Hirudin therapy and blood coagulability

The changes in blood coagulative properties, which occur in the treatment with medical leeches, were studied in 57 patients with coronary heart, rheumatic and chronic pulmonary diseases. Hirudin therapy was established to affect blood coagulation. The leech salina penetrated into the skin wound to b...

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Bibliographic Details
Published in:	Kardiologiia Vol. 32; no. 5; p. 79
Main Authors:	Isakhanian, G S, Tumasian, K S, Barsegian, Z E, Mkrtchian, L S, Karapetian, A K, Fldzhian, N G
Format:	Journal Article
Language:	Russian
Published:	Russia (Federation) 01-05-1992
Subjects:	Blood Coagulation - drug effects Cardiovascular Diseases - therapy Coronary Disease - therapy Hirudin Therapy Hirudins - pharmacology Humans Middle Aged Pulmonary Heart Disease - therapy Rheumatic Heart Disease - therapy
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Summary:	The changes in blood coagulative properties, which occur in the treatment with medical leeches, were studied in 57 patients with coronary heart, rheumatic and chronic pulmonary diseases. Hirudin therapy was established to affect blood coagulation. The leech salina penetrated into the skin wound to block hemostasis. Having entered the circulating blood, some part of the saliva normalized its impaired coagulative properties. The correction of the above abnormalities and related bleeding indicate it beneficial to use hirudin therapy in secondary coagulopathies and circulatory decompensation.
ISSN:	0022-9040