Search Results - "Fleming, Elizabeth S."

Nanog, Pou5f1 and SoxB1 activate zygotic gene expression during the maternal-to-zygotic transition by Lee, Miler T., Bonneau, Ashley R., Takacs, Carter M., Bazzini, Ariel A., DiVito, Kate R., Fleming, Elizabeth S., Giraldez, Antonio J.

“…After fertilization, maternal factors direct development and trigger zygotic genome activation (ZGA) at the maternal-to-zygotic transition (MZT). In zebrafish,…”
Get full text

Planar Spindle Orientation and Asymmetric Cytokinesis in the Mouse Small Intestine by Fleming, Elizabeth S, Zajac, Mark, Moschenross, Darcy M, Montrose, David C, Rosenberg, Daniel W, Cowan, Ann E, Tirnauer, Jennifer S

“…A major feature of epithelial cell polarity is regulated positioning of the mitotic spindle within the cell. Spindles in cells of symmetrically expanding…”
Get full text

Identification of small ORFs in vertebrates using ribosome footprinting and evolutionary conservation by Bazzini, Ariel A, Johnstone, Timothy G, Christiano, Romain, Mackowiak, Sebastian D, Obermayer, Benedikt, Fleming, Elizabeth S, Vejnar, Charles E, Lee, Miler T, Rajewsky, Nikolaus, Walther, Tobias C, Giraldez, Antonio J

“…Identification of the coding elements in the genome is a fundamental step to understanding the building blocks of living systems. Short peptides (< 100 aa)…”
Get full text

Skin Microbiome Variation with Cancer Progression in Human Cutaneous Squamous Cell Carcinoma by Voigt, Anita Y., Emiola, Akintunde, Johnson, Jethro S., Fleming, Elizabeth S., Nguyen, Hoan, Zhou, Wei, Tsai, Kenneth Y., Fink, Christine, Oh, Julia

“…The skin microbiome plays a critical role in skin homeostasis and disorders. UVR is the major cause of nonmelanoma skin cancer, but other risk factors,…”
Get full text

Spindle misorientation in tumors from APC(min/+) mice by Fleming, Elizabeth S, Temchin, Maura, Wu, Qian, Maggio-Price, Lillian, Tirnauer, Jennifer S

“…The adenomatous polyposis coli (APC) tumor suppressor gene is mutated in the majority of colon cancers, and its mutation may initiate cancer by multiple…”
Get full text

Resilience-Based Performance Measures for Next-Generation Systems Security Engineering by Williams, Adam D., Adams, Thomas, Wingo, Jamie, Birch, Gabriel C., Caskey, Susan A., Fleming, Elizabeth S., Gunda, Thushara

“…Performance measures commonly used in systems security engineering tend to be static, linear, and have limited utility in addressing challenges to security…”
Get full text

Spindle misorientation in tumors from APCmin/+ mice by Fleming, Elizabeth S., Temchin, Maura, Wu, Qian, Maggio-Price, Lillian, Tirnauer, Jennifer S.

“…The adenomatous polyposis coli (APC) tumor suppressor gene is mutated in the majority of colon cancers, and its mutation may initiate cancer by multiple…”
Get full text

Incorporating the Role(s) of Human Actors in Complex System Design for Safety and Security by Fleming, Elizabeth S., Williams, Adam D.

“…ABSTRACT Traditional systems engineering demonstrates the importance of customer needs in scoping and defining design requirements; yet, in practice, other…”
Get full text

Pilot compliance to TCAS Resolution Advisories by Pritchett, Amy, Fleming, Elizabeth S.

“…This paper summarizes insights into pilot compliance to Traffic alert and Collision Avoidance System (TCAS) Resolution Advisories (RA's), as gained in a series…”
Get full text

Restoration of Both Structure and Function to a Defective Poly(A) Site by in Vitro Selection by Graveley, Brenton R., Fleming, Elizabeth S., Gilmartin, Gregory M.

“…Efficient cleavage and polyadenylation at the human immunodeficiency virus type-1 (HIV-1) poly(A) site requires an upstream 3ʹ-processing enhancer to overcome…”
Get full text

Multilayer Network Models for Coordinating Orchestration of Systems Security Engineering by Williams, Adam D., Birch, Gabriel C., Caskey, Susan A., Fleming, Elizabeth S.

“…Systems security engineering (SSE) faces new internal (e.g., increased digitization) and external (e.g., adversary capabilities) obstacles as systems increase…”
Get full text

Insights for Systems Security Engineering from Multilayer Network Models by Williams, Adam D., Birch, Gabriel C., Caskey, Susan A., Fleming, Elizabeth S., Gunda, Thushara, Adams, Thomas, Wingo, Jamie

“…Next‐generation approaches for systems security engineering will need to address challenges stemming from complex risk environments, innovative adversaries,…”
Get full text

Examining an Improved Pilot Training Program for TCAS by Fleming, Elizabeth S., Pritchett, Amy R.

“…This paper discusses the development and evaluation of a training program intended to train pilots to understand Traffic alert and Collision Avoidance System…”
Get full text

Spindle misorientation in tumors from APC min/+ mice by Fleming, Elizabeth S., Temchin, Maura, Wu, Qian, Maggio‐Price, Lillian, Tirnauer, Jennifer S.

“…The adenomatous polyposis coli ( APC ) tumor suppressor gene is mutated in the majority of colon cancers, and its mutation may initiate cancer by multiple…”
Get full text

Pilot’s Information Use During TCAS Events, and Relationship to Compliance to TCAS Resolution Advisories by Pritchett, Amy R., Fleming, Elizabeth S., Cleveland, William P., Popescu, Vlad M., Thakkar, Dhruv A., Zoetrum, Jonathan J.

“…The Traffic alert and Collision Avoidance System (TCAS) is intended to serve as a backup, redundant system that alerts and advises the pilot when all other…”
Get full text

CPSF recognition of an HIV-1 mRNA 3'-processing enhancer: multiple sequence contacts involved in poly(A) site definition by Gilmartin, G M, Fleming, E S, Oetjen, J, Graveley, B R

“…The endonucleolytic cleavage and polyadenylation of a pre-mRNA in mammalian cells requires two cis-acting elements, a highly conserved AAUAAA hexamer and an…”
Get full text

Activation of HIV‐1 pre‐mRNA 3′ processing in vitro requires both an upstream element and TAR by Gilmartin, G.M., Fleming, E.S., Oetjen, J.

“…The architecture of the human immunodeficiency virus type 1 (HIV‐1) genome presents an intriguing dilemma for the 3′ processing of viral transcripts‐‐to…”
Get full text

RNA structure is a critical determinant of poly(A) site recognition by cleavage and polyadenylation specificity factor by Graveley, Brenton R., Fleming, Elizabeth S., Gilmartin, Gregory M.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Monocytes From Peanut-Allergic Patients Express Higher Levels Of RALDH2 In Response To Peanut Protein Than Monocytes From Tolerant Subjects by Fleming, Elizabeth, BS, Ruiter, Bert, PhD, Hurlburt, Barry K., PhD, Maleki, Soheila J., PhD, Shreffler, Wayne G., MD, PhD, FAAAAI

Get full text

Peanut Protein Induces Expression Of RALDH2 In Human Dendritic Cells In a TLR2-Dependent Manner by Ruiter, Bert, PhD, Fleming, Elizabeth, BS, Hurlburt, Barry K., PhD, Maleki, Soheila J., PhD, Shreffler, Wayne G., MD, PhD, FAAAAI

Get full text