Search Results - "Fjeldsted, John C"

An Interlaboratory Evaluation of Drift Tube Ion Mobility–Mass Spectrometry Collision Cross Section Measurements by Stow, Sarah M, Causon, Tim J, Zheng, Xueyun, Kurulugama, Ruwan T, Mairinger, Teresa, May, Jody C, Rennie, Emma E, Baker, Erin S, Smith, Richard D, McLean, John A, Hann, Stephan, Fjeldsted, John C

“…Collision cross section (CCS) measurements resulting from ion mobility–mass spectrometry (IM-MS) experiments provide a promising orthogonal dimension of…”
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Recommendations for reporting ion mobility Mass Spectrometry measurements by Gabelica, Valérie, Shvartsburg, Alexandre A., Afonso, Carlos, Barran, Perdita, Benesch, Justin L.P., Bleiholder, Christian, Bowers, Michael T., Bilbao, Aivett, Bush, Matthew F., Campbell, J. Larry, Campuzano, Iain D.G., Causon, Tim, Clowers, Brian H., Creaser, Colin S., De Pauw, Edwin, Far, Johann, Fernandez‐Lima, Francisco, Fjeldsted, John C., Giles, Kevin, Groessl, Michael, Hogan, Christopher J., Hann, Stephan, Kim, Hugh I., Kurulugama, Ruwan T., May, Jody C., McLean, John A., Pagel, Kevin, Richardson, Keith, Ridgeway, Mark E., Rosu, Frédéric, Sobott, Frank, Thalassinos, Konstantinos, Valentine, Stephen J., Wyttenbach, Thomas

“…Here we present a guide to ion mobility mass spectrometry experiments, which covers both linear and nonlinear methods: what is measured, how the measurements…”
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Broadscale resolving power performance of a high precision uniform field ion mobility-mass spectrometer by May, Jody C, Dodds, James N, Kurulugama, Ruwan T, Stafford, George C, Fjeldsted, John C, McLean, John A

“…An extensive study of two current ion mobility resolving power theories ("conditional" and "semi-empirical") was undertaken using a recently developed drift…”
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Resolution of Isomeric Mixtures in Ion Mobility Using a Combined Demultiplexing and Peak Deconvolution Technique by May, Jody C, Knochenmuss, Richard, Fjeldsted, John C, McLean, John A

“…A combined data acquisition and data processing strategy for improving the sensitivity and resolution of ion mobility measurements is described. This strategy…”
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Separation of phosphorothioated oligonucleotide diastereomers using multiplexed drift tube ion mobility mass spectrometry by Demelenne, Alice, Nys, Gwenael, Nix, Cindy, Fjeldsted, John C., Crommen, Jacques, Fillet, Marianne

“…Hydrophilic interaction liquid chromatography (HILIC) coupled to drift tube ion mobility spectrometry (DTIMS) was used to separate diastereomers of five-unit…”
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Enhanced ion mobility resolution of Abeta isomers from human brain using high-resolution demultiplexing software by Mukherjee, Soumya, Fjeldsted, John C., Masters, Colin L., Roberts, Blaine R.

“…Isomerization of aspartic acid (Asp) residues in long-lived proteins is a key feature associated with neurodegenerative proteinopathies such as Alzheimer’s…”
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Conformational Ordering of Biomolecules in the Gas Phase: Nitrogen Collision Cross Sections Measured on a Prototype High Resolution Drift Tube Ion Mobility-Mass Spectrometer by May, Jody C, Goodwin, Cody R, Lareau, Nichole M, Leaptrot, Katrina L, Morris, Caleb B, Kurulugama, Ruwan T, Mordehai, Alex, Klein, Christian, Barry, William, Darland, Ed, Overney, Gregor, Imatani, Kenneth, Stafford, George C, Fjeldsted, John C, McLean, John A

“…Ion mobility-mass spectrometry measurements which describe the gas-phase scaling of molecular size and mass are of both fundamental and pragmatic utility…”
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Enhanced Collision Induced Unfolding and Electron Capture Dissociation of Native-like Protein Ions by Gadkari, Varun V, Ramírez, Carolina Rojas, Vallejo, Daniel D, Kurulugama, Ruwan T, Fjeldsted, John C, Ruotolo, Brandon T

“…Native ion mobility-mass spectrometry (IM-MS) is capable of revealing much that remains unknown within the structural proteome, promising such information on…”
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A Preprocessing Tool for Enhanced Ion Mobility–Mass Spectrometry-Based Omics Workflows by Bilbao, Aivett, Gibbons, Bryson C, Stow, Sarah M, Kyle, Jennifer E, Bloodsworth, Kent J, Payne, Samuel H, Smith, Richard D, Ibrahim, Yehia M, Baker, Erin S, Fjeldsted, John C

“…The ability to improve the data quality of ion mobility–mass spectrometry (IM-MS) measurements is of great importance for enabling modular and efficient…”
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A Modified Drift Tube Ion Mobility-Mass Spectrometer for Charge-Multiplexed Collision-Induced Unfolding by Vallejo, Daniel D, Polasky, Daniel A, Kurulugama, Ruwan T, Eschweiler, Joseph D, Fjeldsted, John C, Ruotolo, Brandon T

“…Collision-induced unfolding (CIU) of protein ions and their noncovalent complexes offers relatively rapid access to a rich portfolio of biophysical…”
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Collision-Induced Unfolding Reveals Stability Differences in Infliximab Therapeutics under Native and Heat Stress Conditions by Vallejo, Daniel D, Kang, Jukyung, Coghlan, Jill, Ramírez, Carolina Rojas, Polasky, Daniel A, Kurulugama, Ruwan T, Fjeldsted, John C, Schwendeman, Anna A, Ruotolo, Brandon T

“…Ion mobility-mass spectrometry (IM-MS) and collision-induced unfolding (CIU) assays of monoclonal antibody (mAb)-based biotherapeutics have proven sensitive to…”
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Effect of Sampling Rate and Data Pretreatment for Targeted and Nontargeted Analysis by Means of Liquid Chromatography Coupled to Drift Time Ion Mobility Quadruple Time-of-Flight Mass Spectrometry by Tötsch, Kristina, Fjeldsted, John C, Stow, Sarah M, Schmitz, Oliver J, Meckelmann, Sven W

“…Ion mobility as an additional separation dimension can help to resolve and annotate metabolite and lipid biomarkers and provides important information about…”
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Performance evaluation of in-source ion activation hardware for collision-induced unfolding of proteins and protein complexes on a drift tube ion mobility-mass spectrometer by Gadkari, Varun V, Juliano, Brock R, Mallis, Christopher S, May, Jody C, Kurulugama, Ruwan T, Fjeldsted, John C, McLean, John A, Russell, David H, Ruotolo, Brandon T

“…Native ion mobility-mass spectrometry (IM-MS) has emerged as an information-rich technique for gas phase protein structure characterization; however, IM…”
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Exploring Ion Mobility Mass Spectrometry Data File Conversions to Leverage Existing Tools and Enable New Workflows by Stow, Sarah M., Gibbons, Bryson C., Rorrer III, Leonard C., Royer, Lauren, Glaskin, Rebecca S., Slysz, Gordon W., Kurulugama, Ruwan T., Fjeldsted, John C., DeBord, Daniel, Bilbao, Aivett

“…Ion mobility (IM) is often combined with LC-MS experiments to provide an additional dimension of separation for complex sample analysis. While highly complex…”
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AutoCCS: automated collision cross-section calculation software for ion mobility spectrometry–mass spectrometry by Lee, Joon-Yong, Bilbao, Aivett, Conant, Christopher R, Bloodsworth, Kent J, Orton, Daniel J, Zhou, Mowei, Wilson, Jesse W, Zheng, Xueyun, Webb, Ian K, Li, Ailin, Hixson, Kim K, Fjeldsted, John C, Ibrahim, Yehia M, Payne, Samuel H, Jansson, Christer, Smith, Richard D, Metz, Thomas O

“…Abstract Motivation Ion mobility spectrometry (IMS) separations are increasingly used in conjunction with mass spectrometry (MS) for separation and…”
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Quasi‐continuous infrared matrix‐assisted laser desorption electrospray ionization source coupled to a quadrupole time‐of‐flight mass spectrometer for direct analysis from well plates by Arciniega, Cristina, Garrard, Kenneth P., Guymon, Jacob P., Manni, Jeffrey G., Apffel, Alex, Fjeldsted, John C., Muddiman, David C.

“…High‐throughput screening (HTS) is a technique mostly used by pharmaceutical companies to rapidly screen multiple libraries of compounds to find drug hits with…”
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Instrumental aspects of capillary supercritical fluid chromatography by Peaden, Paul A, Fjeldsted, John C, Lee, Milton L, Springston, Stephen R, Novotny, Milos

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Quasi-Continuous IR-MALDESI Source Coupled to a Q-TOF Mass Spectrometer for Direct Analysis from Well Plates by Arciniega, Cristina, Garrard, Kenneth P., Guymon, Jacob P., Manni, Jeffrey G., Apffel, Alex, Fjeldsted, John C., Muddiman, David C.

“…High-throughput screening (HTS) is a technique mostly used by pharmaceutical companies to rapidly screen multiple libraries of compounds to find drug hits with…”
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Capillary Supercritical Fluid Chromatography by Novotny, Milos, Springston, Stephen R, Peaden, Paul A, Fjeldsted, John C, Lee, Milton L

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AutoCCS: automated collision cross-section calculation software for ion mobility spectrometry–mass spectrometry by Lee, Joon-Yong, Bilbao, Aivett, Conant, Christopher R., Bloodsworth, Kent J., Orton, Daniel J., Zhou, Mowei, Wilson, Jesse W., Zheng, Xueyun, Webb, Ian K., Li, Ailin, Hixson, Kim K., Fjeldsted, John C., Ibrahim, Yehia M., Payne, Samuel H., Jansson, Christer, Smith, Richard D., Metz, Thomas O., Valencia, ed., Alfonso

“…Abstract Motivation Ion mobility spectrometry (IMS) separations are increasingly used in conjunction with mass spectrometry (MS) for separation and…”
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