Search Results - "Fisher, Matthew C"
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The WHO fungal priority pathogens list as a game-changer
Published in Nature reviews. Microbiology (01-04-2023)“…Invasive fungal diseases are on the increase globally. The World Health Organization fungal priority pathogens list highlights fungi of critical or high…”
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2
Worldwide emergence of resistance to antifungal drugs challenges human health and food security
Published in Science (American Association for the Advancement of Science) (18-05-2018)“…The recent rate of emergence of pathogenic fungi that are resistant to the limited number of commonly used antifungal agents is unprecedented. The azoles, for…”
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3
Tackling the emerging threat of antifungal resistance to human health
Published in Nature reviews. Microbiology (01-09-2022)“…Invasive fungal infections pose an important threat to public health and are an under-recognized component of antimicrobial resistance, an emerging crisis…”
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Virulence and Pathogenicity of Chytrid Fungi Causing Amphibian Extinctions
Published in Annual review of microbiology (08-10-2021)“…Ancient enzootic associations between wildlife and their infections allow evolution to innovate mechanisms of pathogenicity that are counterbalanced by host…”
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Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy
Published in Nature reviews. Neurology (01-01-2017)“…Key Points In most clinical centres in Africa, despite access to antiretroviral therapies, cases of HIV-associated cryptococcal meningitis (CM) are not…”
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Batrachochytrium salamandrivorans sp. nov. causes lethal chytridiomycosis in amphibians
Published in Proceedings of the National Academy of Sciences - PNAS (17-09-2013)“…The current biodiversity crisis encompasses a sixth mass extinction event affecting the entire class of amphibians. The infectious disease chytridiomycosis is…”
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Emerging fungal threats to animal, plant and ecosystem health
Published in Nature (London) (12-04-2012)“…Pathogenic fungi are increasingly contributing to the global emerging disease burden, threatening biodiversity and imposing increasing costs on ecosystem…”
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Threats Posed by the Fungal Kingdom to Humans, Wildlife, and Agriculture
Published in mBio (05-05-2020)“…The fungal kingdom includes at least 6 million eukaryotic species and is remarkable with respect to its profound impact on global health, biodiversity,…”
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First hospital outbreak of the globally emerging Candida auris in a European hospital
Published in Antimicrobial resistance & infection control (19-10-2016)“…is a globally emerging multidrug resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of in a London cardio-thoracic center…”
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10
Mitigating amphibian chytridiomycoses in nature
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05-12-2016)“…Amphibians across the planet face the threat of population decline and extirpation caused by the disease chytridiomycosis. Despite consensus that the fungal…”
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Amphibian chytridiomycosis outbreak dynamics are linked with host skin bacterial community structure
Published in Nature communications (15-02-2018)“…Host-associated microbes are vital for combatting infections and maintaining health. In amphibians, certain skin-associated bacteria inhibit the fungal…”
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The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis
Published in PLoS pathogens (01-05-2018)“…Fungal cells change shape in response to environmental stimuli, and these morphogenic transitions drive pathogenesis and niche adaptation. For example,…”
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13
Illuminating choices for library prep: a comparison of library preparation methods for whole genome sequencing of Cryptococcus neoformans using Illumina HiSeq
Published in PloS one (19-11-2014)“…The industry of next-generation sequencing is constantly evolving, with novel library preparation methods and new sequencing machines being released by the…”
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14
Mapping the global emergence of Batrachochytrium dendrobatidis, the amphibian chytrid fungus
Published in PloS one (27-02-2013)“…The rapid worldwide emergence of the amphibian pathogen Batrachochytrium dendrobatidis (Bd) is having a profound negative impact on biodiversity. However,…”
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15
Microscopic Aquatic Predators Strongly Affect Infection Dynamics of a Globally Emerged Pathogen
Published in Current biology (20-01-2014)“…Research on emerging infectious wildlife diseases has placed particular emphasis on host-derived barriers to infection and disease. This focus neglects…”
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The human fungal pathogen Aspergillus fumigatus can produce the highest known number of meiotic crossovers
Published in PLoS biology (14-09-2023)“…Sexual reproduction involving meiosis is essential in most eukaryotes. This produces offspring with novel genotypes, both by segregation of parental…”
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Genomic innovations linked to infection strategies across emerging pathogenic chytrid fungi
Published in Nature communications (21-03-2017)“…To understand the evolutionary pathways that lead to emerging infections of vertebrates, here we explore the genomic innovations that allow free-living chytrid…”
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18
Nonrandom Distribution of Azole Resistance across the Global Population of Aspergillus fumigatus
Published in mBio (21-05-2019)“…The emergence of azole resistance in the pathogenic fungus has continued to increase, with the dominant resistance mechanisms, consisting of a 34-nucleotide…”
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Elevated Corticosterone Levels and Changes in Amphibian Behavior Are Associated with Batrachochytrium dendrobatidis (Bd) Infection and Bd Lineage
Published in PloS one (20-04-2015)“…Few studies have examined the role hormones play in mediating clinical changes associated with infection by the parasite Batrachochytrium dendrobatidis (Bd)…”
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Successful elimination of a lethal wildlife infectious disease in nature
Published in Biology letters (2005) (01-11-2015)“…Methods to mitigate the impacts of emerging infectious diseases affecting wildlife are urgently needed to combat loss of biodiversity. However, the successful…”
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