Search Results - "Fitzgerald, J Ross"
-
1
Livestock-associated Staphylococcus aureus : origin, evolution and public health threat
Published in Trends in microbiology (Regular ed.) (01-04-2012)“…Staphylococcus aureus is a major pathogen responsible for severe nosocomial and community-associated infections of humans and infections of economically…”
Get full text
Journal Article -
2
Population genomics of bacterial host adaptation
Published in Nature reviews. Genetics (01-09-2018)“…Some bacteria can transfer to new host species, and this poses a risk to human health. Indeed, an estimated 60% of all human pathogens have originated from…”
Get full text
Journal Article -
3
Mechanisms of host adaptation by bacterial pathogens
Published in FEMS microbiology reviews (20-06-2024)“…Abstract The emergence of new infectious diseases poses a major threat to humans, animals, and broader ecosystems. Defining factors that govern the ability of…”
Get full text
Journal Article -
4
Genome hypermobility by lateral transduction
Published in Science (American Association for the Advancement of Science) (12-10-2018)“…Genetic transduction is a major evolutionary force that underlies bacterial adaptation. Here we report that the temperate bacteriophages of engage in a…”
Get full text
Journal Article -
5
Staphylococcus aureus in Animals
Published in Microbiology spectrum (01-05-2019)“…is a mammalian commensal and opportunistic pathogen that colonizes niches such as skin, nares and diverse mucosal membranes of about 20-30% of the human…”
Get full text
Journal Article -
6
Host-specialized fibrinogen-binding by a bacterial surface protein promotes biofilm formation and innate immune evasion
Published in PLoS pathogens (19-06-2019)“…Fibrinogen is an essential part of the blood coagulation cascade and a major component of the extracellular matrix in mammals. The interface between fibrinogen…”
Get full text
Journal Article -
7
RNase III CLASH in MRSA uncovers sRNA regulatory networks coupling metabolism to toxin expression
Published in Nature communications (22-06-2022)“…Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterial pathogen responsible for significant human morbidity and mortality. Post-transcriptional…”
Get full text
Journal Article -
8
Staphylococcus intermedius group of bacterial pathogens: species re-classification, pathogenesis and the emergence of meticillin resistance
Published in Veterinary dermatology (01-10-2009)“…Staphylococcus intermedius has been long regarded as the common cause of pyoderma in dogs and other animals. Despite its clinical importance, our understanding…”
Get full text
Journal Article -
9
The interaction of bacterial pathogens with platelets
Published in Nature reviews. Microbiology (01-06-2006)“…In recent years, the frequency of serious cardiovascular infections such as endocarditis has increased, particularly in association with nosocomially acquired…”
Get full text
Journal Article -
10
Bacteriophage-driven emergence and expansion of Staphylococcus aureus in rodent populations
Published in PLoS pathogens (01-07-2024)“…Human activities such as agriculturalization and domestication have led to the emergence of many new pathogens via host-switching events between humans,…”
Get full text
Journal Article -
11
The role of ‘filth flies’ in the spread of antimicrobial resistance
Published in Travel medicine and infectious disease (01-03-2018)“…‘Filth flies’ feed and develop in excrement and decaying matter and can transmit enteric pathogens to humans and animals, leading to colonization and…”
Get full text
Journal Article -
12
Diversity and pathogenesis of Staphylococcus aureus from bovine mastitis: current understanding and future perspectives
Published in BMC veterinary research (24-03-2022)“…Staphylococcus aureus is a leading cause of bovine mastitis worldwide. Despite some improved understanding of disease pathogenesis, progress towards new…”
Get full text
Journal Article -
13
Livestock origin for a human pandemic clone of community-associated methicillin-resistant Staphylococcus aureus
Published in mBio (13-08-2013)“…The importance of livestock as a source of bacterial pathogens with the potential for epidemic spread in human populations is unclear. In recent years, there…”
Get full text
Journal Article -
14
Radical genome remodelling accompanied the emergence of a novel host-restricted bacterial pathogen
Published in PLoS pathogens (01-05-2021)“…The emergence of new pathogens is a major threat to public and veterinary health. Changes in bacterial habitat such as a switch in host or disease tropism are…”
Get full text
Journal Article -
15
A single natural nucleotide mutation alters bacterial pathogen host tropism
Published in Nature genetics (01-04-2015)“…José Penadés and colleagues examine host adaptation and specificity for Staphylococcus aureus with analysis of the whole-genome sequences of strains isolated…”
Get full text
Journal Article -
16
Molecular Diagnostic Identification of Staphylococcus pseudintermedius
Published in Journal of Clinical Microbiology (01-02-2009)“…We report the first diagnostic test for the identification of Staphylococcus pseudintermedius involving a simple PCR-restriction fragment length polymorphism…”
Get full text
Journal Article -
17
Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing
Published in Nature communications (09-12-2021)“…Legionella pneumophila is the most common cause of the severe respiratory infection known as Legionnaires’ disease. However, the microorganism is typically a…”
Get full text
Journal Article -
18
The Role of Gram-Positive Surface Proteins in Bacterial Niche- and Host-Specialization
Published in Frontiers in microbiology (29-10-2020)“…Gram-positive bacterial pathogens have an array of proteins on their cell surface that mediate interactions with the host environment. In particular, bacterial…”
Get full text
Journal Article -
19
Recent human-to-poultry host jump, adaptation, and pandemic spread of Staphylococcus aureus
Published in Proceedings of the National Academy of Sciences - PNAS (17-11-2009)“…The impact of globalization on the emergence and spread of pathogens is an important veterinary and public health issue. Staphylococcus aureus is a notorious…”
Get full text
Journal Article -
20
A graph-based approach for the visualisation and analysis of bacterial pangenomes
Published in BMC bioinformatics (08-10-2022)“…The advent of low cost, high throughput DNA sequencing has led to the availability of thousands of complete genome sequences for a wide variety of bacterial…”
Get full text
Journal Article