Search Results - "Flørenes, Vivi Ann"

Soluble AXL as a marker of disease progression and survival in melanoma by Flem-Karlsen, Karine, Nyakas, Marta, Farstad, Inger Nina, McFadden, Erin, Wernhoff, Patrik, Jacobsen, Kari Dolven, Flørenes, Vivi Ann, Mælandsmo, Gunhild Mari

“…Receptor tyrosine kinase AXL is a one-pass transmembrane protein upregulated in cancers and associated with lower survival and therapy resistance. AXL can be…”
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High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy by Magnussen, Gry Irene, Holm, Ruth, Emilsen, Elisabeth, Rosnes, Anne Katrine Ree, Slipicevic, Ana, Flørenes, Vivi Ann

“…Notoriously resistant malignant melanoma is one of the most increasing forms of cancer worldwide; there is thus a precarious need for new treatment options…”
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AXL inhibition improves BRAF-targeted treatment in melanoma by Nyakas, Marta, Fleten, Karianne Giller, Haugen, Mads Haugland, Engedal, Nikolai, Sveen, Christina, Farstad, Inger Nina, Flørenes, Vivi Ann, Prasmickaite, Lina, Mælandsmo, Gunhild Mari, Seip, Kotryna

“…More than half of metastatic melanoma patients receiving standard therapy fail to achieve a long-term survival due to primary and/or acquired resistance. Tumor…”
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MX 2 is a novel regulator of cell cycle in melanoma cells by Juraleviciute, Marina, Pozniak, Joanna, Nsengimana, Jérémie, Harland, Mark, Randerson‐Moor, Juliette, Wernhoff, Patrik, Bassarova, Assia, Øy, Geir Frode, Trøen, Gunhild, Flørenes, Vivi Ann, Bishop, David Timothy, Herlyn, Meenhard, Newton‐Bishop, Julia, Slipicevic, Ana

“…MX2 protein is a dynamin‐like GTPase2 that has recently been identified as an interferon‐induced restriction factor of HIV‐1 and other primate lentiviruses. A…”
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Expression and clinical role of DJ-1, a negative regulator of PTEN, in ovarian carcinoma by Davidson, Ben, MD, PhD, Hadar, Rivka, MSc, Schlossberg, Anat, BSc, Sternlicht, Tamar, MSc, Slipicevic, Ana, MSc, Skrede, Martina, Risberg, Björn, MD, PhD, Flørenes, Vivi Ann, PhD, Kopolovic, Juri, MD, Reich, Reuven, PhD

“…Summary The aim of this study was to analyze the expression and clinical role of DJ-1, a negative regulator of PTEN (phosphatase and tensin homolog deleted on…”
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Immunotoxin targeting EpCAM effectively inhibits peritoneal tumor growth in experimental models of mucinous peritoneal surface malignancies by Flatmark, Kjersti, Guldvik, Ingrid J., Svensson, Hege, Fleten, Karianne G., Ann Flørenes, Vivi, Reed, Wenche, Giercksky, Karl‐Erik, Fodstad, Øystein, Andersson, Yvonne

“…Cytoreductive surgery and intraperitoneal (i.p.) chemotherapy constitute a curative treatment option in mucinous peritoneal surface malignancies of intestinal…”
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Gene Expression Signatures Differentiate Ovarian/Peritoneal Serous Carcinoma from Diffuse Malignant Peritoneal Mesothelioma by DAVIDSON, Ben, ZHEN ZHANG, KLEINBERG, Lilach, MEI LI, FLØRENES, Vivi Ann, WANG, Tian-Li, SHIH, Le-Ming

“…Purpose: Ovarian/primary peritoneal serous carcinoma (OC/PPC) and diffuse peritoneal malignant mesothelioma (DMPM) are highly aggressive tumors that are…”
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Aurora B expression in metastatic effusions from advanced-stage ovarian serous carcinoma is predictive of intrinsic chemotherapy resistance by Hetland, Thea Eline, MD, Nymoen, Dag Andre, MSc, Holth, Arild, BSc, Brusegard, Kjersti, MSc, Flørenes, Vivi Ann, PhD, Kærn, Janne, MD, PhD, Tropé, Claes G., MD, PhD, Davidson, Ben, MD, PhD

“…Summary The aim of the present study was to investigate the expression and clinical role of the aurora A and aurora B kinases in primary and metastatic serous…”
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Dacarbazine and the agonistic TRAIL receptor-2 antibody lexatumumab induce synergistic anticancer effects in melanoma by Engesæter, Birgit, Engebraaten, Olav, Flørenes, Vivi Ann, Mælandsmo, Gunhild Mari

“…Mapatumumab and lexatumumab (targeting death receptor 4 (DR4) and 5 (DR5), respectively) are agonistic TRAIL receptor antibodies that induce apoptosis in a…”
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A Three-dimensional Ex Vivo Viability Assay Reveals a Strong Correlation Between Response to Targeted Inhibitors and Mutation Status in Melanoma Lymph Node Metastases by Flørenes, Vivi Ann, Flem-Karlsen, Karine, McFadden, Erin, Bergheim, Inger Riise, Nygaard, Vigdis, Nygård, Vegard, Farstad, Inger Nina, Øy, Geir Frode, Emilsen, Elisabeth, Giller-Fleten, Karianne, Ree, Anne Hansen, Flatmark, Kjersti, Gullestad, Hans Petter, Hermann, Robert, Ryder, Truls, Wernhoff, Patrik, Mælandsmo, Gunhild Mari

“…Although clinical management of melanoma has changed considerably in recent years, intrinsic treatment resistance remains a severe problem and strategies to…”
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Expression of inhibitor-of-apoptosis protein family members in malignant mesothelioma by Kleinberg, Lilach, MSc, Lie, Agnes Kathrine, MD PhD, Flørenes, Vivi Ann, PhD, Nesland, Jahn M., MD, PhD, Davidson, Ben, MD, PhD

“…Summary Inhibitor-of-apoptosis proteins (IAPs) mediate cancer cell survival and chemoresistance. We analyzed the expressions of X-linked IAP (XIAP), survivin,…”
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HMGA2 protein expression in ovarian serous carcinoma effusions, primary tumors, and solid metastases by Hetland, Thea Eline, Holth, Arild, Kærn, Janne, Flørenes, Vivi Ann, Tropé, Claes G., Davidson, Ben

“…The objective of this study was to analyze the expression and clinical role of the high mobility group AT hook (HMGA) protein in advanced-stage serous ovarian…”
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The fatty acid binding protein 7 (FABP7) is involved in proliferation and invasion of melanoma cells by Slipicevic, Ana, Jørgensen, Kjersti, Skrede, Martina, Rosnes, Anne Katrine Ree, Trøen, Gunhild, Davidson, Ben, Flørenes, Vivi Ann

“…The molecular mechanisms underlying melanoma tumor development and progression are still not completely understood. One of the new candidates that emerged from…”
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Altered expression and activation of the nerve growth factor receptors TrkA and p75 provide the first evidence of tumor progression to effusion in breast carcinoma by DAVIDSON, Ben, REICH, Reuven, LAZAROVICI, Philip, FLØRENES, Vivi Ann, NIELSEN, Søren, NESLAND, Jahn M

“…The aim of this study was to characterize phenotypic alterations along the progression of breast carcinoma from primary tumor to pleural effusion through…”
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Expression of HLA-G in malignant mesothelioma and clinically aggressive breast carcinoma by KLEINBERG, Lilach, FLØRENES, Vivi Ann, SKREDE, Martina, HIEP PHUC DONG, NIELSEN, Søren, MCMASTER, Michael T, NESLAND, Jahn M, SHIH, Ie-Ming, DAVIDSON, Ben

“…The aim of the present study was to evaluate HLA-G expression in breast carcinoma and malignant mesothelioma (MM). Malignant breast carcinoma effusions (46)…”
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Biological effects induced by insulin‐like growth factor binding protein 3 (IGFBP‐3) in malignant melanoma by Øy, Geir Frode, Slipicevic, Ana, Davidson, Ben, Solberg Faye, Ragnar, M. Mælandsmo, Gunhild, Flørenes, Vivi Ann

“…The insulin like growth factor (IGF) signaling pathway has been shown to contribute to melanoma progression, but little is known about the role of the IGF…”
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Targeting inhibitor of apoptosis proteins in combination with dacarbazine or TRAIL in melanoma cells by Engesæter, Birgit Ø., Sathermugathevan, Menaka, Hellenes, Tina, Engebråten, Olav, Holm, Ruth, Flørenes, Vivi Ann, Mælandsmo, Gunhild M.

“…Melanoma is a highly aggressive malignant tumor with an exceptional ability to develop resistance and no curative therapy is available for patients with…”
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hvTRA, a novel TRAIL receptor agonist, induces apoptosis and sustained growth retardation in melanoma by Fleten, Karianne G, Flørenes, Vivi Ann, Prasmickaite, Lina, Hill, Oliver, Sykora, Jaromir, Mælandsmo, Gunhild M, Engesæter, Birgit

“…In recent years, new treatment options for malignant melanoma patients have enhanced the overall survival for selected patients. Despite new hope, most…”
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Death domain-associated protein (DAXX) expression is associated with poor survival in metastatic high-grade serous carcinoma by Davidson, Ben, McFadden, Erin, Holth, Arild, Brunetti, Marta, Flørenes, Vivi Ann

“…The objective of this study was to analyze the expression and clinical role of mitosis regulators α-thalassemia/mental retardation syndrome X-linked (ATRX) and…”
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Wee1 is a novel independent prognostic marker of poor survival in post-chemotherapy ovarian carcinoma effusions by Slipicevic, Ana, Holth, Arild, Hellesylt, Ellen, Tropé, Claes G, Davidson, Ben, Flørenes, Vivi Ann

“…Abstract Objective Wee1-like kinase (Wee1) is a tyrosine kinase which negatively regulates entry into mitosis at the G2 to M-phase transition and has a role in…”
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