Search Results - "Fishman, Kaitlyn M."

Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia by Fathi, Amir T, Wander, Seth A, Blonquist, Traci M, Brunner, Andrew M, Amrein, Philip C, Supko, Jeffrey, Hermance, Nicole M, Manning, Amity L, Sadrzadeh, Hossein, Ballen, Karen K, Attar, Eyal C, Graubert, Timothy A, Hobbs, Gabriela, Joseph, Christelle, Perry, Ashley M, Burke, Meghan, Silver, Regina, Foster, Julia, Bergeron, Meghan, Ramos, Aura Y, Som, Tina T, Fishman, Kaitlyn M, McGregor, Kristin L, Connolly, Christine, Neuberg, Donna S, Chen, Yi-Bin

“…Aberrant expression of aurora kinase A is implicated in the genesis of various neoplasms, including acute myeloid leukemia. Alisertib, an aurora A kinase…”
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Cabozantinib is well tolerated in acute myeloid leukemia and effectively inhibits the resistance‐conferring FLT3/tyrosine kinase domain/F691 mutation by Fathi, Amir T., Blonquist, Traci M., Hernandez, Daniela, Amrein, Philip C., Ballen, Karen K., McMasters, Malgorzata, Avigan, David E., Joyce, Robin, Logan, Emma K., Hobbs, Gabriela, Brunner, Andrew M., Joseph, Christelle, Perry, Ashley M., Burke, Meghan, Behnan, Tanya, Foster, Julia, Bergeron, Meghan K., Moran, Jenna A., Ramos, Aura Y., Som, Tina T., Rae, Jessica, Fishman, Kaitlyn M., McGregor, Kristin L., Connolly, Christine, Neuberg, Donna S., Levis, Mark J.

“…BACKGROUND Cabozantinib, a tyrosine kinase inhibitor of FMS‐like tyrosine kinase 3 (FLT3), MET, AXL, vascular endothelial growth factor receptor, and KIT, is…”
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Alisertib plus induction chemotherapy in previously untreated patients with high-risk, acute myeloid leukaemia: a single-arm, phase 2 trial by Brunner, Andrew M, Blonquist, Traci M, DeAngelo, Daniel J, McMasters, Malgorzata, Fell, Geoffrey, Hermance, Nicole M, Winer, Eric S, Lindsley, R Coleman, Hobbs, Gabriela S, Amrein, Philip C, Hock, Hanno R, Steensma, David P, Garcia, Jacqueline S, Luskin, Marlise R, Stone, Richard M, Ballen, Karen K, Rosenblatt, Jacalyn, Avigan, David, Nahas, Myrna R, Mendez, Lourdes M, McAfee, Steven L, Moran, Jenna A, Bergeron, Meghan, Foster, Julia, Bertoli, Christina, Manning, Amity L, McGregor, Kristin L, Fishman, Kaitlyn M, Kuo, Frank C, Baltay, Michele T, Macrae, Molly, Burke, Meghan, Behnan, Tanya, Wey, Margaret C, Som, Tina T, Ramos, Aura Y, Rae, Jessica, Lombardi Story, Jennifer, Nelson, Nicole, Logan, Emma, Connolly, Christine, Neuberg, Donna S, Chen, Yi-Bin, Graubert, Timothy A, Fathi, Amir T

“…Increased aurora A kinase (AAK) expression occurs in acute myeloid leukaemia; AAK inhibition is a promising therapeutic target in this disease. We therefore…”
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