Search Results - "Fleming, James F."
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nRCFV: a new, dataset-size-independent metric to quantify compositional heterogeneity in nucleotide and amino acid datasets
Published in BMC bioinformatics (12-04-2023)“…Compositional heterogeneity-when the proportions of nucleotides and amino acids are not broadly similar across the dataset-is a cause of a great number of…”
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The Evolution of Temperature and Desiccation-Related Protein Families in Tardigrada Reveals a Complex Acquisition of Extremotolerance
Published in Genome biology and evolution (05-01-2024)“…Tardigrada is an ecdysozoan lineage famed for its resilience. Tardigrades can tolerate high doses of radiation, low-oxygen environments, desiccation, and both…”
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Identifying and addressing methodological incongruence in phylogenomics: A review
Published in Evolutionary applications (01-06-2023)“…The availability of phylogenetic data has greatly expanded in recent years. As a result, a new era in phylogenetic analysis is dawning—one in which the methods…”
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A Novel Approach to Investigate the Effect of Tree Reconstruction Artifacts in Single-Gene Analysis Clarifies Opsin Evolution in Nonbilaterian Metazoans
Published in Genome biology and evolution (01-02-2020)“…Abstract Our ability to correctly reconstruct a phylogenetic tree is strongly affected by both systematic errors and the amount of phylogenetic signal in the…”
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Eye-Transcriptome and Genome-Wide Sequencing for Scolecophidia: Implications for Inferring the Visual System of the Ancestral Snake
Published in Genome biology and evolution (01-12-2021)“…Abstract Molecular genetic data have recently been incorporated in attempts to reconstruct the ecology of the ancestral snake, though this has been limited by…”
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The wealth of shared resources: Improving molecular taxonomy using eDNA and public databases
Published in Zoologica scripta (01-05-2023)“…Public databases such as the NCBI's GenBank have been used as repositories for genomic studies for more than 30 years. In this time, our understanding of the…”
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Systematics of tardigrada: A reanalysis of tardigrade taxonomy with specific reference to Guil et al. (2019)
Published in Zoologica scripta (01-05-2021)“…The Tardigrada are a clade with a disputed and complex taxonomy. The three traditional tardigrade classes are the Heterotardigrada, Eutardigrada and the…”
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Comprehensive Transcriptome Sequencing of Tanaidacea with Proteomic Evidences for Their Silk
Published in Genome biology and evolution (01-12-2021)“…Abstract Tanaidaceans are small benthic crustaceans that mainly inhabit diverse marine environments, and they comprise one of the most diverse and abundant…”
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Uncertain-tree: discriminating among competing approaches to the phylogenetic analysis of phenotype data
Published in Proceedings of the Royal Society. B, Biological sciences (11-01-2017)“…Morphological data provide the only means of classifying the majority of life's history, but the choice between competing phylogenetic methods for the analysis…”
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Pancrustacean Evolution Illuminated by Taxon-Rich Genomic-Scale Data Sets with an Expanded Remipede Sampling
Published in Genome biology and evolution (01-08-2019)“…Abstract The relationships of crustaceans and hexapods (Pancrustacea) have been much discussed and partially elucidated following the emergence of phylogenomic…”
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New Tardigrade Opsins and Differential Expression Analyses Show Ontogenic Variation in Light Perception
Published in Genome biology and evolution (03-08-2021)“…Abstract Opsins are light-sensitive proteins involved in many photoreceptive processes, including, but not limited to, vision and regulation of circadian…”
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The Ediacaran origin of Ecdysozoa; integrating fossil and phylogenomic data
Published in Journal of the Geological Society (01-07-2022)“…Ecdysozoans (Phyla Arthropoda, Kinorhyncha, Loricifera, Nematoda, Nematomorpha, Onychophora, Priapulida, Tardigrada) are invertebrates bearing a tough,…”
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Molecular palaeontology illuminates the evolution of ecdysozoan vision
Published in Proceedings of the Royal Society. B, Biological sciences (05-12-2018)“…Colour vision is known to have arisen only twice—once in Vertebrata and once within the Ecdysozoa, in Arthropoda. However, the evolutionary history of…”
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Translocation-arrested Apolipoprotein B Evades Proteasome Degradation via a Sterol-sensitive Block in Ubiquitin Conjugation
Published in The Journal of biological chemistry (15-01-1999)“…In this study, we explored how sterol metabolism altered by the expression of cholesterol-7α-hydroxylase NADPH:oxygen oxidoreductase (7α-hydroxylase) affects…”
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Hagfish genome elucidates vertebrate whole-genome duplication events and their evolutionary consequences
Published in Nature ecology & evolution (01-03-2024)“…Polyploidy or whole-genome duplication (WGD) is a major event that drastically reshapes genome architecture and is often assumed to be causally associated with…”
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Uncertain-tree: discriminating among competing approaches to the phylogenetic analysis of phenotype data
Published in Proceedings of the Royal Society. B, Biological sciences (11-01-2017)“…Morphological data provide the only means of classifying the majority of life's history, but the choice between competing phylogenetic methods for the analysis…”
Get full text
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Chinese Hamster Ovary Cells Require the Coexpression of Microsomal Triglyceride Transfer Protein and Cholesterol 7α-Hydroxylase for the Assembly and Secretion of Apolipoprotein B-containing Lipoproteins
Published in The Journal of biological chemistry (02-04-1999)“…Due to the absence of microsomal triglyceride transfer protein (MTP), Chinese hamster ovary (CHO) cells lack the ability to translocate apoB into the lumen of…”
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Chinese Hamster Ovary Cells Require the Coexpression of Microsomal Triglyceride Transfer Protein and Cholesterol 7α-Hydroxylase for the Assembly and Secretion of Apolipoprotein B-containing Lipoproteins
Published in The Journal of biological chemistry (02-04-1999)“…Due to the absence of microsomal triglyceride transfer protein (MTP), Chinese hamster ovary (CHO) cells lack the ability to translocate apoB into the lumen of…”
Get full text
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