Search Results - "Flaherty, Meghan M"
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DEPLETED AND NATURAL URANIUM: CHEMISTRY AND TOXICOLOGICAL EFFECTS
Published in Journal of toxicology and environmental health. Part B, Critical reviews (01-07-2004)“…Depleted uranium (DU) is a by-product from the chemical enrichment of naturally occurring uranium. Natural uranium is comprised of three radioactive isotopes:…”
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Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers
Published in Cancer discovery (01-09-2017)“…Despite an improving therapeutic landscape, significant challenges remain in treating the majority of patients with advanced ovarian or renal cancer. We…”
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Nonclinical Evaluation of GMA161-An Antihuman CD16 (FcγRIII) Monoclonal Antibody for Treatment of Autoimmune Disorders in CD16 Transgenic Mice
Published in Toxicological sciences (2012)“…Fc receptors are a critical component of the innate immune system responsible for the recognition of cross-linked antibodies and the subsequent clearance of…”
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An investigation of hemopexin redox properties by spectroelectrochemistry: biological relevance for heme uptake
Published in Biometals (01-06-2008)“…Hemopexin (HPX) has two principal roles: it sequesters free heme in vivo for the purpose of preventing the toxic effects of this moiety, which is largely due…”
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Heterogeneity of Toxicant Response: Sources of Human Variability
Published in Toxicological sciences (01-11-2003)“…While risk assessment models attempt to predict human risk to toxicant exposure, in many cases these models cannot account for the wide variety of human…”
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Synthesis and in vitro antioxidant properties of manganese(III) β-octabromo- meso-tetrakis(4-carboxyphenyl)porphyrin
Published in Journal of inorganic biochemistry (01-07-2003)“…Manganese(III) meso-tetrakis(4-carboxypheny)porphyrin (MnTBAP) is a readily available and widely used agent to scavenge reactive oxygen species. A major…”
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