Search Results - "Fitt, John J"

Identification of Dipeptidyl Nitriles as Potent and Selective Inhibitors of Cathepsin B through Structure-Based Drug Design by Greenspan, Paul D, Clark, Kirk L, Tommasi, Ruben A, Cowen, Scott D, McQuire, Leslie W, Farley, David L, van Duzer, John H, Goldberg, Ronald L, Zhou, Huanghai, Du, Zhengming, Fitt, John J, Coppa, David E, Fang, Zheng, Macchia, William, Zhu, Lijuan, Capparelli, Michael P, Goldstein, Robert, Wigg, Andrew M, Doughty, John R, Bohacek, Regine S, Knap, Ania K

“…Cathepsin B is a member of the papain superfamily of cysteine proteases and has been implicated in the pathology of numerous diseases, including arthritis and…”
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alpha.-Alkylation and Michael addition of amino acids - a practical method by Fitt, John J, Gschwend, Heinz W

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Lithiation of N,N-dimethyl-3-(phenylthio)-2-propenylamine by Fitt, John J, Gschwend, Heinz W

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Carboxy-Substituted Cinnamides:  A Novel Series of Potent, Orally Active LTB4 Receptor Antagonists by Greenspan, Paul D, Fujimoto, Roger A, Marshall, Paul J, Raychaudhuri, Anil, Lipson, Kenneth E, Zhou, Huanghai, Doti, Robert A, Coppa, David E, Zhu, Lijuan, Pelletier, Roberta, Uziel-Fusi, Susan, Jackson, Robert H, Chin, Michael H, Kotyuk, Bernard L, Fitt, John J

“…A series of carboxy-substituted cinnamides were investigated as antagonists of the human cell surface leukotriene B4 (LTB4) receptor. Binding was determined…”
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Reaction of n-, sec-, and tert-butyllithium with dimethoxyethane (DME): a correction by Fitt, John J, Gschwend, Heinz W

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Dimetalation of N-tert-butylmethacrylamide: a new synthetic reagent by Fitt, John J, Gschwend, Heinz W

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Lithiation of N,N-dimethylmethallylamine by Fitt, John J, Gschwend, Heinz W

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Ortho lithiation of thiobenzamides by Fitt, John J, Gschwend, Heinz W

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O-(1-Alkyl- or arylthioalkyl)hydroxylamines. New class of oxime reagents, their preparation, and synthetic utility by Vlattas, Isidoros, DellaVecchia, Laurence, Fitt, John J

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Practical synthesis of 9-chloro-7-(o-fluorophenyl)-5H-dibenz[c,e]azepine by Fitt, John J, Gschwend, Heinz W, Hamdan, Ali, Boyer, Stephen K, Haider, Hasan M

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Total synthesis of DL-prostaglandin E1 by Finch, Neville, DellaVecchia, L, Fitt, John J, Stephani, Ralph, Vlattas, I

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Total synthesis of dl-9-deoxyprostaglandin E1 by Finch, Neville, Fitt, John J, Hsu, Iva H. S

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Cyclopentenone synthesis by directed cyclization by Finch, Neville, Fitt, John J, Hsu, Iva H. C

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Carboxy-Substituted Cinnamides:  A Novel Series of Potent, Orally Active LTB 4 Receptor Antagonists by Greenspan, Paul D., Fujimoto, Roger A., Marshall, Paul J., Raychaudhuri, Anil, Lipson, Kenneth E., Zhou, Huanghai, Doti, Robert A., Coppa, David E., Zhu, Lijuan, Pelletier, Roberta, Uziel-Fusi, Susan, Jackson, Robert H., Chin, Michael H., Kotyuk, Bernard L., Fitt, John J.

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