Search Results - "Fleck, Julia L."

Physiological and socioeconomic characteristics predict COVID-19 mortality and resource utilization in Brazil by Wollenstein-Betech, Salomón, Silva, Amanda A B, Fleck, Julia L, Cassandras, Christos G, Paschalidis, Ioannis Ch

“…Given the severity and scope of the current COVID-19 pandemic, it is critical to determine predictive features of COVID-19 mortality and medical resource usage…”
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Adjuvant therapeutic strategy decision support for an elderly population with localized breast cancer: A monocentric cohort retrospective study by Fleck, Julia L, Hooijenga, Daniëlle, Phan, Raksmey, Xie, Xiaolan, Augusto, Vincent, Heudel, Pierre-Etienne

“…Guidelines for the management of elderly patients with early breast cancer are scarce. Additional adjuvant systemic treatment to surgery for early breast…”
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Predicting drug sensitivity of cancer cells based on DNA methylation levels by Miranda, Sofia P, Baião, Fernanda A, Fleck, Julia L, Piccolo, Stephen R

“…Cancer cell lines, which are cell cultures derived from tumor samples, represent one of the least expensive and most studied preclinical models for drug…”
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Data-Driven Identification of Biomarkers for In Situ Monitoring of Drug Treatment in Bladder Cancer Organoids by Becker, Lucas, Fischer, Felix, Fleck, Julia L., Harland, Niklas, Herkommer, Alois, Stenzl, Arnulf, Aicher, Wilhelm K., Schenke-Layland, Katja, Marzi, Julia

“…Three-dimensional (3D) organoid culture recapitulating patient-specific histopathological and molecular diversity offers great promise for precision medicine…”
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Integrating mutation and gene expression cross-sectional data to infer cancer progression by Fleck, Julia L, Pavel, Ana B, Cassandras, Christos G

“…A major problem in identifying the best therapeutic targets for cancer is the molecular heterogeneity of the disease. Cancer is often caused by an accumulation…”
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No-shows in appointment scheduling – a systematic literature review by Dantas, Leila F., Fleck, Julia L., Cyrino Oliveira, Fernando L., Hamacher, Silvio

“…•The findings of 105 studies on no-show in appointment scheduling are synthetized.•The main determinants of no-show are high lead time and prior no-show…”
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Adaptive Quasi-Dynamic Traffic Light Control by Fleck, Julia L., Cassandras, Christos G., Yanfeng Geng

“…We consider the traffic light control problem for a single intersection modeled as a stochastic hybrid system. We study a quasi-dynamic policy based on partial…”
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A mixed integer programming approach to the patient admission scheduling problem by Bastos, Leonardo S.L., Marchesi, Janaina F., Hamacher, Silvio, Fleck, Julia L.

“…•The static offline operational Patient Admission Scheduling Problem is addressed.•An exact method is proposed to solve a mixed integer programming…”
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Prediction of deep molecular response in chronic myeloid leukemia using supervised machine learning models by Zad, Zahra, Bonecker, Simone, Wang, Taiyao, Zalcberg, Ilana, Stelzer, Gustavo T., Sabioni, Bruna, Gutiyama, Luciana Mayumi, Fleck, Julia L., Paschalidis, Ioannis Ch

“…•Predicting deep molecular response to imatinib treatment for Chronic Myeloid Leukemia.•Leveraging machine learning methods.•Utilizing data from a developing…”
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Optimal design of personalized prostate cancer therapy using Infinitesimal Perturbation Analysis by Fleck, Julia L., Cassandras, Christos G.

“…The standard treatment for advanced prostate cancer is hormone therapy in the form of continuous androgen suppression (CAS), which unfortunately frequently…”
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A pan-cancer analysis of progression mechanisms and drug sensitivity in cancer cell lines by Fleck, Julia L, Pavel, Ana B, Cassandras, Christos G

“…Biomarker discovery involves identifying genetic abnormalities within a tumor. However, one of the main challenges in defining such therapeutic targets is…”
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A stochastic programming approach to the physician staffing and scheduling problem by Marchesi, Janaina F., Hamacher, Silvio, Fleck, Julia L.

“…•Integrated solution for physician staffing and scheduling in Emergency Departments.•Two-stage stochastic model with fixed recourse minimizes patient queue…”
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Abstract 5486: Time-dependent mathematical modeling of genetic alterations in acute myeloid leukemia by Fleck, Julia L., Meirim, Matheus O., Pavel, Ana B., Gutiyama, Luciana M., Zalcberg, Ilana R.

“…Acute myeloid leukemia (AML) is a complex, aggressive type of neoplasia characterized by mutations in myeloid stem cells. Here we perform a hierarchical and…”
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Adjuvant therapeutic strategy decision support for an elderly population with localized breast cancer: A monocentric cohort retrospective study by Julia L Fleck, Daniëlle Hooijenga, Raksmey Phan, Xiaolan Xie, Vincent Augusto, Pierre-Etienne Heudel

“…Guidelines for the management of elderly patients with early breast cancer are scarce. Additional adjuvant systemic treatment to surgery for early breast…”
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Topics in perturbation analysis for Stochastic Hybrid Systems by Fleck, Julia L

“…Control and optimization of Stochastic Hybrid Systems (SHS) constitute increasingly active fields of research. However, the size and complexity of SHS…”
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Personalized cancer therapy design: Robustness vs. optimality by Fleck, Julia L., Cassandras, Christos G.

“…Intermittent Androgen Suppression (IAS) is a treatment strategy for delaying or even preventing time to relapse of advanced prostate cancer. IAS consists of…”
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Personalized Cancer Therapy Design: Robustness vs. Optimality by Fleck, Julia L, Cassandras, Christos G

“…Intermittent Androgen Suppression (IAS) is a treatment strategy for delaying or even preventing time to relapse of advanced prostate cancer. IAS consists of…”
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Infinitesimal Perturbation Analysis for Personalized Cancer Therapy Design by Fleck, Julia L, Cassandras, Christos G

“…We use a Stochastic Hybrid Automaton (SHA) model of prostate cancer evolution under intermittent androgen suppression (IAS) to study a threshold-based policy…”
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Infinitesimal Perturbation Analysis for Quasi-Dynamic Traffic Light Controllers by Fleck, Julia L, Cassandras, Christos G

“…We consider the traffic light control problem for a single intersection modeled as a stochastic hybrid system. We study a quasi-dynamic policy based on partial…”
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Topics in perturbation analysis for Stochastic Hybrid Systems by Fleck, Julia L

“…Control and optimization of Stochastic Hybrid Systems (SHS) constitute increasingly active fields of research. However, the size and complexity of SHS…”
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