Search Results - "Fleenor, Donald E."
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Self-inflicted DNA double-strand breaks sustain tumorigenicity and stemness of cancer cells
Published in Cell research (01-06-2017)“…DNA double-strand breaks (DSBs) are traditionally associated with cancer through their abilities to cause chro- mosomal instabilities or gene mutations. Here…”
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ATM Regulation of the Cohesin Complex Is Required for Repression of DNA Replication and Transcription in the Vicinity of DNA Double-Strand Breaks
Published in Molecular cancer research (01-03-2023)“…Multiple members of the cohesin complex are involved in the regulation of DNA replication and transcription in the vicinity of DNA double-strand breaks and…”
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Participation of ATM, SMG1, and DDX5 in a DNA Damage-Induced Alternative Splicing Pathway
Published in Radiation research (01-04-2023)“…Altered cellular responses to DNA damage can contribute to cancer development, progression, and therapeutic resistance. Mutations in key DNA damage response…”
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4
Prolactin Induction of Insulin Gene Transcription: Roles of Glucose and Signal Transducer and Activator of Transcription 5
Published in Endocrinology (Philadelphia) (01-07-2001)“…Abstract GH and PRL stimulate insulin production in pancreatic β-cells through induction of insulin gene transcription. The transcriptional effects of GH are…”
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Structure of the CD59-Encoding Gene: Further Evidence of a Relationship to Murine Lymphocyte Antigen Ly-6 Protein
Published in Proceedings of the National Academy of Sciences - PNAS (01-09-1992)“…The gene for CD59 [membrane inhibitor of reactive lysis (MIRL), protectin], a phosphatidylinositol-linked surface glycoprotein that regulates the formation of…”
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Prolactin Induction of Insulin Gene Transcription: Roles of Glucose and Signal Transducer and Activator of Transcription 51
Published in Endocrinology (Philadelphia) (01-07-2001)“…GH and PRL stimulate insulin production in pancreatic β-cells through induction of insulin gene transcription. The transcriptional effects of GH are mediated…”
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Avian cardiac tropomyosin gene produces tissue-specific isoforms through alternative RNA splicing
Published in Journal of muscle research and cell motility (01-02-1992)Get full text
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The structure of the urokinase-type plasminogen activator receptor gene
Published in Blood (15-08-1994)“…The cellular receptor for urokinase-type plasminogen activator (uPAR) is a glycosylphosphatidylinositol (GPI)-anchored membrane protein that plays a central…”
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Comparison of human and Xenopus GATA-2 promoters
Published in Gene (14-11-1996)“…GATA proteins comprise a family of transcription factors that are required for appropriate development of hematopoietic lineages. In order to understand the…”
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Characterization of the DNase I Hypersensitive Site 3 of the Human β Globin Gene Domain
Published in Blood (15-05-1993)“…The members of the human β globin gene family are flanked by strong DNase I hypersensitive sites. The collection of sites 5′ to the ϵ globin gene is able to…”
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Isolation and Characterization of the Genomic Human CD7 Gene: Structural Similarity with the Murine Thy-1 Gene
Published in Proceedings of the National Academy of Sciences - PNAS (15-01-1991)“…The human CD7 molecule is a 40-kDa member of the immunoglobulin gene superfamily that is expressed on T-lymphoid and myeloid precursors in fetal liver and bone…”
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Characterization of human CD7 transgenic mice
Published in The Journal of immunology (1950) (01-09-1995)“…CD7 is a 40-kDa transmembrane glycoprotein member of the lg gene superfamily expressed on most peripheral blood T lymphocytes and NK cells. CD7 is also…”
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The mouseCD7 gene: Identification of a new element common to the humanCD7 and mouseThy-1 promoters
Published in Immunogenetics (New York) (01-03-1996)Get full text
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Genomic Structure and Chromosomal Localization of the Novel ETS Factor, PE-2 (ERF)
Published in Genomics (San Diego, Calif.) (01-06-1997)“…The members of the ETS family of transcription factors are grouped because they share a highly conserved DNA binding domain. These factors are involved in…”
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The mouse CD7 gene: identification of a new element common to the human CD7 and mouse Thy-1 promoters
Published in Immunogenetics (New York) (01-01-1996)“…Human CD7 (hCD7) is a 40 000 Mr member of the immunoglobulin gene superfamily that is expressed early in natural killer (NK) and T-lymphocyte development. CD7…”
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Avian tropomyosin gene expression
Published in Nucleic acids research (11-03-1989)“…Sequence analysis of overlapping fragments from a quail genomic library has revealed a tropomyosin gene consisting of 13 exons spaced over about 18 kilobase…”
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