Search Results - "Fisher, M. H."

Evaluation of a stranger safety training programme for adults with Williams syndrome by Fisher, M. H.

“…Background Individuals with Williams syndrome (WS) are reported to display increased sociability towards strangers, leading to increased social vulnerability…”
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Longitudinal trajectories of intellectual and adaptive functioning in adolescents and adults with Williams syndrome by Fisher, M. H., Lense, M. D., Dykens, E. M.

“…Background Williams syndrome (WS) is associated with a distinct cognitive‐behavioural phenotype including mild to moderate intellectual disability,…”
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Internet use and online safety in adults with Williams syndrome by Lough, E., Fisher, M. H.

“…Background Individuals with intellectual and developmental disabilities (IDD) increasingly have access to the Internet. Whilst Internet access increases…”
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Corticosterone alters materno‐fetal glucose partitioning and insulin signalling in pregnant mice by Vaughan, O. R., Fisher, H. M., Dionelis, K. N., Jefferies, E. C., Higgins, J. S., Musial, B., Sferruzzi‐Perri, A. N., Fowden, A. L.

“…Key points Glucocorticoids regulate fetal and adult glucose metabolism, in part by influencing the actions of insulin. However, their effects on materno‐fetal…”
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Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine by Aitken, R. John, Fisher, Helen M., Fulton, Norma, Gomez, Emilio, Knox, Wendy, Lewis, Beverley, Irvine, Stewart

“…Human spermatozoa possess a specialized capacity to generate reactive oxygen species (ROS) that is thought to be of significance in the redox regulation of…”
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Inhibition of expression of the multidrug resistance-associated P-glycoprotein of by phosphorothioate and 5' cholesterol-conjugated phosphorothioate antisense oligonucleotides by Alahari, S K, Dean, N M, Fisher, M H, Delong, R, Manoharan, M, Tivel, K L, Juliano, R L

“…Multiple drug resistance (MDR) as a result of overexpression of the P-glycoprotein drug transporter, a product of the MDR1 gene, is a significant problem in…”
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Cognitive problems following hematopoietic stem cell transplant: relationships with sleep, depression and fatigue by Ghazikhanian, S E, Dorfman, C S, Somers, T J, O'Sullivan, M L, Fisher, H M, Edmond, S N, Wren, A A, Kelleher, S A, Rowe Nichols, K A, Chao, N, Shelby, R A

“…Cognitive problems are a significant, persistent concern for patients undergoing hematopoietic stem cell transplant (HSCT). Sleep is important for many…”
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Eprinomectin: A novel avermectin for use as a topical endectocide for cattle by Shoop, W.L., Egerton, J.R., Eary, C.H., Haines, H.W., Michael, B.F., Mrozik, H., Eskola, P., Fisher, M.H., Slayton, L., Ostlind, D.A., Skelly, B.J., Fulton, R.K., Barth, D., Costa, S., Gregory, L.M., Campbell, W.C., Seward, R.L., Turner, M.J.

“…Eprinomectin (MK-397 or 4″-epi-acetylamino-4″-deoxy-avermectin B 1) is a novel avermectin selected for development as a topical endectocide for all cattle,…”
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Three-dimensional rendering of otolith growth using phase contrast synchrotron tomography by Mapp, J. J. I., Fisher, M. H., Atwood, R. C., Bell, G. D., Greco, M. K., Songer, S., Hunter, E.

“…A three‐dimensional computer reconstruction of a plaice Pleuronectes platessa otolith is presented from data acquired by the Diamond Light synchrotron,…”
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Identification and initial structure-activity relationships of a novel non-peptide quinolone GnRH receptor antagonist by DeVita, Robert J., Hollings, Darius D., Goulet, Mark T., Wyvratt, Matthew J., Fisher, Michael H., Lo, Jane-L., Yang, Yi Tien, Cheng, Kang, Smith, Roy G.

“…Screening of the Merck sample collection for non-peptide compounds with binding affinity for the rat GnRH receptor led to the identification of the substituted…”
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Efficacy in sheep and pharmacokinetics in cattle that led to the selection of eprinomectin as a topical endectocide for cattle by Shoop, W.L., Demontigny, P., Fink, D.W., Williams, J.B., Egerton, J.R., Mrozik, H., Fisher, M.H., Skelly, B.J., Turner, M.J.

“…Eprinomectin (MK-397 or 4″-epi-acetylamino-4″-deoxy-avermectin B 1) is a novel avermectin selected for development as a topical endectocide for all cattle,…”
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Phosphoinositide 3-kinase is involved in the induction of the human sperm acrosome reaction downstream of tyrosine phosphorylation by FISHER, H. M, BREWIS, I. A, BARRATT, C. L. R, COOKE, I. D, MOORE, H. D. M

“…In somatic cells phosphoinositide 3-kinase (PI 3-kinase) is activated upon interaction with both receptor tyrosine kinases (RTK) and G-proteins resulting in…”
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Ivermectin: a potent new antiparasitic agent [Nematode and arthropod parasites] by CAMPBELL, W. C, FISHER, M. H, STAPLEY, E. O, ALBERS-SCHONBERG, G, JACOB, T. A

“…Ivermectin is the 22,23-dihydro derivative of avermectin B$_{1}$, a macrocyclic lactone produced by an actinomycete, Streptomyces avermitilis. It is active at…”
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Synthesis of Apicidin-Derived Quinolone Derivatives:  Parasite-Selective Histone Deacetylase Inhibitors and Antiproliferative Agents by Meinke, Peter T, Colletti, Steven L, Doss, George, Myers, Robert W, Gurnett, Anne M, Dulski, Paula M, Darkin-Rattray, Sandra J, Allocco, John J, Galuska, Stefan, Schmatz, Dennis M, Wyvratt, Matthew J, Fisher, Michael H

“…Apicidin's indole was efficiently converted into a series of N-substituted quinolone derivatives by indole N-alkylation followed by a two-step, one-pot,…”
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Peptidomimetic Regulation of Growth Hormone Secretion by Smith, Roy G, Van der Ploeg, Lex H. T, Howard, Andrew D, Feighner, Scott D, Cheng, Kang, Hickey, Gerard J, Wyvratt, Matthew J, Fisher, Mike H, Nargund, Ravi P, Patchett, Arthur A

“…I. Introduction II. Identification of Peptidomimetic GH Secretagogues A. Mechanism of action of GHRH, GHRP-6, and somatostatin B. In vitro assays III…”
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Investigation of the 4-O-alkylamine substituent of non-peptide quinolone GnRH receptor antagonists by DeVita, Robert J., Goulet, Mark T., Wyvratt, Matthew J., Fisher, Michael H., Lo, Jane-L., Yang, Yi Tien, Cheng, Kang, Smith, Roy G.

“…Synthesis and in vitro activity of the enantiomers of quinolone GnRH antagonist (±)- 1 are reported. Chiral amino alcohols were prepared from the appropriate…”
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SYSTEMIC EFFICACY OF NODULISPORAMIDES AGAINST FLEAS ON DOGS by Shoop, W. L, Zakson-Aiken, M, Gregory, L. M, Michael, B. F, Pivnichny, J, Meinke, P. T, Fisher, M. H, Wyvratt, M. J, Pikounis, B, Schmatz, D. M

“…Nodulisporic acid A (NSA) has been shown previously to be safe in dogs and to deliver >90% flea control for 4 days following a single oral administration…”
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Stimulation of growth hormone release from rat primary pituitary cells by L-692,429, a novel non-peptidyl GH secretagogue by Cheng, K, Chan, W W, Butler, B, Wei, L, Schoen, W R, Wyvratt, Jr, M J, Fisher, M H, Smith, R G

“…L-692,429, a benzolactam derivative, stimulated GH release from rat primary pituitary cells in a dose-dependent manner. The concentration of L-692,429 required…”
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Potent antagonists of gonadotropin releasing hormone receptors derived from quinolone-6-carboxamides by Walsh, Thomas F, Toupence, Richard B, Young, Jonathan R, Huang, Song X, Ujjainwalla, Feroze, DeVita, Robert J, Goulet, Mark T, Wyvratt, Matthew J, Fisher, Michael H, Lo, Jane-Ling, Ren, Ning, Yudkovitz, Joel B, Yang, Yi Tien, Cheng, Kang, Smith, Roy G

“…SAR studies which focused upon the C-6 position of a recently described series of quinolone gonadotropin releasing hormone antagonists are reported. Synthetic…”
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Recent advances in avermectin research by Fisher, M. H.

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