Search Results - "Flaws, A."
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The epigenetic impacts of endocrine disruptors on female reproduction across generations
Published in Biology of reproduction (01-09-2019)“…Humans and animals are repeatedly exposed to endocrine disruptors, many of which are ubiquitous in the environment. Endocrine disruptors interfere with hormone…”
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Endocrine Disruptors in Water and Their Effects on the Reproductive System
Published in International journal of molecular sciences (12-03-2020)“…Anthropogenic contaminants in water can impose risks to reproductive health. Most of these compounds are known to be endocrine disrupting chemicals (EDCs)…”
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EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
Published in Endocrine reviews (01-12-2015)“…The Endocrine Society's first Scientific Statement in 2009 provided a wake-up call to the scientific community about how environmental endocrine-disrupting…”
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Evidence for bisphenol A-induced female infertility: review (2007–2016)
Published in Fertility and sterility (15-09-2016)“…We summarized the scientific literature published from 2007 to 2016 on the potential effects of bisphenol A (BPA) on female fertility. We focused on overall…”
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Executive Summary to EDC-2: The Endocrine Society's Second Scientific Statement on Endocrine-Disrupting Chemicals
Published in Endocrine reviews (01-12-2015)“…This Executive Summary to the Endocrine Society's second Scientific Statement on environmental endocrine-disrupting chemicals (EDCs) provides a synthesis of…”
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Exposure to endocrine disruptors during adulthood: consequences for female fertility
Published in Journal of endocrinology (01-06-2017)“…Endocrine disrupting chemicals are ubiquitous chemicals that exhibit endocrine disrupting properties in both humans and animals. Female reproduction is an…”
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Prenatal Exposure to Di(2-Ethylhexyl) Phthalate Causes Long-Term Transgenerational Effects on Female Reproduction in Mice
Published in Endocrinology (Philadelphia) (01-02-2018)“…Abstract Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer in many consumer products. Although DEHP is a known endocrine disruptor, little is known about the…”
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Prenatal exposure to an environmentally relevant phthalate mixture disrupts reproduction in F1 female mice
Published in Toxicology and applied pharmacology (01-03-2017)“…Phthalates are used in a large variety of products, such as building materials, medical devices, and personal care products. Most previous studies on the…”
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Bisphenol a and reproductive health: update of experimental and human evidence, 2007-2013
Published in Environmental health perspectives (01-08-2014)“…In 2007, an expert panel reviewed associations between bisphenol A (BPA) exposure and reproductive health outcomes. Since then, new studies have been conducted…”
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Bisphenol A down-regulates rate-limiting Cyp11a1 to acutely inhibit steroidogenesis in cultured mouse antral follicles
Published in Toxicology and applied pharmacology (01-09-2013)“…Bisphenol A (BPA) is the backbone of polycarbonate plastic products and the epoxy resin lining of aluminum cans. Previous studies have shown that exposure to…”
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Di(2-ethylhexyl) phthalate inhibits antral follicle growth, induces atresia, and inhibits steroid hormone production in cultured mouse antral follicles
Published in Toxicology and applied pharmacology (01-04-2015)“…Di(2-ethylhexyl) phthalate (DEHP) is a ubiquitous environmental toxicant found in consumer products that causes ovarian toxicity. Antral follicles are the…”
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Endocrine-disrupting chemicals in ovarian function: effects on steroidogenesis, metabolism and nuclear receptor signaling
Published in Reproduction (Cambridge, England) (01-11-2011)“…Endocrine-disrupting chemicals (EDCs) are exogenous agents with the ability to interfere with processes regulated by endogenous hormones. One such process is…”
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Maternal phthalate and phthalate alternative metabolites and urinary biomarkers of estrogens and testosterones across pregnancy
Published in Environment international (01-10-2021)“…•Cross-pregnancy urinary sum estrogens & testosterones (E&T) mirror blood patterns.•Plasticizer phthalates/replacements associated with increased sum…”
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Urinary bisphenol A concentrations and early reproductive health outcomes among women undergoing IVF
Published in Human reproduction (Oxford) (01-12-2012)“…STUDY QUESTION In women undergoing IVF, are urinary bisphenol A (BPA) concentrations associated with ovarian response and early reproductive outcomes,…”
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Free Fatty Acids Rewire Cancer Metabolism in Obesity-Associated Breast Cancer via Estrogen Receptor and mTOR Signaling
Published in Cancer research (Chicago, Ill.) (15-05-2019)“…Obesity is a risk factor for postmenopausal estrogen receptor alpha (ERα)-positive (ER ) breast cancer. Molecular mechanisms underlying factors from plasma…”
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Bisphenol A impairs follicle growth, inhibits steroidogenesis, and downregulates rate-limiting enzymes in the estradiol biosynthesis pathway
Published in Toxicological sciences (01-01-2011)“…Bisphenol A (BPA) is used as the backbone for plastics and epoxy resins, including various food and beverage containers. BPA has also been detected in 95% of…”
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Di (2-ethylhexyl) phthalate inhibits growth of mouse ovarian antral follicles through an oxidative stress pathway
Published in Toxicology and applied pharmacology (15-01-2012)“…Di (2-ethylhexyl) phthalate (DEHP) is a plasticizer that has been shown to inhibit growth of mouse antral follicles, however, little is known about the…”
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Urinary phthalate metabolite concentrations and serum hormone levels in pre- and perimenopausal women from the Midlife Women’s Health Study
Published in Environment international (01-11-2021)“…•Phthalate metabolites were positively associated with estradiol levels in midlife women.•Phthalate metabolites were positively associated with testosterone…”
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The role of the aryl hydrocarbon receptor in the female reproductive system
Published in Biochemical pharmacology (15-02-2009)“…In recent years, many studies have emphasized how changes in aryl hydrocarbon receptor (AHR)-mediated gene expression result in biological effects, raising…”
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Ovarian volume partially explains associations of phthalate biomarkers with anti-Müllerian hormone and estradiol in midlife women
Published in Environment international (01-02-2023)“…Women are ubiquitously exposed to endocrine disruptors, including phthalates. Ovarian follicles undergoing folliculogenesis (indirectly measured by ovarian…”
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