Search Results - "Fisniku, Leonora"
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Gray matter atrophy is related to long-term disability in multiple sclerosis
Published in Annals of neurology (01-09-2008)“…Objective To determine the relation of gray matter (GM) and white matter (WM) brain volumes, and WM lesion load, with clinical outcomes 20 years after first…”
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Management approach including pembrolizumab for fingolimod-associated progressive multifocal leukoencephalopathy in a patient with relapsing-remitting multiple sclerosis
Published in Multiple sclerosis (01-02-2023)“…A 62-year-old man with relapsing-remitting multiple sclerosis developed progressive multifocal leukencephalopathy (PML) after 6 years on fingolimod. The…”
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3
Do Early Relapses Predict the Risk of Long‐Term Relapsing Disease in an Adult and Paediatric Cohort with MOGAD?
Published in Annals of neurology (01-09-2023)“…Objective Myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) can be monophasic or relapsing, with early relapse being a feature. However,…”
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Factors Associated With Relapse and Treatment of Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease in the United Kingdom
Published in JAMA network open (04-01-2022)“…Longer-term outcomes and risk factors associated with myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) are not well established. To…”
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MS care: integrating advanced therapies and holistic management
Published in Frontiers in neurology (30-01-2024)“…Lifestyle and environmental factors are key determinants in disease causality and progression in neurological conditions, including multiple sclerosis (MS)…”
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Acute Inflammatory Diseases of the Central Nervous System After SARS-CoV-2 Vaccination
Published in Neurology : neuroimmunology & neuroinflammation (01-01-2023)“…Acute inflammatory CNS diseases include neuromyelitis optica spectrum disorders (NMOSDs) and myelin oligodendrocyte glycoprotein antibody-associated disease…”
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056 OCT screening prior to starting fingolimod: is it truly justified?
Published in Journal of neurology, neurosurgery and psychiatry (01-06-2022)“…Background and Aim Fingolimod, an oral immunomodulating drug is used in the management of relaps- ing-remitting MS (RRMS)-patients. Fingolimod-related macular…”
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TI-relaxation time changes over five years in relapsing-remitting multiple sclerosis
Published in Multiple sclerosis (01-04-2010)“…The pathological effects of multiple sclerosis are not confined to lesions; tissues that appear normal on conventional magnetic resonance imaging scans are…”
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072 The oblique path of a transverse lesion
Published in Journal of neurology, neurosurgery and psychiatry (01-06-2022)“…A 38-year-old man presented in September 2016 with left hand numbness which progressed over 2 days to disabling weakness of his left arm and leg. He initially…”
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006 Secondary amenorrhea related to natalizumab
Published in Journal of neurology, neurosurgery and psychiatry (01-06-2022)“…BackgroundAdverse events are inevitable for many pharmacological interventions, including disease modifying treatment (DMT) in Multiple Sclerosis (MS)…”
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005 Infusion associated reactions in ocrelizumab-treated multiple sclerosis patients
Published in Journal of neurology, neurosurgery and psychiatry (01-06-2022)“…Background and aimsInfusion-associated-reactions (IARs) are a common side effect (SE) of Ocrelizumab, a disease modifying therapy (DMT) licensed for treatment…”
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Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study
Published in The Lancet. Psychiatry (01-10-2020)“…Concerns regarding potential neurological complications of COVID-19 are being increasingly reported, primarily in small series. Larger studies have been…”
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201 Alemtuzumab related HPV infection and cervical dysplasia: real world data
Published in Journal of neurology, neurosurgery and psychiatry (01-12-2019)“…BackgroundAlemtuzumab a disease-modifying-therapy for relapsing-remitting Multiple Sclerosis (RRMS) increases the risk of Human Papilloma Virus (HPV) and…”
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14
Po120 CMT1A and co-existing primary progressive multiple sclerosis
Published in Journal of neurology, neurosurgery and psychiatry (01-12-2017)“…A 56-year-old lady presented with a 3 year history of slowly worsening mobility and balance, spasms, and sphincter dysfunction. At 46 she received a…”
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215 Demographic, clinical and paraclinical features in a subgroup of patients with NMOSD
Published in Journal of neurology, neurosurgery and psychiatry (01-12-2019)“…BackgroundNeuromyelitis optica spectrum disorder (NMOSD) is an autoimmune, inflammatory condition more commonly distinguished from multiple sclerosis (MS)…”
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16
The impact of smoking cessation on multiple sclerosis disease progression
Published in Brain (London, England : 1878) (24-05-2022)“…The negative impact of smoking in multiple sclerosis is well established; however, there is much less evidence as to whether smoking cessation is beneficial to…”
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TWO CONCURRENT PARANEOPLASTIC SYNDROMES-USING OCCAM'S RAZOR
Published in Journal of neurology, neurosurgery and psychiatry (01-10-2014)“…A 58 year old lady presented with rapidly progressive symmetrical limb weakness over a few weeks. She had a background of WHO-B2 thymoma diagnosed in 2005 with…”
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PO117 Regional efficacy of fingolimod in multiple sclerosis
Published in Journal of neurology, neurosurgery and psychiatry (01-12-2017)“…BackgroundFingolimod is approved in England as second-line treatment for highly active relapsing-remitting multiple sclerosis (RRMS).ObjectivesTo evaluate the…”
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Cardiovascular risk factors in secondary progressive multiple sclerosis: A cross‐sectional analysis from the MS‐STAT2 randomized controlled trial
Published in European journal of neurology (01-09-2023)“…Background and purpose There is increasing evidence that cardiovascular risk (CVR) contributes to disability progression in multiple sclerosis (MS). CVR is…”
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20
A study of referral bias in NMOSD and MOGAD cohorts
Published in Multiple sclerosis and related disorders (01-05-2024)“…•Relapsing rate in MOGAD is overestimated in cohorts from specialised centres.•Clinical presentation does not differ across local, regional, or national…”
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