Search Results - "FitzPatrick, Vincent D"

High-throughput identification of human SNPs affecting regulatory element activity by van Arensbergen, Joris, Pagie, Ludo, FitzPatrick, Vincent D., de Haas, Marcel, Baltissen, Marijke P., Comoglio, Federico, van der Weide, Robin H., Teunissen, Hans, Võsa, Urmo, Franke, Lude, de Wit, Elzo, Vermeulen, Michiel, Bussemaker, Harmen J., van Steensel, Bas

“…Most of the millions of SNPs in the human genome are non-coding, and many overlap with putative regulatory elements. Genome-wide association studies (GWAS)…”
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Genome-wide mapping of autonomous promoter activity in human cells by van Arensbergen, Joris, FitzPatrick, Vincent D, de Haas, Marcel, Pagie, Ludo, Sluimer, Jasper, Bussemaker, Harmen J, van Steensel, Bas

“…The intrinsic strength of promoter sequences in driving transcription is measured across the human genome. Previous methods to systematically characterize…”
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Prediction of Nephrotoxicant Action and Identification of Candidate Toxicity-Related Biomarkers by Thukral, Sushil K., Nordone, Paul J., Hu, Rong, Sullivan, Leah, Galambos, Eric, Fitzpatrick, Vincent D., Healy, Laura, Bass, Michael B., Cosenza, Mary E., Afshari, Cynthia A.

“…A vast majority of pharmacological compounds and their metabolites are excreted via the urine, and within the complex structure of the kidney, the proximal…”
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Defining the fine structure of promoter activity on a genome-wide scale with CISSECTOR by FitzPatrick, Vincent D, Leemans, Christ, van Arensbergen, Joris, van Steensel, Bas, Bussemaker, Harmen J

“…Abstract Classic promoter mutagenesis strategies can be used to study how proximal promoter regions regulate the expression of particular genes of interest…”
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SelexGLM differentiates androgen and glucocorticoid receptor DNA-binding preference over an extended binding site by Zhang, Liyang, Martini, Gabriella D, Rube, H Tomas, Kribelbauer, Judith F, Rastogi, Chaitanya, FitzPatrick, Vincent D, Houtman, Jon C, Bussemaker, Harmen J, Pufall, Miles A

“…The DNA-binding interfaces of the androgen (AR) and glucocorticoid (GR) receptors are virtually identical, yet these transcription factors share only about a…”
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Inhibition of WISE Preserves Renal Allograft Function by XUEMING QIAN, XIAODONG YUAN, VALENTE, Eliane G, PRETORIUS, Jim, STENVENS, Jennitte L, TIPTON, Barbara, WINTERS, Aaron G, GRAHAM, Kevin, HARRISS, Lindsey, BAKER, Daniel M, DAMORE, Michael, SALIMI-MOOSAVI, Hossein, VONDERFECHT, Steven, YONGMING GAO, ELKHAL, Abdallah, PASZTY, Chris, SCOTT SIMONET, W, RICHARDS, William G, TULLIUS, Stefan G, XUPENG GE, LEE, Jae, JURISCH, Anke, LI ZHANG, YOU, Andrew, FITZPATRICK, Vincent D, WILLIAM, Alexia

“…Wnt-modulator in surface ectoderm (WISE) is a secreted modulator of Wnt signaling expressed in the adult kidney. Activation of Wnt signaling has been observed…”
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Predicting Autonomous Promoter Activity Based on Genome-Wide Modeling of Massively Parallel Reporter Data by FitzPatrick, Vincent D

“…Existing methods to systematically characterize sequence-intrinsic activity of promoters are limited by relatively low throughput and the length of sequences…”
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