Search Results - "Fitches, Elaine C."

A Systematic Study of RNAi Effects and dsRNA Stability in Tribolium castaneum and Acyrthosiphon pisum , Following Injection and Ingestion of Analogous dsRNAs by Cao, Min, Gatehouse, John A, Fitches, Elaine C

“…RNA interference (RNAi) effects in insects are highly variable and may be largely dependent upon the stability of introduced double-stranded RNAs to digestion…”
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Heterologous production of the insecticidal pea seed albumin PA1 protein by Pichia pastoris and protein engineering to potentiate aphicidal activity via fusion to snowdrop lectin Galanthus nivalis agglutinin; GNA by De-Thier, Jake S, Pyati, Prashant, Bell, Jack, Readshaw, Jennifer J, Brown, Adrian P, Fitches, Elaine C

“…New bioinsecticides with novel modes of action are urgently needed to minimise the environmental and safety hazards associated with the use of synthetic…”
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Fusion to snowdrop lectin magnifies the oral activity of insecticidal ω-Hexatoxin-Hv1a peptide by enabling its delivery to the central nervous system by Fitches, Elaine C, Pyati, Prashant, King, Glenn F, Gatehouse, John A

“…The spider-venom peptide ω-hexatoxin-Hv1a (Hv1a) targets insect voltage-gated calcium channels, acting directly at sites within the central nervous system. It…”
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The insecticidal activity of recombinant nemertide toxin α-1 from Lineus longissimus towards pests and beneficial species by Bell, Jack, Sukiran, Nur Afiqah, Walsh, Stephen, Fitches, Elaine C.

“…The nemertide toxins from the phylum Nemertea are a little researched family of neurotoxins with potential for development as biopesticides. Here we report the…”
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Systemic RNAi in the small hive beetle Aethina tumida Murray (Coleoptera: Nitidulidae), a serious pest of the European honey bee Apis mellifera by Powell, Michelle E, Bradish, Hannah M, Gatehouse, John A, Fitches, Elaine C

“…BACKGROUND Aethina tumida is a serious pest of the European honey bee (Apis mellifera) in North America and Australia. Here we investigate whether Laccase 2,…”
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Enhancing the oral and topical insecticidal efficacy of a commercialized spider venom peptide biopesticide via fusion to the carrier snowdrop lectin (Galanthus nivalis agglutinin) by Sukiran, Nur Afiqah, Pyati, Prashant, Willis, Caitlin E, Brown, Adrian P, Readshaw, Jennifer J, Fitches, Elaine C

“…BACKGROUND Spear®‐T sold as a contact foliar spray for the control of glasshouse pests such as aphids, thrips, spider mites and whiteflies, contains the…”
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Spider venom neurotoxin based bioinsecticides: A novel bioactive for the control of the Asian citrus psyllid Diaphorina citri (Hemiptera) by Miranda, Marcelo P., Fitches, Elaine C., Sukiran, Nur Afiqah, Eduardo, Wellington I., Garcia, Rafael B., Jaciani, Fabrício J., Readshaw, Jennifer J., Bell, Jack, Peña, Leandro

“…The Asian citrus psyllid, Diaphorina citri Kuwayama (Hemiptera: Psyllidae), is a key vector of the phloem-limited bacteria Candidatus Liberibacter asiaticus…”
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Novel biopesticide based on a spider venom peptide shows no adverse effects on honeybees by Nakasu, Erich Y. T., Williamson, Sally M., Edwards, Martin G., Fitches, Elaine C., Gatehouse, John A., Wright, Geraldine A., Gatehouse, Angharad M. R.

“…Evidence is accumulating that commonly used pesticides are linked to decline of pollinator populations; adverse effects of three neonicotinoids on bees have…”
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Demonstrating the potential of a novel spider venom-based biopesticide for target-specific control of the small hive beetle, a serious pest of the European honeybee by Powell, Michelle E., Bradish, Hannah M., Cao, Min, Makinson, Rebecca, Brown, Adrian P., Gatehouse, John A., Fitches, Elaine C.

“…The parasitic small hive beetle ( Aethina tumida ) feeds on pollen, honey and brood of the European honey bee ( Apis mellifera ); establishment in North…”
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Insecticidal activity of scorpion toxin (ButaIT) and snowdrop lectin (GNA) containing fusion proteins towards pest species of different orders by Fitches, Elaine C, Bell, Howard A, Powell, Michelle E, Back, Emma, Sargiotti, Chiara, Weaver, Robert J, Gatehouse, John A

“…BACKGROUND: The toxicity of a fusion protein, ButalT/GNA, comprising a venom toxin (ButaIT) derived from the red scorpion, Mesobuthus tamulus (F.), and…”
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Sublethal effects of the insecticidal fusion protein ω‐ACTX‐Hv1a/GNA on the parasitoid Eulophus pennicornis via its host Lacanobia oleracea by Nakasu, Erich YT, Karamaouna, Filitsa, Partsinevelos, Georgios K, Abd El Halim, Hesham M, Fitches, Elaine C, Pyati, Prashant, Gatehouse, John A, Gatehouse, Angharad MR, Edwards, Martin G

“…BACKGROUND: The neurotoxin peptide ω‐ACTX‐Hv1a, fused to the carrier molecule GNA, presents potential for insect control as a biopesticide, being orally toxic…”
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Insecticidal spider venom toxin fused to snowdrop lectin is toxic to the peach-potato aphid, Myzus persicae (Hemiptera: Aphididae) and the rice brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae) by Down, R.E, Fitches, E.C, Wiles, D.P, Corti, P, Bell, H.A, Gatehouse, J.A, Edwards, J.P

“…The SFI1/GNA fusion protein, comprising of snowdrop lectin (Galanthus nivalis agglutinin, GNA) fused to an insecticidal spider venom neurotoxin (Segestria…”
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snowdrop lectin Galanthus nivalis agglutinin (GNA) and a fusion protein ButaIT/GNA have a differential affect on a pest noctuid Lacanobia oleracea and the ectoparasitoid Eulophus pennicornis by WAKEFIELD, MAUREEN E, FITCHES, ELAINE C, BELL, HOWARD A, GATEHOUSE, ANGHARAD M.R

“…Fusion proteins have considerable potential as novel insect control agents because they enable the oral delivery of insecticidal peptides to the haemolymph of…”
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Effect of dietary cowpea trypsin inhibitor (CpTI) on the growth and development of the tomato moth Lacanobia oleracea (Lepidoptera: Noctuidae) and on the success of the gregarious ectoparasitoid Eulophus pennicornis (Hymenoptera: Eulophidae) by Bell, Howard A, Fitches, Elaine C, Down, Rachel E, Ford, Louise, Marris, Gay C, Edwards, John P, Gatehouse, John A, Gatehouse, Angharad M R

“…Cowpea trypsin inhibitor (CpTI) was shown to have a deleterious effect on the growth and development of larvae of the tomato moth, Lacanobia oleracea, when…”
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Ex-ante life cycle impact assessment of insect based feed production in West Africa by Roffeis, Martin, Fitches, Elaine C., Wakefield, Maureen E., Almeida, Joana, Alves Valada, Tatiana R., Devic, Emilie, Koné, N’Golopé, Kenis, Marc, Nacambo, Saidou, Koko, Gabriel K.D., Mathijs, Erik, Achten, Wouter M.J., Muys, Bart

“…•Study explores the environmental impact of insect based feeds (IBFs) in West Africa.•Three IBF production models are ex-ante assessed using life cycle…”
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Systemic RNAi in the small hive beetle Aethina tumida Murray (Coleoptera: Nitidulidae), a serious pest of the European honey bee Apis mellifera: Systemic RNAi in the small hive beetle Aethina tumida by Powell, Michelle E, Bradish, Hannah M, Gatehouse, John A, Fitches, Elaine C

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Effect of dietary cowpea trypsin inhibitor (CpTI) on the growth and development of the tomato mothLacanobia oleracea (Lepidoptera: Noctuidae) and on the success of the gregarious ectoparasitoidEulophus pennicornis (Hymenoptera: Eulophidae) by Bell, Howard A, Fitches, Elaine C, Down, Rachel E, Ford, Louise, Marris, Gay C, Edwards, John P, Gatehouse, John A, Gatehouse, Angharad M?R

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Novel biopesticide based on a spider venom peptide shows no adverse effects on honeybees by Nakasu, Erich Y. T., Williamson, Sally M., Edwards, Martin G., Fitches, Elaine C., Gatehouse, John A., Wright, Geraldine A., Gatehouse, Angharad M. R.

“…Evidence is accumulating that commonly used pesticides are linked to decline of pollinator populations; adverse effects of three neonicotinoids on bees have…”
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Fusion to Snowdrop Lectin Magnifies the Oral Activity of Insecticidal [omega]-Hexatoxin-Hv1a Peptide by Enabling Its Delivery to the Central Nervous System by Fitches, Elaine C, Pyati, Prashant, King, Glenn F, Gatehouse, John A

“…Background The spider-venom peptide [omega]-hexatoxin-Hv1a (Hv1a) targets insect voltage-gated calcium channels, acting directly at sites within the central…”
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Sublethal effects of the insecticidal fusion protein ω -ACTX-Hv1a/GNA on the parasitoid Eulophus pennicornis via its host Lacanobia oleracea: Effects of novel insecticide on the parasitoid E. pennicornis via its host L. oleracea by Nakasu, Erich YT, Karamaouna, Filitsa, Partsinevelos, Georgios K, Abd El Halim, Hesham M, Fitches, Elaine C, Pyati, Prashant, Gatehouse, John A, Gatehouse, Angharad MR, Edwards, Martin G

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