Search Results - "Fleitas Kanonnikoff, Tania"
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A phase Ib/II study of HER3-targeting lumretuzumab in combination with carboplatin and paclitaxel as first-line treatment in patients with advanced or metastatic squamous non-small cell lung cancer
Published in ESMO open (01-07-2019)“…PurposeThis study investigated the safety and clinical activity of lumretuzumab, a humanised antihuman epidermal growth factor receptor 3 (HER3) monoclonal…”
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First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors
Published in Clinical cancer research (15-02-2016)“…A first-in-human phase I study was conducted to characterize safety, efficacy, and pharmacokinetic (PK) and pharmacodynamic (PD) properties of lumretuzumab, a…”
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Assessing molecular subtypes of gastric cancer: microsatellite unstable and Epstein-Barr virus subtypes. Methods for detection and clinical and pathological implications
Published in ESMO open (2019)“…BackgroundThe molecular classification of gastric cancer recognises two subtypes prone to immune checkpoint blockade: the microsatellite unstable and the…”
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Foundational Models for Pathology and Endoscopy Images: Application for Gastric Inflammation
Published in Diagnostics (Basel) (30-08-2024)“…The integration of artificial intelligence (AI) in medical diagnostics represents a significant advancement in managing upper gastrointestinal (GI) cancer,…”
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Molecular profile in Paraguayan colorectal cancer patients, towards to a precision medicine strategy
Published in Cancer medicine (Malden, MA) (01-06-2019)“…Somatic mutation analysis and evaluation of microsatellite instability (MSI) have become mandatory for selecting personalized therapy strategies for advanced…”
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Immune checkpoint inhibitors for first-line treatment of advanced esophageal squamous cell carcinoma
Published in Med (New York, N.Y. : Online) (13-09-2024)“…Immunotherapy has revolutionized the treatment landscape of esophageal squamous cell carcinoma. He et al. present the final results of the randomized phase 3…”
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SEOM-GEMCAD-TTD clinical guideline for the diagnosis and treatment of gastric cancer (2023)
Published in Clinical & translational oncology (01-11-2024)“…Gastric cancer (GC) is the fifth most common cancer worldwide with a varied geographic distribution and an aggressive behavior. In Spain, the incidence is…”
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Incidence and Survival Outcomes of Gastrointestinal Stromal Tumors
Published in JAMA network open (01-08-2024)“…The incidence of gastrointestinal stromal tumors (GISTs) increased after the implementation of GIST-specific histology coding in 2001, but updated data on…”
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Abstract CT122: A phase 2, multi-center, open-label study of cinrebafusp alfa (PRS-343) in combination with ramucirumab and paclitaxel in patients with HER2-positive gastric or gastroesophageal junction (GEJ) adenocarcinoma and in combination with tucatinib in patients with HER2 low gastric or gastroesophageal junction (GEJ) adenocarcinoma
Published in Cancer research (Chicago, Ill.) (15-06-2022)“…Abstract Background: For patients (pts) with HER2-overexpressing metastatic gastric cancer, trastuzumab + chemotherapy +/- pembrolizumab is a standard…”
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Neoadjuvant treatment for locally advanced unresectable and borderline resectable pancreatic cancer: oncological outcomes at a single academic centre
Published in ESMO open (23-11-2020)“…IntroductionPancreatic cancer (PC), even in the absence of metastatic disease, has a dismal prognosis. One-third of them are borderline resectable (BRPC) or…”
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Foundational Models for Pathology and Endoscopy Images: Application for Gastric Inflammation
Published 26-06-2024“…The integration of artificial intelligence (AI) in medical diagnostics represents a significant advancement in managing upper gastrointestinal (GI) cancer, a…”
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