Search Results - "Fleiss, B."

Melatonin augments hypothermic neuroprotection in a perinatal asphyxia model by ROBERTSON, Nicola J, FAULKNER, Stuart, HRISTOVA, Mariya, CADY, Ernest B, GRESSENS, Pierre, GOLAY, Xavier, RAIVICH, Gennadij, FLEISS, Bobbi, BAINBRIDGE, Alan, ANDORKA, Csilla, PRICE, David, POWELL, Elizabeth, LECKY-THOMPSON, Lucy, THEI, Laura, CHANDRASEKARAN, Manigandan

“…Despite treatment with therapeutic hypothermia, almost 50% of infants with neonatal encephalopathy still have adverse outcomes. Additional treatments are…”
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Innovative laboratory unit for pre-testing of oxygen carriers for chemical-looping combustion by Fleiß, B., Fuchs, J., Penthor, S., Arlt, S., Pachler, R., Müller, S., Hofbauer, H.

“…Chemical-looping combustion (CLC) is a highly efficient CO 2 separation technology with no direct contact between combustion air and fuel. A metal oxide is…”
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Pharmacokinetics of dexmedetomidine combined with therapeutic hypothermia in a piglet asphyxia model by EZZATI, M., BROAD, K., KAWANO, G., FAULKNER, S., HASSELL, J., FLEISS, B., GRESSENS, P., FIERENS, I., ROSTAMI, J., MAZE, M., SLEIGH, J. W., ANDERSON, B., SANDERS, R. D., ROBERTSON, N. J.

“…Background The highly selective α2‐adrenoreceptor agonist, dexmedetomidine, exerts neuroprotective, analgesic, anti‐inflammatory and sympatholytic properties…”
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Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro by Dean, J.M, Wang, X, Kaindl, A.M, Gressens, P, Fleiss, B, Hagberg, H, Mallard, C

“…Abstract Although the role of microglial activation in neural injury remains controversial, there is increasing evidence for a detrimental effect in the…”
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Effects of birth asphyxia on neonatal hippocampal structure and function in the spiny mouse by Fleiss, B., Coleman, H.A., Castillo-Melendez, M., Ireland, Z., Walker, D.W., Parkington, H.C.

“…► Hippocampal plasticity and cytoarchitecture were assessed after birth asphyxia in the spiny mouse. ► Asphyxia reduced plasticity but caused no infarct or…”
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Long-term cerebral effects of perinatal inflammation by Chhor, V, Schang, A-L, Favrais, G, Fleiss, B, Gressens, P

“…Perinatal inflammation can lead to fetal/neonatal inflammatory syndrome, a risk factor for brain lesions, especially in the white matter. Perinatal…”
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Corrigendum to “Microglial MyD88 signaling regulates acute neuronal toxicity of LPS-stimulated microglia in vitro” [Brain Behav. Immun. 24 (2010) 776–783] by Dean, J.M, Wang, X, Kaindl, A.M, Gressens, P, Fleiss, B, Hagberg, H, Mallard, C

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Tertiary mechanisms of brain damage: a new hope for treatment of cerebral palsy? by Fleiss, Bobbi, Dr, Gressens, Pierre, Prof

“…Summary Cerebral palsy is caused by injury or developmental disturbances to the immature brain and leads to substantial motor, cognitive, and learning…”
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Lipopolysaccharide‐induced alteration of mitochondrial morphology induces a metabolic shift in microglia modulating the inflammatory response in vitro and in vivo by Nair, Syam, Sobotka, Kristina S., Joshi, Pooja, Gressens, Pierre, Fleiss, Bobbi, Thornton, Claire, Mallard, Carina, Hagberg, Henrik

“…Accumulating evidence suggests that changes in the metabolic signature of microglia underlie their response to inflammation. We sought to increase our…”
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Characterization of phenotype markers and neuronotoxic potential of polarised primary microglia in vitro by Chhor, Vibol, Le Charpentier, Tifenn, Lebon, Sophie, Oré, Marie-Virgine, Celador, Idoia Lara, Josserand, Julien, Degos, Vincent, Jacotot, Etienne, Hagberg, Henrik, Sävman, Karin, Mallard, Carina, Gressens, Pierre, Fleiss, Bobbi

“…Highlight ► A unique catalogue of phenotype markers and neuronotoxic effects of polarised primary microglia, as a comparative tool to screen neurotherapies…”
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Conséquences cérébrales à long terme de l’inflammation périnatale by Chhor, V., Schang, A.-L., Favrais, G., Fleiss, B., Gressens, P.

“…L’inflammation périnatale est responsable d’un syndrome inflammatoire fœtal ou néonatal dont le rôle est démontré, aussi bien chez l’animal que chez l’Homme,…”
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Severe intraventricular hemorrhage causes long-lasting structural damage in a preterm rabbit pup model by Romantsik, Olga, Ross-Munro, Emily, Grönlund, Susanne, Holmqvist, Bo, Brinte, Anders, Gerdtsson, Erik, Vallius, Suvi, Bruschettini, Matteo, Wang, Xiaoyang, Fleiss, Bobbi, Ley, David

“…Background Intraventricular hemorrhage causes significant lifelong mortality and morbidity, especially in preterm born infants. Progress in finding an…”
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Acute LPS sensitization and continuous infusion exacerbates hypoxic brain injury in a piglet model of neonatal encephalopathy by Martinello, Kathryn A., Meehan, Christopher, Avdic-Belltheus, Adnan, Lingam, Ingran, Ragab, Sara, Hristova, Mariya, Tann, Cally J., Peebles, Donald, Hagberg, Henrik, Wolfs, Tim G. A. M., Klein, Nigel, Tachtsidis, Ilias, Golay, Xavier, Kramer, Boris W., Fleiss, Bobbi, Gressens, Pierre, Robertson, Nicola J.

“…Co-existing infection/inflammation and birth asphyxia potentiate the risk of developing neonatal encephalopathy (NE) and adverse outcome. In a newborn piglet…”
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Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia–ischemia by Martinello, Kathryn A., Meehan, Christopher, Avdic-Belltheus, Adnan, Lingam, Ingran, Mutshiya, Tatenda, Yang, Qin, Akin, Mustafa Ali, Price, David, Sokolska, Magdalena, Bainbridge, Alan, Hristova, Mariya, Tachtsidis, Ilias, Tann, Cally J., Peebles, Donald, Hagberg, Henrik, Wolfs, Tim G. A. M., Klein, Nigel, Kramer, Boris W., Fleiss, Bobbi, Gressens, Pierre, Golay, Xavier, Robertson, Nicola J.

“…Background Perinatal inflammation combined with hypoxia–ischemia (HI) exacerbates injury in the developing brain. Therapeutic hypothermia (HT) is standard care…”
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Systemic stimulation of TLR2 impairs neonatal mouse brain development by Du, Xiaonan, Fleiss, Bobbi, Li, Hongfu, D'angelo, Barbara, Sun, Yanyan, Zhu, Changlian, Hagberg, Henrik, Levy, Ofer, Mallard, Carina, Wang, Xiaoyang

“…Inflammation is associated with perinatal brain injury but the underlying mechanisms are not completely characterized. Stimulation of Toll-like receptors…”
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Neuroprotection by the histone deacetylase inhibitor trichostatin A in a model of lipopolysaccharide-sensitised neonatal hypoxic-ischaemic brain injury by Fleiss, Bobbi, Nilsson, Marie K L, Blomgren, Klas, Mallard, Carina

“…Perinatal brain injury is complex and often associated with both inflammation and hypoxia-ischaemia (HI). In adult inflammatory brain injury models, therapies…”
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A Critical Review of Models of Perinatal Infection by Dean, Justin M, Shi, Zhongjie, Fleiss, Bobbi, Gunn, Katherine C, Groenendaal, Floris, van Bel, Frank, Derrick, Matthew, Juul, Sandra E, Tan, Sidhartha, Gressens, Pierre, Mallard, Carina, Bennet, Laura, Gunn, Alistair J

“…One of the central, unanswered questions in perinatology is why preterm infants continue to have such poor long-term neurodevelopmental, cognitive and learning…”
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PS-339Therapeutic Hypothermia In The Asphyctic Newborn: Immunohistochemical Comparison Of Three Cooling Target Temperatures In The Piglet Brain by Alonso Alconada, D, Broad, K, Bainbridge, A, Chandrasekaran, M, Faulkner, S D, Kerenyi, A, Hassell, K J, Fleiss, B, Bennett, K, Kelen, D, Cady, E, Gressens, P, Golay, X, Robertson, N J

“…Background and aimsTherapeutic hypothermia has now become standard of care for neonatal hypoxic-ischaemic brain injury, as it reduces death and neurological…”
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Therapeutic hypothermia in the asphyctic newborn: immunohistochemical comparison of three cooling target temperatures in the piglet brain by Alconada, D Alonso, Broad, K, Bainbridge, A, Chandrasekaran, M, Faulkner, SD, Kerenyi, A, Hassell, KJ, Fleiss, B, Bennett, K, Kelen, D, Cady, E, Gressens, P, Golay, X, Robertson, NJ

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PS-339 Therapeutic Hypothermia In The Asphyctic Newborn: Immunohistochemical Comparison Of Three Cooling Target Temperatures In The Piglet Brain by Alonso Alconada, D, Broad, K, Bainbridge, A, Chandrasekaran, M, Faulkner, SD, Kerenyi, A, Hassell, KJ, Fleiss, B, Bennett, K, Kelen, D, Cady, E, Gressens, P, Golay, X, Robertson, NJ

“…Background and aimsTherapeutic hypothermia has now become standard of care for neonatal hypoxic-ischaemic brain injury, as it reduces death and neurological…”
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