Search Results - "Flad, Hans‐Dieter"

Platelet-derived chemokines: pathophysiology and therapeutic aspects by Flad, Hans-Dieter, Brandt, Ernst

“…The identification of chemokines in blood platelets has strengthened our view of these cells as participants in immune host defense. Platelet chemokines…”
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Platelet-Derived Chemokines CXC Chemokine Ligand (CXCL)7, Connective Tissue-Activating Peptide III, and CXCL4 Differentially Affect and Cross-Regulate Neutrophil Adhesion and Transendothelial Migration by Schenk, Birgit I, Petersen, Frank, Flad, Hans-Dieter, Brandt, Ernst

“…In this study, we have examined the major platelet-derived CXC chemokines connective tissue-activating peptide III (CTAP-III), its truncation product…”
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Control of Mycobacterial Replication in Human Macrophages: Roles of Extracellular Signal-Regulated Kinases 1 and 2 and p38 Mitogen-Activated Protein Kinase Pathways by BLUMENTHAL, Antie, EHLERS, Stefan, ERNST, Martin, FLAD, Hans-Dieter, REILING, Norbert

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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A Chondroitin Sulfate Proteoglycan on Human Neutrophils Specifically Binds Platelet Factor 4 and Is Involved in Cell Activation by Petersen, Frank, Bock, Lothar, Flad, Hans-Dieter, Brandt, Ernst

“…Platelet factor 4 (PF-4), a member of the alpha-chemokine subfamily of cytokines, activates human neutrophils independently of intracellular free calcium…”
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Increased IL‐10 production during spontaneous apoptosis of monocytes by Bzowska, Malgorzata, Guzik, Krzysztof, Barczyk, Katarzyna, Ernst, Martin, Flad, Hans‐Dieter, Pryjma, Juliusz

“…Monocytes/macrophages undergo apoptosis and are in contact with apoptotic cells both in vitro and in vivo. The data show that monocytes undergoing spontaneous…”
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Human follicular dendritic cells and vascular cells produce interleukin-7: a potential role for interleukin-7 in the germinal center reaction by Kröncke, R, Loppnow, H, Flad, H D, Gerdes, J

“…Interleukin-7 (IL-7) has long been known as a potent growth factor in lymphocyte development. However, recent data obtained in vitro revealed additional…”
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Reduced T‐cell receptor CD3ζ‐chain protein and sustained CD3ε expression at the site of mycobacterial infection by Seitzer, Ulrike, Kayser, Klaus, Höhn, Hanni, Entzian, Peter, Wacker, Hans‐Heinrich, Ploetz, Sabine, Flad, Hans‐Dieter, Gerdes, Johannes, Maeurer, Markus J.

“…Summary Control of mycobacterial infection by the cellular immune system relies both on antigen‐presenting cells and on T lymphocytes. The quality of an…”
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Down-regulation of neutrophil functions by the ELR+CXC chemokine platelet basic protein by Ehlert, Jan E., Ludwig, Andreas, Grimm, Tobias A., Lindner, Buko, Flad, Hans-Dieter, Brandt, Ernst

“…The platelet-derived neutrophil-activating peptide 2 (NAP-2, 70 amino acids) belongs to the ELR+ CXC subfamily of chemokines. Similar to other members of this…”
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The CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophages by Scheuerer, Barbara, Ernst, Martin, Dürrbaum-Landmann, Iris, Fleischer, Jens, Grage-Griebenow, Evelin, Brandt, Ernst, Flad, Hans-Dieter, Petersen, Frank

“…Unstimulated monocytes rapidly undergo physiological changes resulting in programmed cell death (apoptosis) while stimuli promoting differentiation of these…”
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Components of gut bacteria as immunomodulators by Hamann, Lutz, EL-Samalouti, Volker, Ulmer, Artur J, Flad, Hans-Dieter, Rietschel, Ernst Th

“…In 1885 Louis Pasteur was the first to propose that the human immune system may be influenced by microorganisms. A large body of data has since been…”
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Platelet-derived CXC chemokines: old players in new games by Brandt, Ernst, Ludwig, Andreas, Petersen, Frank, Flad, Hans-Dieter

“…Although platelet factor 4 (PF-4) and the beta-thromboglobulin (beta-TG) proteins represent the first chemokines to be discovered, their functional roles in…”
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Biochemistry and cell biology of bacterial endotoxins by Holst, Otto, Ulmer, Artur J., Brade, Helmut, Flad, Hans-Dieter, Rietschel, Ernst Th

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Binding of lipopolysaccharide (LPS) to CHO cells does not correlate with LPS‐induced NF‐κB activation by Hamann, Lutz, Schumann, Ralf R., Flad, Hans‐Dieter, Brade, Lore, Rietschel, Ernst T., Ulmer, Artur J.

“…Activation of myeloid cells by lipopolysaccharide (LPS) is a key event in the development of gram‐negative sepsis. One crucial step within this process is the…”
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Platelet Factor 4 Inhibits Proliferation and Cytokine Release of Activated Human T Cells by Fleischer, Jens, Grage-Griebenow, Evelin, Kasper, Brigitte, Heine, Holger, Ernst, Martin, Brandt, Ernst, Flad, Hans-Dieter, Petersen, Frank

“…Platelet factor 4 (PF-4), a platelet-derived CXC chemokine, has been shown to induce the differentiation of monocytes into a subset of macrophages that lack…”
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The involvement of CD14 in the activation of human monocytes by peptidoglycan monomers by Muhvić, D, El-Samalouti, V, Flad, H D, Radosević-Stasić, B, Rukavina, D

“…Cell-wall components of Gram-positive and Gram-negative bacteria induce the production of cytokines in human peripheral blood mononuclear cells. These…”
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The CXC-Chemokine Neutrophil-Activating Peptide-2 Induces Two Distinct Optima of Neutrophil Chemotaxis by Differential Interaction With Interleukin-8 Receptors CXCR-1 and CXCR-2 by Ludwig, Andreas, Petersen, Frank, Zahn, Stefan, Götze, Otto, Schröder, Jens-Michael, Flad, Hans-Dieter, Brandt, Ernst

“…The CXC-chemokines interleukin-8 (IL-8), neutrophil-activating peptide-2 (NAP-2), and melanoma growth-stimulatory activity (MGSA) are chemoattractants with…”
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PROPERTIES OF MULTINUCLEATED GIANT CELLS IN A NEW IN VITRO MODEL FOR HUMAN GRANULOMA FORMATION by SEITZER, ULRIKE, SCHEEL-TOELLNER, DAGMAR, TOELLNER, KAI-MICHAEL, REILING, NORBERT, HAAS, HELMUT, GALLE, JÜRGEN, FLAD, HANS-DIETER, GERDES, JOHANNES

“…Multinucleated giant cells (MGCs) are a key feature of granulomas. They have been studied with respect to the mechanism and regulation of their formation, but…”
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Induction of proliferation and cytokine production in human T lymphocytes by lipopolysaccharide (LPS) by Ulmer, Artur J., Flad, Hans-Dieter, Rietschel, Th, Mattern, Taila

“…Lipopolysaccharide (LPS), also known as endotoxin, is a compound of the cell wall of Gram-negative bacteria, which has been demonstrated to induce inflammatory…”
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Platelet Factor 4-Induced Neutrophil-Endothelial Cell Interaction: Involvement of Mechanisms and Functional Consequences Different From Those Elicited by Interleukin-8 by Petersen, Frank, Bock, Lothar, Flad, Hans-Dieter, Brandt, Ernst

“…Platelet factor 4 (PF-4), a member of the CXC-subfamily of chemokines, is secreted in high amounts by activated platelets. In previous studies, we found that…”
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Fc gamma receptor I (CD64)-negative human monocytes are potent accessory cells in viral antigen-induced T cell activation and exhibit high IFN-alpha-producing capacity by Grage-Griebenow, E, Flad, H D, Ernst, M

“…Blood monocytes represent a heterogeneous cell population with respect to phenotype and function. We have previously described that a minor subset of Fcγ…”
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