Search Results - "Fitzgerald, Kathleen"

Creating an Ideal World: A Review of Work, Love, and Learning in Utopia: Equality Reimagined by Fitzgerald, Kathleen J.

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Life in 3D is never flat: 3D models to optimise drug delivery by Fitzgerald, Kathleen A., Malhotra, Meenakshi, Curtin, Caroline M., O' Brien, Fergal J., O' Driscoll, Caitriona M.

“…The development of safe, effective and patient-acceptable drug products is an expensive and lengthy process and the risk of failure at different stages of the…”
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A cognitively enhanced online Tai Ji Quan training intervention for community-dwelling older adults with mild cognitive impairment: A feasibility trial by Li, Fuzhong, Harmer, Peter, Fitzgerald, Kathleen, Winters-Stone, Kerri

“…This study examines the feasibility, acceptability, and safety of a newly developed cognitive-enhancing Tai Ji Quan training intervention, delivered via remote…”
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Implementing an Evidence-Based Fall Prevention Intervention in Community Senior Centers by Li, Fuzhong, Harmer, Peter, Fitzgerald, Kathleen

“…To evaluate the impact of implementing an evidence-based fall prevention intervention in community senior centers. We used a single-group design to evaluate…”
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Risk factors associated with the development of osteoradionecrosis (ORN) in Head and Neck cancer patients in Ireland: A 10-year retrospective review by Fitzgerald, Kathleen T., Lyons, Ciara, England, Andrew, McEntee, Mark F., Devine, Annemarie, O'Donovan, Theresa, O'Sullivan, Eleanor

“…•Low ORN incidence 4.4% (47/1,050)•Increased risk ORN with mandibular surgery.•Complete ORN resolution in 17% of patients.•Opportunities for risk reduction…”
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Response to letter to the editor by Somay et al., re: “Risk factors associated with the development of osteoradionecrosis (ORN) in head and neck cancer patients in Ireland: A 10-year retrospective review” by Fitzgerald, Kathleen T., Lyons, Ciara, England, Andrew, McEntee, Mark F., Devine, Annemarie, O’Donovan, Theresa, O’Sullivan, Eleanor

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More than $1 billion needed annually to secure Africa’s protected areas with lions by Lindsey, Peter A., Miller, Jennifer R. B., Petracca, Lisanne S., Coad, Lauren, Dickman, Amy J., Fitzgerald, Kathleen H., Flyman, Michael V., Funston, Paul J., Henschel, Philipp, Kasiki, Samuel, Knights, Kathryn, Loveridge, Andrew J., Macdonald, David W., Mandisodza-Chikerema, Roseline L., Nazerali, Sean, Plumptre, Andrew J., Stevens, Riko, Van Zyl, Hugo W., Hunter, Luke T. B.

“…Protected areas (PAs) play an important role in conserving biodiversity and providing ecosystem services, yet their effectiveness is undermined by funding…”
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The use of collagen-based scaffolds to simulate prostate cancer bone metastases with potential for evaluating delivery of nanoparticulate gene therapeutics by Fitzgerald, Kathleen A, Guo, Jianfeng, Tierney, Erica G, Curtin, Caroline M, Malhotra, Meenakshi, Darcy, Raphael, O'Brien, Fergal J, O'Driscoll, Caitriona M

“…Abstract Prostate cancer bone metastases are a leading cause of cancer-related death in men with current treatments offering only marginally improved rates of…”
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Prolyl hydroxylase-1 negatively regulates IκB kinase-β, giving insight into hypoxia-induced NFκB activity by Cummins, Eoin P., Berra, Edurne, Comerford, Katrina M., Ginouves, Amandine, Fitzgerald, Kathleen T., Seeballuck, Fergal, Godson, Catherine, Nielsen, Jens E., Moynagh, Paul, Pouyssegur, Jacques, Taylor, Cormac T.

“…Hypoxia is a feature of the microenvironment of a growing tumor. The transcription factor NFκB is activated in hypoxia, an event that has significant…”
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Seating and Wheeled Mobility Clinicians Contribute to the Wound Care Team by Carver, Cathy H., Mullis, Stacey, Fitzgerald, Kathleen H.

“…Many know that the wound care team consists of physicians and nurses with specialized training. Many may not know of physical therapists (PT) or occupational…”
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A novel, anisamide-targeted cyclodextrin nanoformulation for siRNA delivery to prostate cancer cells expressing the sigma-1 receptor by Fitzgerald, Kathleen A., Malhotra, Meenakshi, Gooding, Matt, Sallas, Florence, Evans, James C., Darcy, Raphael, O’Driscoll, Caitriona M.

“…[Display omitted] Prostate cancer is a leading cause of cancer-related death in men and RNA interference (RNAi) has emerged as a potential therapeutic option…”
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Conserving Africa’s wildlife and wildlands through the COVID-19 crisis and beyond by Lindsey, Peter, Allan, James, Brehony, Peadar, Dickman, Amy, Robson, Ashley, Begg, Colleen, Bhammar, Hasita, Blanken, Lisa, Breuer, Thomas, Fitzgerald, Kathleen, Flyman, Michael, Gandiwa, Patience, Giva, Nicia, Kaelo, Dickson, Nampindo, Simon, Nyambe, Nyambe, Steiner, Kurt, Parker, Andrew, Roe, Dilys, Thomson, Paul, Trimble, Morgan, Caron, Alexandre, Tyrrell, Peter

“…The SARS-CoV-2 virus and COVID-19 illness are driving a global crisis. Governments have responded by restricting human movement, which has reduced economic…”
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Motivational Interviewing: Improving Confidence With Self-care Management in Postoperative Thoracolumbar Spine Patients by Scheffel, Kimberly, Amidei, Christina, Fitzgerald, Kathleen A

“…Patients undergoing thoracic or lumbar spine surgery often lack confidence with self-care management of symptoms contributing to disability, such as pain, lack…”
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The influence of size and charge of chitosan/polyglutamic acid hollow spheres on cellular internalization, viability and blood compatibility by Dash, Biraja C, Réthoré, Gildas, Monaghan, Michael, Fitzgerald, Kathleen, Gallagher, William, Pandit, Abhay

“…Abstract Polymeric hollow spheres can be tailored as efficient carriers of various therapeutic molecules due to their tunable properties. However, the entry of…”
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Formulation and Evaluation of Anisamide-Targeted Amphiphilic Cyclodextrin Nanoparticles To Promote Therapeutic Gene Silencing in a 3D Prostate Cancer Bone Metastases Model by Evans, James C, Malhotra, Meenakshi, Fitzgerald, Kathleen A, Guo, Jianfeng, Cronin, Michael F, Curtin, Caroline M, O’Brien, Fergal J, Darcy, Raphael, O’Driscoll, Caitriona M

“…In recent years, RNA interference (RNAi) has emerged as a potential therapeutic offering the opportunity to treat a wide range of diseases, including prostate…”
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Nanoparticle-mediated siRNA delivery assessed in a 3D co-culture model simulating prostate cancer bone metastasis by Fitzgerald, Kathleen A., Guo, Jianfeng, Raftery, Rosanne M., Castaño, Irene Mencía, Curtin, Caroline M., Gooding, Matt, Darcy, Raphael, O’ Brien, Fergal J., O’ Driscoll, Caitriona M.

“…[Display omitted] siRNA has emerged as a potential therapeutic for the treatment of prostate cancer but effective delivery remains a major barrier to its…”
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Biomimetic gold nanocomplexes for gene knockdown： Will gold deliver dividends for small interfering RNA nanomedicines by Guo, Jianfeng, Rahme, Kamil, Fitzgerald, Kathleen A., Holmes, Justin D., O’Driscoll, Caitriona M.

“…RNA interference （RNAi） effectors such as small interfering RNA （siRNA） and micro RNA （miRNA） can selectively downregulate any gene implicated in the pathology…”
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Examination of cell–host–biomaterial interactions via high-throughput technologies: A re-appraisal by Power, Karen A, Fitzgerald, Kathleen T, Gallagher, William M

“…Abstract Biomaterials are required to act harmoniously when exposed to the body or bodily fluids. Investigating cellular or in vivo phenotypic responses and…”
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The role of transcription factors in prostate cancer and potential for future RNA interference therapy by Fitzgerald, Kathleen A, Evans, James C, McCarthy, Joanna, Guo, Jianfeng, Prencipe, Maria, Kearney, Meghan, Watson, William R, O'Driscoll, Caitriona M

“…Prostate cancer is a leading cause of cancer-related death in men and current treatments offer only a modest survival benefit in advanced stages of the…”
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The mechanism of internalization of glycosylphosphatidylinositol-anchored prion protein by Sunyach, Claire, Jen, Angela, Deng, Juelin, Fitzgerald, Kathleen T., Frobert, Yveline, Grassi, Jacques, McCaffrey, Mary W., Morris, Roger

“…The mode of internalization of glycosylphosphatidylinositol‐anchored proteins, lacking any cytoplasmic domain by which to engage adaptors to recruit them into…”
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