Search Results - "Fisher, S J"

The correlation between National Health Service trusts' clinical trial activity and both mortality rates and care quality commission ratings: a retrospective cross-sectional study by Jonker, L., Fisher, S.J.

“…Evidence supporting the notion that clinical research activity in itself is of benefit to organisations as a whole is inconclusive. In the recent past, a…”
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Molecular Classifiers for Acute Kidney Transplant Rejection in Peripheral Blood by Whole Genome Gene Expression Profiling by Kurian, S. M., Williams, A. N., Gelbart, T., Campbell, D., Mondala, T. S., Head, S. R., Horvath, S., Gaber, L., Thompson, R., Whisenant, T., Lin, W., Langfelder, P., Robison, E. H., Schaffer, R. L., Fisher, J. S., Friedewald, J., Flechner, S. M., Chan, L. K., Wiseman, A. C., Shidban, H., Mendez, R., Heilman, R., Abecassis, M. M., Marsh, C. L., Salomon, D. R.

“…There are no minimally invasive diagnostic metrics for acute kidney transplant rejection (AR), especially in the setting of the common confounding diagnosis,…”
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SynchWeb: a modern interface for ISPyB by Fisher, S. J., Levik, K. E., Williams, M. A., Ashton, A. W., McAuley, K. E.

“…SynchWeb is a modern interface to the ISPyB database. It significantly simplifies sample registration and is targeted towards live data collection monitoring…”
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Decidual Stromal Cell Response to Paracrine Signals from the Trophoblast: Amplification of Immune and Angiogenic Modulators by Hess, A P, Hamilton, A E, Talbi, S, Dosiou, C, Nyegaard, M, Nayak, N, Genbecev-Krtolica, O, Mavrogianis, P, Ferrer, K, Kruessel, J, Fazleabas, A T, Fisher, S J, Giudice, L C

“…During the invasive phase of implantation, trophoblasts and maternal decidual stromal cells secrete products that regulate trophoblast differentiation and…”
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Protonation-state determination in proteins using high-resolution X-ray crystallography: effects of resolution and completeness by Fisher, S. J., Blakeley, M. P., Cianci, M., McSweeney, S., Helliwell, J. R.

“…A bond‐distance analysis has been undertaken to determine the protonation states of ionizable amino acids in trypsin, subtilisin and lysozyme. The diffraction…”
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A genomics-based framework for identifying biomarkers of human neurodevelopmental toxicity by Robinson, J.F., Gormley, M.J., Fisher, S.J.

“…•Identified differentially expressed (DE) genes in hESC neurogenesis (n=5 studies, in vitro).•Described regulation of in vitro DE genes during human embryo…”
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Perdeuteration: improved visualization of solvent structure in neutron macromolecular crystallography by Fisher, S. J., Blakeley, M. P., Howard, E. I., Petit-Haertlein, I., Haertlein, M., Mitschler, A., Cousido-Siah, A., Salvay, A. G., Popov, A., Muller-Dieckmann, C., Petrova, T., Podjarny, A.

“…The 1.8 Å resolution neutron structure of deuterated type III antifreeze protein in which the methyl groups of leucine and valine residues are selectively…”
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The adverse effects of maternal smoking on the human placenta: A review by Zdravkovic, T., Genbacev, O., McMaster, M.T., Fisher, S.J.

“…Studies of placental pathologies associated with maternal cigarette smoking have led to many interesting observations. For example, maternal smoking impairs…”
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Human cytotrophoblast differentiation/invasion is abnormal in pre- eclampsia by Lim, KH, Zhou, Y, Janatpour, M, McMaster, M, Bass, K, Chun, SH, Fisher, SJ

“…During human placental development, cytotrophoblast stem cells differentiate and invade the uterus. Simultaneously, the cells modulate their expression of…”
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Preeclampsia Is Associated with Widespread Apoptosis of Placental Cytotrophoblasts within the Uterine Wall by DiFederico, Elaine, Genbacev, Olga, Fisher, Susan J.

“…Preeclampsia is a serious pregnancy complication diagnosed by signs of widespread maternal endothelial dysfunction. In normal pregnancy, a subpopulation of…”
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Expression of oestrogen receptor beta (ER beta) occurs in multiple cell types, including some germ cells, in the rat testis by Saunders, PT, Fisher, JS, Sharpe, RM, Millar, MR

“…The identification of a second oestrogen receptor (beta) has prompted a re-evaluation of the potential sites of action of oestrogens. The aim of the present…”
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Preeclampsia is associated with failure of human cytotrophoblasts to mimic a vascular adhesion phenotype. One cause of defective endovascular invasion in this syndrome? by Zhou, Y, Damsky, C H, Fisher, S J

“…In human pregnancy, placental cytotrophoblasts that invade the uterus downregulate the expression of adhesion receptors that are characteristic of their…”
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Regulation of Human Placental Development by Oxygen Tension by Genbacev, Olga, Zhou, Yan, Ludlow, John W., Fisher, Susan J.

“…Cytotrophoblasts, specialized placental cells, proliferate early in pregnancy and then differentiate into tumor-like cells that establish blood flow to the…”
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The glial cells missing-1 protein is essential for branching morphogenesis in the chorioallantoic placenta by Cross, James C, Anson-Cartwright, Lynn, Dawson, Kerri, Holmyard, Doug, Fisher, Susan J, Lazzarini, Robert A

“…Trophoblast cells of the placenta are established at the blastocyst stage and differentiate into specialized subtypes after implantation. In mice, the outer…”
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Human cytotrophoblasts adopt a vascular phenotype as they differentiate. A strategy for successful endovascular invasion? by Zhou, Y, Fisher, S J, Janatpour, M, Genbacev, O, Dejana, E, Wheelock, M, Damsky, C H

“…Establishment of the human placenta requires that fetal cytotrophoblast stem cells in anchoring chorionic villi become invasive. These cytotrophoblasts…”
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Interaction between shallow groundwater, saline surface water and contaminant discharge at a seasonally and tidally forced estuarine boundary by Westbrook, S.J., Rayner, J.L., Davis, G.B., Clement, T.P., Bjerg, P.L., Fisher, S.J.

“…This paper presents findings from a 2-year field investigation of a dissolved hydrocarbon groundwater plume flowing towards a tidally and seasonally forced…”
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Establishment of fetomaternal tolerance through glycan-mediated B cell suppression by Rizzuto, G., Brooks, J. F., Tuomivaara, S. T., McIntyre, T. I., Ma, S., Rideaux, D., Zikherman, J., Fisher, S. J., Erlebacher, A.

“…Discrimination of self from non-self is fundamental to a wide range of immunological processes 1 . During pregnancy, the mother does not recognize the placenta…”
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Detection of atherosclerosis using a novel positron-sensitive probe and 18-fluorodeoxyglucose (FDG) by LEDERMAN, R J, RAYLMAN, R R, FISHER, S J, KISON, P V, SAN, H, NABEL, E G, WAHL, R L

“…Inflammation contributes to atherosclerotic plaque remodeling, enlargement and rupture. Non-invasive imaging of coronary artery inflammation could help target…”
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Immunolocalisation of oestrogen receptor-alpha within the testis and excurrent ducts of the rat and marmoset monkey from perinatal life to adulthood by Fisher, J S, Millar, M R, Majdic, G, Saunders, P T, Fraser, H M, Sharpe, R M

“…The sites of action and the physiological role of oestrogens in the male reproductive tract are poorly understood. We have undertaken a systematic study of the…”
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Hair cycle and wound healing in mice with a keratinocyte-restricted deletion of FAK by ESSAYEM, S, KOVACIC-MILIVOJEVIC, B, FISHER, S. J, JORCANO, J. L, BEGGS, H. E, REICHARDT, L. F, ILIC, D, BAUMBUSCH, C, MCDONAGH, S, DOLGANOV, G, HOWERTON, K, LAROCQUE, N, MAURO, T, RAMIREZ, A, RAMOS, D. M

“…Focal adhesion kinase (FAK) is a critical component in transducing signals downstream of both integrins and growth factor receptors. To determine how the loss…”
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