Search Results - "Fishman, Harvey A"

Thin collagen film scaffolds for retinal epithelial cell culture by Lu, James T, Lee, Christina J, Bent, Stacey F, Fishman, Harvey A, Sabelman, Eric E

“…Abstract Collagen films have been used in biological implantation and surgical grafts. The development of thin collagen films on the order of 10 μm thick that…”
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Localized Chemical Release from an Artificial Synapse Chip by Peterman, Mark C., Noolandi, Jaan, Blumenkranz, Mark S., Fishman, Harvey A., Langer, Robert S.

“…A device that releases chemical compounds in small volumes and at multiple, well defined locations would be a powerful tool for clinical therapeutics and…”
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Neural Stimulation with a Carbon Nanotube Microelectrode Array by Wang, Ke, Fishman, Harvey A, Dai, Hongjie, Harris, James S

“…We present a novel prototype neural interface using vertically aligned multiwalled carbon nanotube (CNT) pillars as microelectrodes. Functionalized hydrophilic…”
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Localized Neurotransmitter Release for Use in a Prototype Retinal Interface by Peterman, Mark C, Bloom, David M, Lee, Christina, Bent, Stacey F, Marmor, Michael F, Blumenkranz, Mark S, Fishman, Harvey A

“…Current neural prostheses use electricity as the mode of stimulation, yet information transfer in neural circuitry is primarily through chemical transmitters…”
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The Artificial Synapse Chip: A Flexible Retinal Interface Based on Directed Retinal Cell Growth and Neurotransmitter Stimulation by Peterman, Mark C., Mehenti, Neville Z., Bilbao, Kalayaan V., Lee, Christina J., Leng, Theodore, Noolandi, Jaan, Bent, Stacey F., Blumenkranz, Mark S., Fishman, Harvey A.

“…:  The Artificial Synapse Chip is an evolving design for a flexible retinal interface that aims to improve visual resolution of an electronic retinal…”
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Carbon nanotube bucky paper as an artificial support membrane for retinal cell transplantation by Leng, Theodore, Fishman, Harvey A

“…Transplantation of epithelial cells on a substrate to rescue diseased retinal cells is an experimental therapy for age-related macular degeneration. Carbon…”
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Determination of human lens capsule permeability and its feasibility as a replacement for Bruch's membrane by Lee, Christina J., Vroom, Jonathan A., Fishman, Harvey A., Bent, Stacey F.

“…We have investigated human anterior lens capsule as a potential replacement for Bruch's membrane as a treatment for age-related macular degeneration. Any…”
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Spatial cues for the enhancement of retinal pigment epithelial cell function in potential transplants by Lee, Christina J, Fishman, Harvey A, Bent, Stacey F

“…Abstract Retinal pigment epithelial (RPE) cellular morphology and function are vital to the health of the retina. In age-related macular degeneration, RPE…”
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Single Cells as Biosensors for Chemical Separations by Shear, Jason B., Fishman, Harvey A., Allbritton, Nancy L., Garigan, Delia, Zare, Richard N., Scheller, Richard H.

“…A biosensor system based on the response of living cells was demonstrated that can detect specific components of a complex mixture fractionated by a…”
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A model neural interface based on functional chemical stimulation by Mehenti, Neville Z, Fishman, Harvey A, Bent, Stacey F

“…While functional electrical stimulation has been applied to treat a variety of neurological disorders, it cannot mimic function that is primarily achieved…”
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Controlling Cell Adhesion on Human Tissue by Soft Lithography by Lee, Christina J, Blumenkranz, Mark S, Fishman, Harvey A, Bent, Stacey F

“…Soft lithographic techniques are widely used for fundamental biological applications. This study investigates the extension of soft lithography for use on…”
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OCTAI: Smartphone-based Optical Coherence Tomography Image Analysis System by Rao, Adrit, Fishman, Harvey A.

“…Identifying diseases in Optical Coherence Tomography (OCT) images using Deep Learning models and methods is emerging as a powerful technique to enhance…”
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Ion Channels and Lipid Bilayer Membranes Under High Potentials Using Microfabricated Apertures by Peterman, Mark C, Ziebarth, Jonathan M, Braha, Orit, Bayley, Hagan, Fishman, Harvey A, Bloom, D M

“…Membrane-bound proteins are important from both a scientific and a technological point of view. However, their study and application require a stable lipid…”
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Directed Retinal Nerve Cell Growth for Use in a Retinal Prosthesis Interface by Leng, Theodore, Wu, Peggy, Mehenti, Neville Z, Bent, Stacey F, Marmor, Michael F, Blumenkranz, Mark S, Fishman, Harvey A

“…Retinal prosthetic devices that use microelectrode arrays to stimulate retinal nerve cells may provide a viable treatment for degenerative retinal diseases…”
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A model retinal interface based on directed neuronal growth for single cell stimulation by Mehenti, Neville Z, Tsien, Greg S, Leng, Theodore, Fishman, Harvey A, Bent, Stacey F

“…In this work, we use cell micropatterning technologies to direct neuronal growth to individual electrodes, and demonstrate that such an approach can achieve…”
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Use of 2,3-Naphthalenedicarboxaldehyde Derivatization for Single-Cell Analysis of Glutathione by Capillary Electrophoresis and Histochemical Localization by Fluorescence Microscopy by Orwar, Owe, Fishman, Harvey A, Ziv, Noam E, Scheller, Richard H, Zare, Richard N

“…We report that 2,3-naphthalenedicarboxaldehyde reacts rapidly with glutathione and its precursor, gamma-glutamylcysteine, to form highly fluorescent…”
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Chemomechanical Production of Submicron Edge Width, Functionalized, ∼20 μm Features on Silicon by Lua, Yit-Yian, Niederhauser, Travis L, Wacaser, Brent A, Mowat, Ian A, Woolley, Adam T, Davis, Robert C, Fishman, Harvey A, Linford, Matthew R

“…We recently reported that monolayers on silicon are formed, and silicon surfaces concomitantly patterned, when native oxide-coated silicon is scribed with a…”
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Fluid Flow Past an Aperture in a Microfluidic Channel by Peterman, Mark C, Noolandi, Jaan, Blumenkranz, Mark S, Fishman, Harvey A

“…Electroosmotically driven flow in neurotransmitter-based retinal prostheses offers a novel approach to interfacing the nervous system. Here, we show that…”
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Towards a Neurotransmitter-Based Retinal Prosthesis Using an Inkjet Print-head by Noolandi, Jaan, Peterman, Mark C, Huie, Philip, Lee, Christina, Blumenkranz, Mark S, Fishman, Harvey A

“…Electronic chips that provide a patterned stimulus to cells in the retina may provide a viable treatment for age-related macular degeneration. A surrogate MEMS…”
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Patch-Clamp Detection of Neurotransmitters in Capillary Electrophoresis by Orwar, Owe, Jardemark, Kent, Jacobson, Ingemar, Moscho, Alexander, Fishman, Harvey A., Scheller, Richard H., Zare, Richard N.

“…Gamma-aminobutyrate acid, L-glutamate, and N-methyl-D-aspartate were separated by capillary electrophoresis and detected by the use of whole-cell and…”
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