Search Results - "Fittje, Pia"
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HIV-1 Nef-mediated downregulation of CD155 results in viral restriction by KIR2DL5+ NK cells
Published in PLoS pathogens (01-06-2022)“…Antiviral NK cell activity is regulated through the interaction of activating and inhibitory NK cell receptors with their ligands on infected cells. HLA class…”
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Host KIR/HLA-C Genotypes Determine HIV-Mediated Changes of the NK Cell Repertoire and Are Associated With Vpu Sequence Variations Impacting Downmodulation of HLA-C
Published in Frontiers in immunology (15-07-2022)“…NK cells play a pivotal role in viral immunity, utilizing a large array of activating and inhibitory receptors to identify and eliminate virus-infected cells…”
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The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56bright NK cells
Published in Frontiers in immunology (09-02-2023)“…The crosstalk between NK cells and their surrounding environment is enabled through activating and inhibitory receptors, which tightly control NK cell…”
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4
Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
Published in EMBO reports (03-08-2022)“…NK cells utilize a large array of receptors to screen their surroundings for aberrant or virus‐infected cells. Given the vast diversity of receptors expressed…”
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5
Interactions Between KIR3DS1 and HLA-F Activate Natural Killer Cells to Control HCV Replication in Cell Culture
Published in Gastroenterology (New York, N.Y. 1943) (01-11-2018)“…Killer-cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer (NK) cells. Binding of KIR3DS1 to its recently…”
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6
The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56 bright NK cells
Published in Frontiers in immunology (2023)“…The crosstalk between NK cells and their surrounding environment is enabled through activating and inhibitory receptors, which tightly control NK cell…”
Get full text
Journal Article