Search Results - "Fitzmaurice, Timothy J"
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Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection
Published in PLoS pathogens (01-06-2017)“…The innate immune system is a critical component of host defence against microbial pathogens, but effective responses require an ability to distinguish between…”
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Dendritic Cell-Derived TSLP Negatively Regulates HIF-1α and IL-1β During Dectin-1 Signaling
Published in Frontiers in immunology (08-05-2019)“…Thymic stromal lymphopoietin (TSLP) is a functionally pleotropic cytokine important in immune regulation, and TSLP dysregulation is associated with numerous…”
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Genetic imprint of vaccination on simian/human immunodeficiency virus type 1 transmitted viral genomes in rhesus macaques
Published in PloS one (14-08-2013)“…Understanding the genetic, antigenic and structural changes that occur during HIV-1 infection in response to pre-existing immunity will facilitate current…”
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IRE1α mediates PKR activation in response to Chlamydia trachomatis infection
Published in Microbes and infection (01-07-2016)“…Protein kinase RNA activated (PKR) is a crucial mediator of anti-viral responses but is reported to be activated by multiple non-viral stimuli. However,…”
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Genetic Imprint of Vaccination on Simian/Human Immunodeficiency Virus Type 1 Transmitted Viral Genomes in Rhesus Macaques. e70814
Published in PloS one (01-08-2013)“…Understanding the genetic, antigenic and structural changes that occur during HIV-1 infection in response to pre-existing immunity will facilitate current…”
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Journal Article