Search Results - "Flanagan, Michael"

Novel charged and hydrophilized polybenzimidazole (PBI) membranes for forward osmosis by Flanagan, Michael F., Escobar, Isabel C.

“…Polybenzimidazole (PBI) is a material with excellent chemical resistance, and thermal and mechanical stabilities. However, significant drawbacks of PBI that…”
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How to design and implement a Group Poem activity by Jung, Diane, Chugh, Natasha, Stephens, Mark, Blazek, Mary, Flanagan, Michael P, Chisolm, Margaret S

“…Museum-based learning activities provide interactive and innovative ways to integrate the arts and humanities into medical education. Like other museum-based…”
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Pass/No-Pass Step 1: Navigating the Changing Path to Medical Education by Higgins, Ryan C, Flanagan, Michael P

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Evolving Trends in Surgical Management of Breast Cancer: An Analysis of 30 Years of Practice Changing Papers by Keelan, Stephen, Flanagan, Michael, Hill, Arnold D. K.

“…The management of breast cancer has evolved into a multidisciplinary evidence-based surgical speciality, with emphasis on conservative surgery. A number of…”
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A State-of-the-Art Review of Structural Testing of Tidal Turbine Blades by Munaweera Thanthirige, Tenis Ranjan, Goggins, Jamie, Flanagan, Michael, Finnegan, William

“…Over the last two decades, the tidal energy industry has laid the groundwork for creating commercially viable tidal power generation projects to strengthen…”
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C3 Glomerulopathy: Clinicopathologic Features and Predictors of Outcome by Medjeral-Thomas, Nicholas R, O'Shaughnessy, Michelle M, O'Regan, John A, Traynor, Carol, Flanagan, Michael, Wong, Limy, Teoh, Chia Wei, Awan, Atif, Waldron, Mary, Cairns, Tom, O'Kelly, Patrick, Dorman, Anthony M, Pickering, Matthew C, Conlon, Peter J, Cook, H Terence

“…The term C3 glomerulopathy describes renal disorders characterized by the presence of glomerular deposits composed of C3 in the absence of significant amounts…”
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Mapping Student-Generated Learning Objectives Against USMLE Core Content by Yoder, Lauren Mica, Flanagan, Michael, Thompson, Britta, Stephens, Mark

“…Purpose: To compare the content covered by student-generated, case-based, learning objectives with United States Medical Licensing Exams (USMLE) core-content…”
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Phase I study of the anti-endothelin B receptor antibody-drug conjugate DEDN6526A in patients with metastatic or unresectable cutaneous, mucosal, or uveal melanoma by Sandhu, Shahneen, McNeil, Catriona M., LoRusso, Patricia, Patel, Manish R., Kabbarah, Omar, Li, Chunze, Sanabria, Sandra, Flanagan, W. Michael, Yeh, Ru-Fang, Brunstein, Flavia, Nazzal, Denise, Hicks, Rodney, Lemahieu, Vanessa, Meng, Raymond, Hamid, Omid, Infante, Jeffrey R.

“…Summary Background Endothelin B receptor (ET B R) is involved in melanoma pathogenesis and is overexpressed in metastatic melanoma. The antibody-drug conjugate…”
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The Role of the Craniocervical Junction in Craniospinal Hydrodynamics and Neurodegenerative Conditions by Flanagan, Michael F.

“…The craniocervical junction (CCJ) is a potential choke point for craniospinal hydrodynamics and may play a causative or contributory role in the pathogenesis…”
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A Standardized and Regionalized Network of Care for Cardiogenic Shock by Tehrani, Behnam N, Sherwood, Matthew W, Rosner, Carolyn, Truesdell, Alexander G, Ben Lee, Seiyon, Damluji, Abdulla A, Desai, Mehul, Desai, Shashank, Epps, Kelly C, Flanagan, Michael C, Howard, Edward, Ibrahim, Nasrien, Kennedy, Jamie, Moukhachen, Hala, Psotka, Mitchell, Raja, Anika, Saeed, Ibrahim, Shah, Palak, Singh, Ramesh, Sinha, Shashank S, Tang, Daniel, Welch, Timothy, Young, Karl, deFilippi, Christopher R, Speir, Alan, O'Connor, Christopher M, Batchelor, Wayne B

“…The benefits of standardized care for cardiogenic shock (CS) across regional care networks are poorly understood. The authors compared the management and…”
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Cross Campus Perceptions of the Role of a Novel Regional Medical Campus by Higgins, Ryan, Levine, Marc, Flanagan, Michael, Williams, Emmanuelle, Higgins, Jack, Thompson, Britta, Ropson, Ira

“…Regional medical campuses (RMCs) were initially established to address a projected physician shortage and have gained popularity throughout the country in also…”
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Umbilical mesenchymal stem cell-derived extracellular vesicles as enzyme delivery vehicle to treat Morquio A fibroblasts by Flanagan, Michael, Pathak, Isha, Gan, Qi, Winter, Linda, Emnet, Ryan, Akel, Salem, Montaño, Adriana M

“…Mucopolysaccharidosis IVA (Morquio A syndrome) is a lysosomal storage disease caused by the deficiency of enzyme N-acetylgalactosamine-6-sulfate sulfatase…”
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Development of a Wellness Curriculum at a New Regional Campus: A Pilot Study by Edel, Katelyn, Flanagan, Michael, Qiu, Juan, Gardner, Jacqueline

“…Background: Burnout is a critical issue that is increasingly prevalent among healthcare professionals. Several studies suggest that the decline in mental…”
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ApoB siRNA-induced Liver Steatosis is Resistant to Clearance by the Loss of Fatty Acid Transport Protein 5 (Fatp5) by Ason, Brandon, Castro-Perez, Jose, Tep, Samnang, Stefanni, Alice, Tadin-Strapps, Marija, Roddy, Thomas, Hankemeier, Thomas, Hubbard, Brian, Sachs, Alan B., Michael Flanagan, W., Kuklin, Nelly A., Mitnaul, Lyndon J.

“…The association between hypercholesterolemia and elevated serum apolipoprotein B (APOB) has generated interest in APOB as a therapeutic target for patients at…”
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Nucleobase and Ribose Modifications Control Immunostimulation by a MicroRNA-122-mimetic RNA by Peacock, Hayden, Fucini, Raymond V, Jayalath, Prasanna, Ibarra-Soza, José M, Haringsma, Henry J, Flanagan, W. Michael, Willingham, Aarron, Beal, Peter A

“…Immune stimulation is a significant hurdle in the development of effective and safe RNA interference therapeutics. Here, we address this problem in the context…”
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Hydrogel Delivery Device for the In Vitro and In Vivo Sustained Release of Active rhGALNS Enzyme by Flanagan, Michael, Gan, Qi, Sheth, Saahil, Schafer, Rachel, Ruesing, Samuel, Winter, Linda E, Toth, Karoly, Zustiak, Silviya P, Montaño, Adriana M

“…Morquio A disease is a genetic disorder resulting in N-acetylgalactosamine-6-sulfate sulfatase (GALNS) deficiency, and patients are currently treated with…”
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Single-stranded microRNA mimics by Chorn, Guillaume, Klein-McDowell, Molly, Zhao, Lihong, Saunders, Matthew A, Flanagan, W Michael, Willingham, Aarron T, Lim, Lee P

“…miRNAs are ∼22-nt RNAs that bind to the Argonaute family of proteins and have important regulatory roles in plants and animals. Here, we show that miRNAs…”
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Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5'-terminal phosphorylation both in vitro and in vivo by Kenski, Denise M, Cooper, Abby J, Li, Jenny J, Willingham, Aarron T, Haringsma, Henry J, Young, Tracy A, Kuklin, Nelly A, Jones, Jeffrey J, Cancilla, Mark T, McMasters, Daniel R, Mathur, Melina, Sachs, Alan B, Flanagan, W. Michael

“…Small interfering RNAs (siRNAs) are short, double-stranded RNAs that use the endogenous RNAi pathway to mediate gene silencing. Phosphorylation facilitates…”
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Contemporary approach to cardiogenic shock care: a state-of-the-art review by Mehta, Aditya, Vavilin, Ilan, Nguyen, Andrew H, Batchelor, Wayne B, Blumer, Vanessa, Cilia, Lindsey, Dewanjee, Aditya, Desai, Mehul, Desai, Shashank S, Flanagan, Michael C, Isseh, Iyad N, Kennedy, Jamie L W, Klein, Katherine M, Moukhachen, Hala, Psotka, Mitchell A, Raja, Anika, Rosner, Carolyn M, Shah, Palak, Tang, Daniel G, Truesdell, Alexander G, Tehrani, Behnam N, Sinha, Shashank S

“…Cardiogenic shock (CS) is a time-sensitive and hemodynamically complex syndrome with a broad spectrum of etiologies and clinical presentations. Despite…”
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mRNA knockdown by single strand RNA is improved by chemical modifications by Haringsma, Henry J, Li, Jenny J, Soriano, Ferdie, Kenski, Denise M, Flanagan, W Michael, Willingham, Aarron T

“…While RNAi has traditionally relied on RNA duplexes, early evaluation of siRNAs demonstrated activity of the guide strand in the absence of the passenger…”
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