Search Results - "Fitz, L."

Proteomic analysis of serum and sputum analytes distinguishes controlled and poorly controlled asthmatics by Kasaian, M. T., Lee, J., Brennan, A., Danto, S. I., Black, K. E., Fitz, L., Dixon, A. E.

“…Summary Background A major goal of asthma therapy is to achieve disease control, with maintenance of lung function, reduced need for rescue medication, and…”
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Issues, Interactions, and Group Images as Mechanisms of Affective Polarization in Two Environmental Conflicts in Argentina by Fitz Herbert, Arturo L., Elizalde Acevedo, Luciano H.

“…Affective polarization happens when groups develop mutual negative perceptions and feelings. This phenomenon has raised concern among journalists, opinion…”
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Conflict narrative, stigmatisation and strategic behaviour of religious scientists in the Argentinean scientific field by Fitz Herbert, Arturo L., Rivera, Reynaldo, Ketelhohn, Frank, Elsdon-Baker, Fern

“…Recent surveys show that most scientists do not perceive a conflict between science and religion. However, in many Western societies the “conflict narrative”…”
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Association between serum interleukin‐17A and clinical response to tofacitinib and etanercept in moderate to severe psoriasis by Fitz, L., Zhang, W., Soderstrom, C., Fraser, S., Lee, J., Quazi, A., Wolk, R., Mebus, C. A., Valdez, H., Berstein, G.

“…Summary Background Psoriasis is a systemic inflammatory disease with a pathophysiology involving interleukin (IL)‐17. Tofacitinib is an oral Janus kinase…”
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Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation by Freeman, G J, Long, A J, Iwai, Y, Bourque, K, Chernova, T, Nishimura, H, Fitz, L J, Malenkovich, N, Okazaki, T, Byrne, M C, Horton, H F, Fouser, L, Carter, L, Ling, V, Bowman, M R, Carreno, B M, Collins, M, Wood, C R, Honjo, T

“…PD-1 is an immunoinhibitory receptor expressed by activated T cells, B cells, and myeloid cells. Mice deficient in PD-1 exhibit a breakdown of peripheral…”
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A Multiscale Model of Interleukin‐6–Mediated Immune Regulation in Crohn's Disease and Its Application in Drug Discovery and Development by Dwivedi, G, Fitz, L, Hegen, M, Martin, SW, Harrold, J, Heatherington, A, Li, C

“…In this study, we have developed a multiscale systems model of interleukin (IL)‐6–mediated immune regulation in Crohn's disease, by integrating intracellular…”
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Evaluation of health literacy tools for correct prescription understanding by Loueng, Jane L, Fitz, Alicia L., PharmD, Maack, Brody J., PharmD, Miller, Donald R., PharmD

“…Abstract Objectives To evaluate two brief health literacy prediction tools for understanding of a prescription label and using a drug correctly. Methods…”
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Identification and purification of natural killer cell stimulatory factor (NKSF), a cytokine with multiple biologic effects on human lymphocytes by KOBAYASHI, M, FITZ, L, FRYAN, M, HEWICK, R. M, CLARK, S. C, CHAN, S, LOUDON, R, SHERMAN, F, PERUSSIA, B, TRINCHIERI, G

“…We have identified and purified a novel cytokine, NK cell stimulatory factor (NKSF), from the cell-free supernatant fluid of the phorbol diester-induced…”
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Activation-induced cellular accumulation of histamine in immature but not mature murine mast cells by Fitz, L. J, Brennan, A, Wood, C. R, Goldman, S. J, Kasaian, M. T

“…Mast cell activation involves the rapid release of inflammatory mediators, including histamine, from intracellular granules. The cells are capable of…”
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Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells by Wolf, SF, Temple, PA, Kobayashi, M, Young, D, Dicig, M, Lowe, L, Dzialo, R, Fitz, L, Ferenz, C, Hewick, RM

“…Previously we have reported the purification and characterization of a novel cytokine from an EBV-transformed B cell line, RPMI 8866. This factor, termed…”
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Multiplex proteomics identifies novel CSF and plasma biomarkers of early Alzheimer's disease by Whelan, Christopher D, Mattsson, Niklas, Nagle, Michael W, Vijayaraghavan, Swetha, Hyde, Craig, Janelidze, Shorena, Stomrud, Erik, Lee, Julie, Fitz, Lori, Samad, Tarek A, Ramaswamy, Gayathri, Margolin, Richard A, Malarstig, Anders, Hansson, Oskar

“…To date, the development of disease-modifying therapies for Alzheimer's disease (AD) has largely focused on the removal of amyloid beta Aβ fragments from the…”
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Characterization of murine Flt4 ligand/VEGF-C by FITZ, L. J, MORRIS, J. C, CIARLETTA, A, GIANNOTTI, J, FINNERTY, H, ZOLLNER, R, BEIER, D. R, LEAK, L. V, TURNER, K. J, WOOD, C. R, TOWLER, P, LONG, A, BURGESS, P, GRECO, R, WANG, J, GASSAWAY, R, NICKBARG, E, KOVACIC, S

“…Flt4 is a receptor protein tyrosine kinase that is expressed in the adult lymphatic endothelium and high endothelial venules. We have used a BIAcore assay to…”
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Induction of a Secreted Protein by the Myxoid Liposarcoma Oncogene by Kuroda, Masahiko, Wang, XiaoZhong, Sok, John, Yin Yin, Chung, Peter, Giannotti, JoAnn W., Jacobs, Kenneth A., Fitz, Lori J., Murtha-Riel, Patricia, Turner, Katherine J., Ron, David

“…The TLS-CHOP oncoprotein, found in the majority of human myxoid liposarcomas, consists of a fusion between the transcription factor CHOP/GADD153 and the N…”
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276 Reduction of cardiovascular disease-associated proteins in blood of psoriasis patients after 1-month treatment with tofacitinib or etanercept by Kim, J., Correa-da Rosa, J., Lee, J., Tomalin, L., Lowes, M.A., Fitz, L., Berstein, G., Valdez, H., Wolk, R., Suarez-Farinas, M., Krueger, J.G.

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545 Precision medicine in psoriasis: machine learning and proteomics join forces to develop a blood-based test to predict response to tofacitinib or Etanercept in psoriasis patients by Kim, J., Correa-da Rosa, J., Lee, J., Tomalin, L., Lowes, M.A., Fitz, L., Berstein, G., Valdez, H., Wolk, R., Krueger, J.G., Suarez-Farinas, M.

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PD‐1:PD‐L inhibitory pathway affects both CD4+ and CD8+ T cells and is overcome by IL‐2 by Carter, Laura L., Fouser, Lynette A., Jussif, Jason, Fitz, Lori, Deng, Bija, Wood, Clive R., Collins, Mary, Honjo, Tasuku, Freeman, Gordon J., Carreno, Beatriz M.

“…Programmed death‐1 (PD‐1) is an immunoreceptor tyrosine‐based inhibitory motif (ITIM)‐containing receptor expressed upon T cell activation. PD‐1–/– animals…”
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Integrated photonic inverter with gain by Fitz, J.L., Beard, W.T., Horst, S.C., Smith, S.D.

“…Photonic integrated circuits (PICs) require inverting gates with gain greater than one to enable logic functionality with fanout and cascade. Optically…”
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Interleukin-4 (IL-4) in combination with IL-11 or IL-6 reverses the inhibitory effect of IL-3 on early B lymphocyte development by Neben, S, Donaldson, D, Fitz, L, Calvetti, J, Neben, T, Turner, K, Hirayama, F, Ogawa, M

“…We have previously described a two-step methylcellulose culture system in which individual primitive progenitors from 5-fluorouracil (5-FU)-treated mice were…”
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High-reflectance dielectric mirrors deposited by plasma-enhanced chemical vapor deposition on GaAs-AlGaAs semiconductor lasers with inductively coupled plasma etched facets by Horst, S.C., Hinkel, D.S., Fitz, J.L., Turk, H.

“…High-reflectance dielectric mirrors (HRDMs) have been deposited on the etched facets of edge-emitting semiconductor ridge lasers. Dry etching using an…”
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Catalytic Domain Crystal Structure of Protein Kinase C-θ (PKCθ) by Xu, Zhang-Bao, Chaudhary, Divya, Olland, Stephane, Wolfrom, Scott, Czerwinski, Robert, Malakian, Karl, Lin, Laura, Stahl, Mark L., Joseph-McCarthy, Diane, Benander, Christina, Fitz, Lori, Greco, Rita, Somers, William S., Mosyak, Lidia

“…A member of the novel protein kinase C (PKC) subfamily, PKCθ, is an essential component of the T cell synapse and is required for optimal T cell activation and…”
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