Search Results - "Fitzpatrick, P.F"

Site-directed mutagenesis of serine 40 of rat tyrosine hydroxylase. Effects of dopamine and cAMP-dependent phosphorylation on enzyme activity by DAUBNER, S. C, LAURIANO, C, HAYCOCK, J. W, FITZPATRICK, P. F

“…Rat tyrosine hydroxylase expressed with a baculovirus expression system contains covalent phosphate and has kinetic parameters consistent with those expected…”
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Purification and Characterization of the Flavoprotein Tryptophan 2-Monooxygenase Expressed at High Levels in Escherichia coli by Emanuele, J.J., Heasley, C.J., Fitzpatrick, P.F.

“…Tryptophan 2-monooxygenase from Pseudomonas savastanoi is a flavoprotein which catalyzes the formation of indoleacetamide from tryptophan. This is the first…”
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A tryptophan-2-monooxygenase based amperometric biosensor for L-tryptophan determination: use of a competitive inhibitor as a tool for selectivity increase by Simonian, A.L, Rainina, E.I, Fitzpatrick, P.F, Wild, J.R

“…A new flow-injection amperometric biosensor based on immobilized tryptophan-2-monooxygenase (TMO) has been developed for reagentless L-tryptophan…”
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pH and kinetic isotope effects on the oxidative half-reaction of D-amino-acid oxidase by DENU, J. M, FITZPATRICK, P. F

“…D-Amino-acid oxidase catalyzes the oxidation of D-amino acids to imino acids. In the oxidative half-reaction, oxygen reacts with the reduced enzyme-imino acid…”
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On the Catalytic Mechanism of Tryptophan Hydroxylase by Moran, Graham R, Derecskei-Kovacs, Agnes, Hillas, Patrick J, Fitzpatrick, Paul F

“…Tryptophan hydroxylase catalyzes the hydroxylation of tryptophan using tetrahydrobiopterin and molecular oxygen. With tyrosine as a substrate, the amount of…”
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Biochemical and Physical Characterization of the Active FAD-Containing Form of Nitroalkane Oxidase from Fusarium oxysporum by Gadda, Giovanni, Fitzpatrick, Paul F

“…Nitroalkane oxidase from Fusarium oxysporum catalyzes the oxidation of nitroalkanes to aldehydes with production of nitrite and hydrogen peroxide. The enzyme…”
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Identification of the Naturally Occurring Flavin of Nitroalkane Oxidase from Fusarium oxysporum as a 5-Nitrobutyl-FAD and Conversion of the Enzyme to the Active FAD-containing Form by Gadda, Giovanni, Edmondson, Ricky D., Russell, David H., Fitzpatrick, Paul F.

“…Nitroalkane oxidase from Fusarium oxysporum catalyzes the oxidation of nitroalkanes to aldehydes with production of nitrite and hydrogen peroxide. The…”
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Identification of the intersubunit binding region in rat tyrosine hydroxylase by Lohse, D L, Fitzpatrick, P F

“…Limited proteolysis converts the 39200 molecular weight catalytic domain of rat tyrosine hydroxylase to a monomer with a molecular weight of 37600. The…”
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Substituted Alcohols as Mechanistic Probes of Alcohol Oxidase by Menon, V., Hsieh, C.T., Fitzpatrick, P.F.

“…The flavoprotein alcohol oxidase catalyzes the oxidation of primary and secondary alcohols to aldehydes, transferring the electrons to oxygen to form hydrogen…”
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Lysine241 of tyrosine hydroxylase is not required for binding of tetrahydrobiopterin substrate by Daubner, S C, Fitzpatrick, P F

“…The lysine residues at positions 194 and 198 in phenylalanine hydroxylase have been shown to react with a photoaffinity label which is an analog of…”
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Thiazolidine-2-carboxylic acid, an adduct of cysteamine and glyoxylate, as a substrate for D-amino acid oxidase by Fitzpatrick, P F, Massey, V

“…A mixture of cysteamine and glyoxylate, proposed by Hamilton et al. to form the physiological substrate of hog kidney D-amino acid oxidase (Hamilton, G. A.,…”
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3-Phenylpropenes as mechanism-based inhibitors of dopamine .beta.-hydroxylase: evidence for a radical mechanism by Fitzpatrick, Paul F, Flory, Donald R, Villafranca, Joseph J

“…A series of ring-substituted 3-phenylpropenes has been examined as mechanism-based inhibitors for the copper protein dopamine beta-hydroxylase. p-HO-, p-CH3O-,…”
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Identification of the rate-limiting step in serine proteinases from the effect of temperature on steady-state kinetics by Fitzpatrick, P F

“…The effect of temperature on the steady-state kinetics of porcine pancreatic elastase can be used to determine whether acylation or deacylation is the…”
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2-thioflavins as active site probes of flavoproteins by CLAIBORNE, A, MASSEY, V, FITZPATRICK, P. F, SCHOPFER, L. M

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