Search Results - "Fitzgerald‐Bocarsly, Patricia"

Senescence‐associated β‐galactosidase reveals the abundance of senescent CD8+ T cells in aging humans by Martínez‐Zamudio, Ricardo I., Dewald, Hannah K., Vasilopoulos, Themistoklis, Gittens‐Williams, Lisa, Fitzgerald‐Bocarsly, Patricia, Herbig, Utz

“…Aging leads to a progressive functional decline of the immune system, rendering the elderly increasingly susceptible to disease and infection. The degree to…”
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Plasmacytoid dendritic cells in HIV infection: striking a delicate balance by Fitzgerald-Bocarsly, Patricia, Jacobs, Evan S

“…Review of the plasmacytoid dendritic cells and their potential for beneficial or detrimental roles in HIV‐1 infection. pDC are the most potent IFN‐α‐producing…”
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Modulation of human β-defensin-1 (hBD-1) in plasmacytoid dendritic cells (PDC), monocytes, and epithelial cells by influenza virus, Herpes simplex virus, and Sendai virus and its possible role in innate immunity by Ryan, Lisa K., Dai, Jihong, Yin, Zhiwei, Megjugorac, Nicholas, Uhlhorn, Victoria, Yim, Sunghan, Schwartz, Kyell D., Abrahams, Joshua M., Diamond, Gill, Fitzgerald‐Bocarsly, Patricia

“…Early in infection, influenza, HSV‐1 and Sendai virus modulate hBD‐1 in human plasmacytoid dendritic cells, monocytes and epithelial cells, suggesting…”
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Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons by Stone, Rivka C., Feng, Di, Deng, Jing, Singh, Sukhwinder, Yang, Lisong, Fitzgerald-Bocarsly, Patricia, Eloranta, Maija-Leena, Rönnblom, Lars, Barnes, Betsy J.

“…Objective Genetic variants of interferon regulatory factor 5 (IRF‐5) are associated with susceptibility to systemic lupus erythematosus (SLE). IRF‐5 regulates…”
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Comparative analysis of IRF and IFN-alpha expression in human plasmacytoid and monocyte-derived dendritic cells by Izaguirre, Alexander, Barnes, Betsy J., Amrute, Sheela, Yeow, Wen‐Shuz, Megjugorac, Nicholas, Dai, Jihong, Feng, Di, Chung, Eugene, Pitha, Paula M., Fitzgerald‐Bocarsly, Patricia

“…Plasmacytoid dendritic cells (PDC) produce high levels of type I IFN upon stimulation with viruses, while monocytes and monocyte‐derived dendritic cells (MDDC)…”
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Virally stimulated plasmacytoid dendritic cells produce chemokines and induce migration of T and NK cells by Megjugorac, Nicholas J., Young, Howard A., Amrute, Sheela B., Olshalsky, Stacey L., Fitzgerald‐Bocarsly, Patricia

“…The natural interferon (IFN)‐producing cell is now known to be identical to the plasmacytoid dendritic cell (PDC). These are Lin−, CD123+, CD11c−, and human…”
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The Nature of the Principal Type 1 Interferon-Producing Cells in Human Blood by Siegal, Frederick P., Kadowaki, Norimitsu, Shodell, Michael, Fitzgerald-Bocarsly, Patricia A., Shah, Kokila, Ho, Stephen, Antonenko, Svetlana, Liu, Yong-Jun

“…Interferons (IFNs) are the most important cytokines in antiviral immune responses. "Natural IFN-producing cells" (IPCs) in human blood express CD4 and major…”
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Triggering of the cGAS-STING Pathway in Human Plasmacytoid Dendritic Cells Inhibits TLR9-Mediated IFN Production by Deb, Pratik, Dai, Jihong, Singh, Sukhwinder, Kalyoussef, Evelyne, Fitzgerald-Bocarsly, Patricia

“…Plasmacytoid dendritic cells (pDCs) are potent producers of type I and type III IFNs and play a major role in antiviral immunity and autoimmune disorders. The…”
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Antifungal Activity of Plasmacytoid Dendritic Cells and the Impact of Chronic HIV Infection by Maldonado, Samuel, Fitzgerald-Bocarsly, Patricia

“…Due to the effectiveness of combined antiretroviral therapy, people living with HIV can control viral replication and live longer lifespans than ever. However,…”
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Frontline Science: AMPK regulates metabolic reprogramming necessary for interferon production in human plasmacytoid dendritic cells by Hurley, Harry J., Dewald, Hannah, Rothkopf, Zachary S., Singh, Sukhwinder, Jenkins, Frank, Deb, Pratik, De, Saurav, Barnes, Betsy J., Fitzgerald‐Bocarsly, Patricia

“…Plasmacytoid dendritic cells (pDCs) play a crucial role in innate viral immunity as the most potent producers of type I interferons (IFN) in the human body…”
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Type III IFNs are produced by and stimulate human plasmacytoid dendritic cells by Yin, Zhiwei, Dai, Jihong, Deng, Jing, Sheikh, Faruk, Natalia, Mahwish, Shih, Tiffany, Lewis-Antes, Anita, Amrute, Sheela B, Garrigues, Ursula, Doyle, Sean, Donnelly, Raymond P, Kotenko, Sergei V, Fitzgerald-Bocarsly, Patricia

“…Plasmacytoid dendritic cells (pDC) are rare cells found in peripheral blood and lymphoid tissues. pDC are considered to be "professional" type I IFN-producing…”
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Glycomic alterations in HIV infection: one galactose or two? by Hurley, Harry J., Dewald, Hannah K., Fitzgerald‐Bocarsly, Patricia

“…Discussion on the role of the IgG glycome in immunity and the contribution of HIV to antibody glycosylation…”
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Insulin-like growth factor I regulates G2/M progression through mammalian target of rapamycin signaling in oligodendrocyte progenitors by Min, Jungsoo, Singh, Sukhwinder, Fitzgerald-Bocarsly, Patricia, Wood, Teresa L.

“…Extrinsic factors including growth factors influence decisions of oligodendrocyte progenitor cells (OPCs) to continue cell cycle progression or exit the cell…”
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Elevated plasma p-tau231 is associated with reduced generalization and medial temporal lobe dynamic network flexibility among healthy older African Americans by Budak, Miray, Fausto, Bernadette A., Osiecka, Zuzanna, Sheikh, Mustafa, Perna, Robert, Ashton, Nicholas, Blennow, Kaj, Zetterberg, Henrik, Fitzgerald-Bocarsly, Patricia, Gluck, Mark A.

“…Background Phosphorylated tau (p-tau) and amyloid beta (A[beta]) in human plasma may provide an affordable and minimally invasive method to evaluate…”
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Editorial: IFN‐β immunomodulation: a tail of two STATS by Rohowsky‐Kochan, Christine, Fitzgerald‐Bocarsly, Patricia

“…Discussion of how IFNβ modulates immune responses mediated through STATs‐1 and ‐2…”
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Regulation of Transcription Factor E2-2 in Human Plasmacytoid Dendritic Cells by Monocyte-Derived TNFα by Dewald, Hannah K, Hurley, Harry J, Fitzgerald-Bocarsly, Patricia

“…Plasmacytoid dendritic cells (pDCs) are innate immune cells and potent producers of interferon alpha (IFNα). Regulation of pDCs is crucial for prevention of…”
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Dcp2 Decapping Protein Modulates mRNA Stability of the Critical Interferon Regulatory Factor (IRF) IRF-7 by Li, You, Dai, Jihong, Song, Mangen, Fitzgerald-Bocarsly, Patricia, Kiledjian, Megerditch

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Interferon regulatory factor 7-mediated responses are defective in cord blood plasmacytoid dendritic cells by Danis, Bénédicte, George, Thaddeus C, Goriely, Stanislas, Dutta, Binita, Renneson, Joëlle, Gatto, Laurent, Fitzgerald-Bocarsly, Patricia, Marchant, Arnaud, Goldman, Michel, Willems, Fabienne, De Wit, Dominique

“…Plasmacytoid dendritic cells (pDC) are specialized in massive production of type I interferons (IFN) upon viral infections. Activation of IFN regulatory factor…”
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Natural interferon-alpha producing cells: the plasmacytoid dendritic cells by Fitzgerald-Bocarsly, Patricia

“…NIPCs have had a long history of study, with the first observations of peripheral blood cells with IFN-producing capacity being made approximately 20 years…”
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Two Discrete Promoters Regulate the Alternatively Spliced Human Interferon Regulatory Factor-5 Isoforms by Mancl, Margo E., Hu, Guodong, Sangster-Guity, Niquiche, Olshalsky, Stacey L., Hoops, Katherine, Fitzgerald-Bocarsly, Patricia, Pitha, Paula M., Pinder, Karen, Barnes, Betsy J.

“…Interferon regulatory factor-5 (IRF-5) is a mediator of virus-induced immune activation and type I interferon (Ifn) gene regulation. In human primary…”
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