cancers in the Carolina Breast Cancer Study by Parada, Jr, Humberto, Sun, Xuezheng, Fleming, Jodie M, Williams-DeVane, ClarLynda R, Kirk, Erin L, Olsson, Linnea T, Perou, Charles M, Olshan, Andrew F, Troester, Melissa A

“…We examined racial differences in the expression of eight genes and their associations with risk of recurrence among 478 white and 495 black women who…”
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Mammary extracellular matrix directs differentiation of testicular and embryonic stem cells to form functional mammary glands in vivo by Bruno, Robert D., Fleming, Jodie M., George, Andrea L., Boulanger, Corinne A., Schedin, Pepper, Smith, Gilbert H.

“…Previously, we demonstrated the ability of the normal mammary microenvironment (niche) to direct non-mammary cells including testicular and embryonic stem…”
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A functional role for the cancer disparity-linked genes, CRYβB2 and CRYβB2P1, in the promotion of breast cancer by Barrow, Maya A, Martin, Megan E, Coffey, Alisha, Andrews, Portia L, Jones, Gieira S, Reaves, Denise K, Parker, Joel S, Troester, Melissa A, Fleming, Jodie M

“…In the USA, the breast cancer mortality rate is 41% higher for African-American women than non-Hispanic White women. While numerous gene expression studies…”
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The role of lipolysis stimulated lipoprotein receptor in breast cancer and directing breast cancer cell behavior by Reaves, Denise K, Fagan-Solis, Katerina D, Dunphy, Karen, Oliver, Shannon D, Scott, David W, Fleming, Jodie M

“…The claudin-low molecular subtype of breast cancer is of particular interest for clinically the majority of these tumors are poor prognosis, triple negative,…”
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Hepatocyte growth factor pathway expression in breast cancer by race and subtype by Jones, Gieira S, Hoadley, Katherine A, Olsson, Linnea T, Hamilton, Alina M, Bhattacharya, Arjun, Kirk, Erin L, Tipaldos, Heather J, Fleming, Jodie M, Love, Michael I, Nichols, Hazel B, Olshan, Andrew F, Troester, Melissa A

“…African American women have the highest risk of breast cancer mortality compared to other racial groups. Differences in tumor characteristics have been…”
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Clostridium and bacillus binary enterotoxins: bad for the bowels, and eukaryotic being by Stiles, Bradley G, Pradhan, Kisha, Fleming, Jodie M, Samy, Ramar Perumal, Barth, Holger, Popoff, Michel R

“…Some pathogenic spore-forming bacilli employ a binary protein mechanism for intoxicating the intestinal tracts of insects, animals, and humans. These…”
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Nuclear Localized LSR: A Novel Regulator of Breast Cancer Behavior and Tumorigenesis by Reaves, Denise K, Hoadley, Katherine A, Fagan-Solis, Katerina D, Jima, Dereje D, Bereman, Michael, Thorpe, Lynnelle, Hicks, Jyla, McDonald, David, Troester, Melissa A, Perou, Charles M, Fleming, Jodie M

“…Lipolysis-stimulated lipoprotein receptor (LSR) has been found in the plasma membrane and is believed to function in lipoprotein endocytosis and tight…”
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Local regulation of human breast xenograft models by Fleming, Jodie M., Miller, Tyler C., Meyer, Matthew J., Ginsburg, Erika, Vonderhaar, Barbara K.

“…Breast cancer studies implant human cancer cells under the renal capsule, subcutaneously, or orthotopically and often use estrogen supplementation and immune…”
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Hornerin, an S100 family protein, is functional in breast cells and aberrantly expressed in breast cancer by Fleming, Jodie M, Ginsburg, Erika, Oliver, Shannon D, Goldsmith, Paul, Vonderhaar, Barbara K

“…Recent evidence suggests an emerging role for S100 protein in breast cancer and tumor progression. These ubiquitous proteins are involved in numerous normal…”
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Role of HGF in epithelial-stromal cell interactions during progression from benign breast disease to ductal carcinoma in situ by Casbas-Hernandez, Patricia, D'Arcy, Monica, Roman-Perez, Erick, Brauer, Heather Ann, McNaughton, Kirk, Miller, Samantha M, Chhetri, Raghav K, Oldenburg, Amy L, Fleming, Jodie M, Amos, Keith D, Makowski, Liza, Troester, Melissa A

“…Basal-like and luminal breast cancers have distinct stromal-epithelial interactions, which play a role in progression to invasive cancer. However, little is…”
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Gene Expression Analysis of In Vitro Cocultures to Study Interactions between Breast Epithelium and Stroma by Casbas-Hernandez, Patricia, Fleming, Jodie M., Troester, Melissa A.

“…The interactions between breast epithelium and stroma are fundamental to normal tissue homeostasis and for tumor initiation and progression. Gene expression…”
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Experimental data demonstrating the effects of silver nanoparticles on basement membrane gene and protein expression in cultured colon, mammary and bronchial epithelia by Yeyeodu, Susan T., Martin, Megan E., Reaves, Denise K., Enders, Jeffrey R., Costantini, Lindsey M., Fleming, Jodie M.

“…This data article is related to the research article entitled “Silver nanoparticles alter epithelial basement membrane integrity, cell adhesion molecule…”
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The normal breast microenvironment of premenopausal women differentially influences the behavior of breast cancer cells in vitro and in vivo by Fleming, Jodie M, Miller, Tyler C, Quinones, Mariam, Xiao, Zhen, Xu, Xia, Meyer, Matthew J, Ginsburg, Erika, Veenstra, Timothy D, Vonderhaar, Barbara K

“…Breast cancer studies frequently focus on the role of the tumor microenvironment in the promotion of cancer; however, the influence of the normal breast…”
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Challenging the roles of CD44 and lipolysis stimulated lipoprotein receptor in conveying Clostridium perfringens iota toxin cytotoxicity in breast cancer by Fagan-Solis, Katerina D, Reaves, Denise K, Rangel, M Cristina, Popoff, Michel R, Stiles, Bradley G, Fleming, Jodie M

“…Translational exploration of bacterial toxins has come to the forefront of research given their potential as a chemotherapeutic tool. Studies in select tissues…”
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Progesterone receptor activates Msx2 expression by downregulating TNAP/Akp2 and activating the Bmp pathway in EpH4 mouse mammary epithelial cells by Fleming, Jodie M, Ginsburg, Erika, Goldhar, Anita S, Plant, Joshua, Vonderhaar, Barbara K

“…Previously we demonstrated that EpH4 mouse mammary epithelial cells induced the homeobox transcription factor Msx2 either when transfected with the…”
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The mitogen-activated protein kinase pathway tonically inhibits both basal and IGF-I-stimulated IGF-binding protein-5 production in mammary epithelial cells by Fleming, Jodie M, Brandimarto, Jeffrey A, Cohick, Wendie S

“…The IGF system plays a key role in mammary gland growth and development. Our lab previously reported that IGF-I primarily regulates IGF-binding protein (BP)-3…”
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Persistent organic pollutants and obesity: are they potential mechanisms for breast cancer promotion? by Reaves, Denise K, Ginsburg, Erika, Bang, John J, Fleming, Jodie M

“…Dietary ingestion of persistent organic pollutants (POPs) is correlated with the development of obesity. Obesity alters metabolism, induces an inflammatory…”
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Obesity and Breast Cancer Metastasis across Genomic Subtypes by Olsson, Linnea T, Walens, Andrea, Hamilton, Alina M, Benefield, Halei C, Fleming, Jodie M, Carey, Lisa A, Hursting, Stephen D, Williams, Kevin P, Troester, Melissa A

“…Obese women have higher risk of aggressive breast tumors and distant metastasis. However, obesity has rarely been assessed in association with metastasis in…”
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CD44posCD49fhiCD133/2hi Defines Xenograft-Initiating Cells in Estrogen Receptor-Negative Breast Cancer by MEYER, Matthew J, FLEMING, Jodie M, LIN, Amy F, AMAL HUSSNAIN, S, GINSBURG, Erika, VONDERHAAR, Barbara K

“…Defining the populations of tumor-initating cells that are present in tumors is a first step in developing therapeutics to target these cells. We show here…”
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In Situ Drug Delivery to Breast Cancer-Associated Extracellular Matrix by Fleming, Jodie M, Yeyeodu, Susan T, McLaughlin, Ashley, Schuman, Darren, Taylor, Darlene K

“…The extracellular matrix (ECM) contributes to tumor progression through changes induced by tumor and stromal cell signals that promote increased ECM density…”
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