Search Results - "Flanigan, Patrick M"

Cross-activating c-Met/β1 integrin complex drives metastasis and invasive resistance in cancer by Jahangiri, Arman, Nguyen, Alan, Chandra, Ankush, Sidorov, Maxim K., Yagnik, Garima, Rick, Jonathan, Han, Sung Won, Chen, William, Flanigan, Patrick M., Schneidman-Duhovny, Dina, Mascharak, Smita, De Lay, Michael, Imber, Brandon, Park, Catherine C., Matsumoto, Kunio, Lu, Kan, Bergers, Gabriele, Sali, Andrej, Weiss, William A., Aghi, Manish K.

“…The molecular underpinnings of invasion, a hallmark of cancer, have been defined in terms of individual mediators but crucial interactions between these…”
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Convection-enhanced delivery in glioblastoma: a review of preclinical and clinical studies by Jahangiri, Arman, Chin, Aaron T, Flanigan, Patrick M, Chen, Rebecca, Bankiewicz, Krystof, Aghi, Manish K

“…Glioblastoma is the most common malignant brain tumor, and it carries an extremely poor prognosis. Attempts to develop targeted therapies have been hindered…”
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Effect of cultivar on phenolic levels, anthocyanin composition, and antioxidant properties in purple basil (Ocimum basilicum L.) by Flanigan, Patrick M., Niemeyer, Emily D.

“…•Purple basil cultivars vary in chemical composition and antioxidant properties.•Anthocyanin and phenolic acid composition varies significantly among…”
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Growth hormone and prolactin-staining tumors causing acromegaly: a retrospective review of clinical presentations and surgical outcomes by Rick, Jonathan, Jahangiri, Arman, Flanigan, Patrick M, Chandra, Ankush, Kunwar, Sandeep, Blevins, Lewis, Aghi, Manish K

“…Acromegaly results in disfiguring growth and numerous medical complications. This disease is typically caused by growth hormone (GH)-secreting pituitary…”
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The association between bone mineral density and proximal junctional kyphosis in adult spinal deformity: a systematic review and meta-analysis by Chen, Jeffrey W, McCandless, Martin G, Bhandarkar, Archis R, Flanigan, Patrick M, Lakomkin, Nikita, Mikula, Anthony L, Michalopoulos, Giorgos D, Bydon, Mohamad

“…Proximal junctional kyphosis (PJK) is a complication of surgical management for adult spinal deformity (ASD) with a multifactorial etiology. Many risk factors…”
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Connectivity of the human insula: A cortico-cortical evoked potential (CCEP) study by Dionisio, Sasha, Mayoglou, Lazarus, Cho, Sung-Min, Prime, David, Flanigan, Patrick M., Lega, Bradley, Mosher, John, Leahy, Richard, Gonzalez-Martinez, Jorge, Nair, Dileep

“…The human insula is increasingly being implicated as a multimodal functional network hub involved in a large variety of complex functions. Due to its…”
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From bench to bedside: trends in National Institutes of Health funding for neurosurgeons from 1991 to 2015 by Jahangiri, Arman, Flanigan, Patrick M, Arnush, Maxine, Chandra, Ankush, Rick, Jonathan W, Choi, Sarah, Chou, Alvin, Berger, Mitchel S, Aghi, Manish K

“…Neurosurgeons play an important role in advancing medicine through research, the funding of which is historically linked to the National Institutes of Health…”
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Interbody cages versus structural bone grafts in lumbar arthrodesis: a systematic review and meta-analysis by Johnson, Sarah E, Michalopoulos, Giorgos D, Flanigan, Patrick M, Katsos, Konstantinos, Ibrahim, Sufyan, Freedman, Brett A, Bydon, Mohamad

“…The role of interbodies in lumbar arthrodesis has been insufficiently supported by evidence, impacting clinical decision-making and occasionally insurance…”
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Postoperative Delirium in Glioblastoma Patients: Risk Factors and Prognostic Implications by Flanigan, Patrick M, Jahangiri, Arman, Weinstein, Drew, Dayani, Fara, Chandra, Ankush, Kanungo, Ishan, Choi, Sarah, Sankaran, Sujatha, Molinaro, Annette M, McDermott, Michael W, Berger, Mitchel S, Aghi, Manish K

“…Abstract BACKGROUND Delirium is a postoperative neurological morbidity in glioblastoma whose risk factors, incidence, and prognostic implications remain…”
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A cross-sectional study of neurosurgical department chairs in the United States by Flanigan, Patrick M, Jahangiri, Arman, Golubovsky, Joshua L, Karnuta, Jaret M, May, Francis J, Berger, Mitchel S, Aghi, Manish K

“…OBJECTIVEThe position of neurosurgery department chair undergoes constant evolution as the health care landscape changes. The authors' aim in this paper was to…”
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Color Vision Impairment Differentiates Alzheimer Dementia From Dementia With Lewy Bodies by Flanigan, Patrick M., Khosravi, Mitra A., Leverenz, James B., Tousi, Babak

“…Objective: Dementia with Lewy bodies (DLB) is frequently misdiagnosed for Alzheimer dementia (AD), especially in its earlier stages. We characterized color…”
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Developing an Algorithm for Optimizing Care of Elderly Patients With Glioblastoma by Flanigan, Patrick M, Jahangiri, Arman, Kuang, Ruby, Truong, Albert, Choi, Sarah, Chou, Alvin, Molinaro, Annette M, McDermott, Michael W, Berger, Mitchel S, Aghi, Manish K

“…Abstract BACKGROUND Elderly patients with glioblastoma have an especially poor prognosis; optimizing their medical and surgical care remains of paramount…”
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Improved Survival with Decreased Wait Time to Surgery in Glioblastoma Patients Presenting with Seizure by Flanigan, Patrick M, Jahangiri, Arman, Kuang, Ruby, Truong, Albert, Choi, Sarah, Chou, Alvin, Rick, Jonathan W, Chang, Susan M, Molinaro, Annette M, McDermott, Michael W, Berger, Mitchel S, Aghi, Manish K

“…Abstract BACKGROUND Preoperative seizure is reported to confer favorable prognosis in glioblastoma patients, but studies to date have not investigated how…”
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Operative Treatment of Bertolotti Syndrome: Resection Versus Fusion by Mikula, Anthony L, Lakomkin, Nikita, Ransom, Ryan C, Flanigan, Patrick M, Waksdahl, Laura A, Pennington, Zach, Sharma, Manish S, Elder, Benjamin D, Fogelson, Jeremy L

“…To compare the outcomes of joint resection versus fusion in patients who undergo operative treatment for Bertolotti syndrome. A chart review identified…”
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Clinical and Imaging Characteristics Associated with Color Vision Impairment in Lewy Body Disease by Unger, Robert H, Flanigan, Patrick M, Khosravi, Mitra, Leverenz, James B, Tousi, Babak

“…Color vision impairment (CVI) has been reported in dementia with Lewy bodies (DLB) and prodromal Lewy body disease (pro-LBD). In order to better characterize…”
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Regional improvements in lumbosacropelvic Hounsfield units following teriparatide treatment by Flanigan, Patrick M., Mikula, Anthony L., Peters, Pierce A., Oushy, Soliman, Fogelson, Jeremy L., Bydon, Mohamad, Freedman, Brett A., Sebastian, Arjun S., Currier, Bradford L., Nassr, Ahmad, Kennel, Kurt A., Anderson, Paul A., Polly, David W., Elder, Benjamin D.

“…OBJECTIVEOpportunistic Hounsfield unit (HU) determination from CT imaging has been increasingly used to estimate bone mineral density (BMD) in conjunction with…”
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Update on the management of recurrent Cushing's disease by Rutkowski, Martin J, Flanigan, Patrick M, Aghi, Manish K

“…After transsphenoidal surgery, Cushing's disease (CD) shows excellent long-term remission rates, but it may recur and pose a therapeutic challenge. Findings in…”
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Adaptation to antiangiogenic therapy in neurological tumors by Flanigan, Patrick M, Aghi, Manish K

“…Because tumors require a vascular supply for their survival and growth, angiogenesis is considered an important therapeutic target in most human cancers…”
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Combined Middle Fossa and Transmastoid Approach for Resection of Petrous Temporal Meningioma With Facial Nerve Reanimation by Interposition Grafting: 2-Dimensional Operative Video by Rinaldo, Lorenzo, Flanigan, Patrick M, Nassiri, Ashley M, Neff, Brian A, Van Gompel, Jamie J

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Lower Hounsfield Units at the Upper Instrumented Vertebrae are Significantly Associated With Proximal Junctional Kyphosis and Failure Near the Thoracolumbar Junction by Mikula, Anthony L, Fogelson, Jeremy L, Lakomkin, Nikita, Flanigan, Patrick M, Pinter, Zachariah W, Doan, Matthew K, Bydon, Mohamad, Nassr, Ahmad, Freedman, Brett, Sebastian, Arjun S, Abode-Iyamah, Kingsley, Anderson, Paul A, Elder, Benjamin D

“…Abstract BACKGROUND Low bone mineral density (BMD) on dual energy x-ray absorptiometry (DXA) is likely a risk factor for proximal junctional kyphosis (PJK) and…”
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