Search Results - "FitzGerald, C"

The Therapeutic Potential of Metformin in Neurodegenerative Diseases by Rotermund, Carola, Machetanz, Gerrit, Fitzgerald, Julia C

“…The search for treatments for neurodegenerative diseases is a major concern in light of today's aging population and an increasing burden on individuals,…”
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Big data is crucial to the early detection of cancer by Fitzgerald, Rebecca C.

“…Among the many promises of big data, one of the most exciting could be the potential to unlock the detection of cancer before advanced malignancy ensures,…”
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Endoscopic Management of Early Adenocarcinoma and Squamous Cell Carcinoma of the Esophagus: Screening, Diagnosis, and Therapy by di Pietro, Massimiliano, Canto, Marcia I., Fitzgerald, Rebecca C.

“…Because the esophagus is easily accessible with endoscopy, early diagnosis and curative treatment of esophageal cancer is possible. However, diagnosis is often…”
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ΦCrAss001 represents the most abundant bacteriophage family in the human gut and infects Bacteroides intestinalis by Shkoporov, Andrey N., Khokhlova, Ekaterina V., Fitzgerald, C. Brian, Stockdale, Stephen R., Draper, Lorraine A., Ross, R. Paul, Hill, Colin

“…CrAssphages are an extensive and ubiquitous family of tailed bacteriophages, predicted to infect bacteria of the order Bacteroidales . Despite being found in…”
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Self-renewing endometrial epithelial organoids of the human uterus by Fitzgerald, Harriet C., Dhakal, Pramod, Behura, Susanta K., Schust, Danny J., Spencer, Thomas E.

“…The human endometrium is essential in providing the site for implantation and maintaining the growth and survival of the conceptus. An unreceptive endometrium…”
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Donor impurity band exchange in dilute ferromagnetic oxides by Coey, J. M. D, Venkatesan, M, Fitzgerald, C. B

“…Dilute ferromagnetic oxides having Curie temperatures far in excess of 300 K and exceptionally large ordered moments per transition-metal cation challenge our…”
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A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis by Absinta, Martina, Maric, Dragan, Gharagozloo, Marjan, Garton, Thomas, Smith, Matthew D., Jin, Jing, Fitzgerald, Kathryn C., Song, Anya, Liu, Poching, Lin, Jing-Ping, Wu, Tianxia, Johnson, Kory R., McGavern, Dorian B., Schafer, Dorothy P., Calabresi, Peter A., Reich, Daniel S.

“…Multiple sclerosis (MS) lesions that do not resolve in the months after they form harbour ongoing demyelination and axon degeneration, and are identifiable in…”
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Mesenchymal stromal cell therapy: progress in manufacturing and assessments of potency by ROBB, KEVIN P, FITZGERALD, JOAN C, BARRY, FRANK, VISWANATHAN, SOWMYA

“…Abstract Mesenchymal stromal cell (MSC) therapies have been pursued for a broad spectrum of indications but mixed reports on clinical efficacy have given rise…”
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Nucleosome-free Region Dominates Histone Acetylation in Targeting SWR1 to Promoters for H2A.Z Replacement by Ranjan, Anand, Mizuguchi, Gaku, FitzGerald, Peter C., Wei, Debbie, Wang, Feng, Huang, Yingzi, Luk, Ed, Woodcock, Christopher L., Wu, Carl

“…The histone variant H2A.Z is a genome-wide signature of nucleosomes proximal to eukaryotic regulatory DNA. Whereas the multisubunit chromatin remodeler SWR1 is…”
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In vitro models of the human endometrium: evolution and application for women's health by Fitzgerald, Harriet C., Schust, Danny J., Spencer, Thomas E.

“…The endometrium is the inner lining of the uterus that undergoes complex regeneration and differentiation during the human menstrual cycle. The process of…”
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scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation by Madissoon, E, Wilbrey-Clark, A, Miragaia, R J, Saeb-Parsy, K, Mahbubani, K T, Georgakopoulos, N, Harding, P, Polanski, K, Huang, N, Nowicki-Osuch, K, Fitzgerald, R C, Loudon, K W, Ferdinand, J R, Clatworthy, M R, Tsingene, A, van Dongen, S, Dabrowska, M, Patel, M, Stubbington, M J T, Teichmann, S A, Stegle, O, Meyer, K B

“…The Human Cell Atlas is a large international collaborative effort to map all cell types of the human body. Single-cell RNA sequencing can generate…”
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Anisotropic ferromagnetism in substituted zinc oxide by VENKATESAN, M, FITZGERALD, C. B, LUNNEY, J. G, COEY, J. M. D

“…Room-temperature ferromagnetism is observed in (110) oriented ZnO films made from targets containing 5 at. % of Sc, Ti, V, Fe, Co, or Ni, but not Cr, Mn, or Cu…”
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The landscape of somatic mutation in normal colorectal epithelial cells by Lee-Six, Henry, Olafsson, Sigurgeir, Ellis, Peter, Osborne, Robert J., Sanders, Mathijs A., Moore, Luiza, Georgakopoulos, Nikitas, Torrente, Franco, Noorani, Ayesha, Goddard, Martin, Robinson, Philip, Coorens, Tim H. H., O’Neill, Laura, Alder, Christopher, Wang, Jingwei, Fitzgerald, Rebecca C., Zilbauer, Matthias, Coleman, Nicholas, Saeb-Parsy, Kourosh, Martincorena, Inigo, Campbell, Peter J., Stratton, Michael R.

“…The colorectal adenoma–carcinoma sequence has provided a paradigmatic framework for understanding the successive somatic genetic changes and consequent clonal…”
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Delayed Antimicrobial Therapy Increases Mortality and Organ Dysfunction Duration in Pediatric Sepsis by Weiss, Scott L, Fitzgerald, Julie C, Balamuth, Fran, Alpern, Elizabeth R, Lavelle, Jane, Chilutti, Marianne, Grundmeier, Robert, Nadkarni, Vinay M, Thomas, Neal J

“…OBJECTIVES:Delayed antimicrobials are associated with poor outcomes in adult sepsis, but data relating antimicrobial timing to mortality and organ dysfunction…”
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The Evolving Genomic Landscape of Barrett’s Esophagus and Esophageal Adenocarcinoma by Contino, Gianmarco, Vaughan, Thomas L., Whiteman, David, Fitzgerald, Rebecca C.

“…We have recently gained unprecedented insight into genetic factors that determine risk for Barrett’s esophagus (BE) and progression to esophageal…”
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Global epidemiology of pediatric severe sepsis: the sepsis prevalence, outcomes, and therapies study by Weiss, Scott L, Fitzgerald, Julie C, Pappachan, John, Wheeler, Derek, Jaramillo-Bustamante, Juan C, Salloo, Asma, Singhi, Sunit C, Erickson, Simon, Roy, Jason A, Bush, Jenny L, Nadkarni, Vinay M, Thomas, Neal J

“…Limited data exist about the international burden of severe sepsis in critically ill children. To characterize the global prevalence, therapies, and outcomes…”
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Drive-by scour monitoring of railway bridges using a wavelet-based approach by Fitzgerald, Paul C., Malekjafarian, Abdollah, Cantero, Daniel, OBrien, Eugene J., Prendergast, Luke J.

“…•A drive-by approach is used to detect scour of a railway bridge.•Continuous Wavelet Transform is applied to simulated train acceleration signals.•Scour…”
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DeepHarmony: A deep learning approach to contrast harmonization across scanner changes by Dewey, Blake E., Zhao, Can, Reinhold, Jacob C., Carass, Aaron, Fitzgerald, Kathryn C., Sotirchos, Elias S., Saidha, Shiv, Oh, Jiwon, Pham, Dzung L., Calabresi, Peter A., van Zijl, Peter C.M., Prince, Jerry L.

“…Magnetic resonance imaging (MRI) is a flexible medical imaging modality that often lacks reproducibility between protocols and scanners. It has been shown that…”
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Unexpected magnetism in a dielectric oxide by Venkatesan, M., Fitzgerald, C. B., Coey, J. M. D.

“…It is generally accepted that magnetic order in an insulator requires the cation to have partially filled shells of d or f electrons. Here we show that thin…”
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Organoid cultures recapitulate esophageal adenocarcinoma heterogeneity providing a model for clonality studies and precision therapeutics by Li, Xiaodun, Francies, Hayley E., Secrier, Maria, Perner, Juliane, Miremadi, Ahmad, Galeano-Dalmau, Núria, Barendt, William J., Letchford, Laura, Leyden, Genevieve M., Goffin, Emma K., Barthorpe, Andrew, Lightfoot, Howard, Chen, Elisabeth, Gilbert, James, Noorani, Ayesha, Devonshire, Ginny, Bower, Lawrence, Grantham, Amber, MacRae, Shona, Grehan, Nicola, Wedge, David C., Fitzgerald, Rebecca C., Garnett, Mathew J.

“…Esophageal adenocarcinoma (EAC) incidence is increasing while 5-year survival rates remain less than 15%. A lack of experimental models has hampered progress…”
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