Search Results - "Fivash, Matthew J."

Recombinant Origin of the Retrovirus XMRV by Paprotka, Tobias, Delviks-Frankenberry, Krista A., Cingöz, Oya, Martinez, Anthony, Kung, Hsing-Jien, Tepper, Clifford G., Hu, Wei-Shau, Fivash, Matthew J., Coffin, John M., Pathak, Vinay K.

“…The retrovirus XMRV (xenotropic murine leukemia virus—related virus) has been detected in human prostate tumors and in blood samples from patients with chronic…”
Get full text

Mutations in the connection domain of HIV-1 reverse transcriptase increase 3'-azido-3'-deoxythymidine resistance by Nikolenko, Galina N, Delviks-Frankenberry, Krista A, Palmer, Sarah, Maldarelli, Frank, Fivash, Matthew J. Jr, Coffin, John M, Pathak, Vinay K

“…We previously proposed that a balance between nucleotide excision and template RNA degradation plays an important role in nucleoside reverse transcriptase…”
Get full text

Functional Interplay Between Murine Leukemia Virus Glycogag, Serinc5, and Surface Glycoprotein Governs Virus Entry, with Opposite Effects on Gammaretroviral and Ebolavirus Glycoproteins by Ahi, Yadvinder S, Zhang, Shu, Thappeta, Yashna, Denman, Audrey, Feizpour, Amin, Gummuluru, Suryaram, Reinhard, Bjoern, Muriaux, Delphine, Fivash, Matthew J, Rein, Alan

“…Gammaretroviruses, such as murine leukemia viruses (MLVs), encode, in addition to the canonical Gag, Pol, and Env proteins that will form progeny virus…”
Get full text

DNA binding and 3'-end preferential activity of human tyrosyl-DNA phosphodiesterase by Dexheimer, Thomas S, Stephen, Andrew G, Fivash, Matthew J, Fisher, Robert J, Pommier, Yves

“…Human tyrosyl-DNA phosphodiesterase (Tdp1) processes 3'-blocking lesions, predominantly 3'-phosphotyrosyl bonds resulting from the trapping of topoisomerase I…”
Get full text

Gag-Dependent Enrichment of HIV-1 RNA near the Uropod Membrane of Polarized T Cells by Hatch, Steven C, Sardo, Luca, Chen, Jianbo, Burdick, Ryan, Gorelick, Robert, Fivash, Jr, Matthew J, Pathak, Vinay K, Hu, Wei-Shau

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Matrix-assisted laser desorption/ionization mass spectrometry reveals decreased calcylcin expression in small cell lung cancer by Lee, Hee Seok, Park, Jun Won, Chertov, Oleg, Colantonio, Simona, Simpson, John T., Fivash, Matthew J., Yoo, Chong Woo, Lee, Geon Kook, Zo, Jae Ill, Kim, Heung Tae, Kim, Hark Kyun

“…To date, most of the proteomic analyses on lung cancer tissue samples have been performed using surgical specimens, which are obtained after a diagnosis is…”
Get full text

Inhibition of prolidase activity by nickel causes decreased growth of proline auxotrophic CHO cells by Miltyk, Wojciech, Surazynski, Arkadiusz, Kasprzak, Kazimierz S., Fivash Jr, Matthew J., Buzard, Gregory S., Phang, James M.

“…Occupational exposure to nickel has been epidemiologically linked to increased cancer risk in the respiratory tract. Nickel‐induced cell transformation is…”
Get full text

Nucleic acid binding and chaperone properties of HIV-1 Gag and nucleocapsid proteins by Cruceanu, Margareta, Urbaneja, Maria A., Hixson, Catherine V., Johnson, Donald G., Datta, Siddhartha A., Fivash, Matthew J., Stephen, Andrew G., Fisher, Robert J., Gorelick, Robert J., Casas-Finet, Jose R., Rein, Alan, Rouzina, Ioulia, Williams, Mark C.

“…The Gag polyprotein of HIV-1 is essential for retroviral replication and packaging. The nucleocapsid (NC) protein is the primary region for the interaction of…”
Get full text

In Vitro Inhibition of the Enzymatic Activity of Tumor Suppressor FHIT Gene Product by Carcinogenic Transition Metals by Kowara, Renata, Karaczyn, Aldona A, Fivash, Matthew J, Kasprzak, Kazimierz S

“…FHIT (Fragile Histidine Triad) is a human tumor suppressor gene. The Fhit protein is believed to inhibit tumor growth by inducing apoptosis through interaction…”
Get full text

Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides by Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., Smith, Lindsey R., Worthy, Karen M., Simpson, John T., Shoemaker, Robert, McNitt, Karen L., Johnson, Donald G., Hixson, Catherine V., Gorelick, Robert J., Fabris, Daniele, Henderson, Louis E., Rein, Alan

“…The HIV-1 nucleocapsid (NC) protein is a small, basic protein containing two retroviral zinc fingers. It is a highly active nucleic acid chaperone; because of…”
Get full text

Identification of Shc Src Homology 2 Domain-Binding Peptoid−Peptide Hybrids by Choi, Won Jun, Kim, Sung-Eun, Stephen, Andrew G, Weidlich, Iwona, Giubellino, Alessio, Liu, Fa, Worthy, Karen M, Bindu, Lakshman, Fivash, Matthew J, Nicklaus, Marc C, Bottaro, Donald P, Fisher, Robert J, Burke, Terrence R

“…A fluorescence anisotropy (FA) competition-based Shc Src homology 2 (SH2) domain-binding was established using the high affinity fluorescein isothiocyanate…”
Get full text

Elucidation of New Binding Interactions with the Human Tsg101 Protein Using Modified HIV-1 Gag-p6 Derived Peptide Ligands by Kim, Sung-Eun, Liu, Fa, Im, Young Jun, Stephen, Andrew G, Fivash, Matthew J, Waheed, Abdul A, Freed, Eric O, Fisher, Robert J, Hurley, James H, Burke, Terrence R

“…Targeting protein−protein interactions is gaining greater recognition as an attractive approach to therapeutic development. An example of this may be found…”
Get full text

A novel macrocyclic tetrapeptide mimetic that exhibits low-picomolar Grb2 SH2 domain-binding affinity by Shi, Zhen-Dan, Lee, Kyeong, Liu, Hongpeng, Zhang, Manchao, Roberts, Lindsey R, Worthy, Karen M, Fivash, Matthew J, Fisher, Robert J, Yang, Dajun, Burke, Terrence R

“…The growth factor receptor-bound protein 2 (Grb2) is an SH2 domain-containing docking module that participates in the signaling of numerous oncogenic growth…”
Get full text

A high-throughput screen for identification of molecular mimics of Smac/DIABLO utilizing a fluorescence polarization assay by Glover, Constance J., Hite, Karen, DeLosh, Renee, Scudiero, Dominic A., Fivash, Matthew J., Smith, Lindsey R., Fisher, Robert J., Wu, Jia-Wei, Shi, Yigong, Kipp, Rachael A., McLendon, George L., Sausville, Edward A., Shoemaker, Robert H.

“…Resistance to apoptosis is afforded by inhibitor of apoptosis proteins (IAPs) which bind to and inhibit the caspases responsible for cleavage of substrates…”
Get full text

Measuring the binding stoichiometry of HIV-1 Gag to very-low-density oligonucleotide surfaces using surface plasmon resonance spectroscopy by Stephen, Andrew G, Datta, Siddhartha A K, Worthy, Karen M, Bindu, Lakshman, Fivash, Matthew J, Turner, Kevin B, Fabris, Daniele, Rein, Alan, Fisher, Robert J

“…The interaction of the HIV Gag polyprotein with nucleic acid is a critical step in the assembly of viral particles. The Gag polyprotein is composed of the…”
Get full text

Identification and characterization of peptides that bind to cyanovirin-N, a potent human immunodeficiency virus-inactivating protein by Han, Zhaozhong, Simpson, John T, Fivash, Matthew J, Fisher, Robert, Mori, Toshiyuki

“…Cyanovirin-N (CV-N) exerts a potent human immunodeficiency virus (HIV)-inactivating activity against diverse strains of HIV by binding to the viral surface…”
Get full text

Complex interactions of HIV-1 nucleocapsid protein with oligonucleotides by Fisher, Robert J., Fivash, Matthew J., Stephen, Andrew G., Hagan, Nathan A., Shenoy, Shilpa R., Medaglia, Maxine V., Smith, Lindsey R., Worthy, Karen M., Simpson, John T., Shoemaker, Robert, McNitt, Karen L., Johnson, Donald G., Hixson, Catherine V., Gorelick, Robert J., Fabris, Daniele, Henderson, Louis E., Rein, Alan

“…The HIV-1 nucleocapsid (NC) protein is a small, basic protein containing two retroviral zinc fingers. It is a highly active nucleic acid chaperone; because of…”
Get full text

Mechanistic Studies of the Inhibition of MutT dGTPase by the Carcinogenic Metal Ni(II) by Porter, Dale W, Nelson, Victor C, Fivash, Matthew J, Kasprzak, Kazimierz S

“…Promutagenic 8-oxo-7,8-dihydro-2‘-deoxyguanosine (8-oxo-dG) levels are increased in DNA of animals exposed to carcinogenic metals, such as Ni(II). Besides…”
Get full text

Functional Interplay Between Murine Leukemia Virus Glycogag, Serinc5, and Surface Glycoprotein Governs Virus Entry, with Opposite Effects on Gammaretroviral and Ebolavirus Glycoproteins by Ahi, Yadvinder S., Zhang, Shu, Thappeta, Yashna, Denman, Audrey, Feizpour, Amin, Gummuluru, Suryaram, Reinhard, Bjoern, Muriaux, Delphine, Fivash, Matthew J., Rein, Alan

“…Gammaretroviruses, such as murine leukemia viruses (MLVs), encode, in addition to the canonical Gag, Pol, and Env proteins that will form progeny virus…”
Get full text

Identificaiton of Shc Src Homology 2 Domain-Binding Peptoid – Peptide Hybrids by Choi, Won Jun, Kim, Sung Eun, Stephen, Andrew G., Weidlich, Iwona, Giubellino, Alessio, Liu, Fa, Worthy, Karen M., Bindu, Lakshman, Fivash, Matthew J., Nicklaus, Marc C., Bottaro, Donald P., Fisher, Robert J., Burke, Terrence R.

“…A fluorescence anisotropy (FA) competition – based Shc Src homology 2 (SH2) domain-binding was established using the high affinity fluorescein isothiocyanate…”
Get full text