Search Results - "Fisher, Larry W"

Surf4 (Erv29p) binds amino-terminal tripeptide motifs of soluble cargo proteins with different affinities, enabling prioritization of their exit from the endoplasmic reticulum by Yin, Ying, Garcia, Mekka R, Novak, Alexander J, Saunders, Allison M, Ank, Raira S, Nam, Anna S, Fisher, Larry W

“…Some secreted proteins that assemble into large complexes, such as extracellular matrices or hormones and enzymes in storage granules, must be kept at…”
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Modulation of canonical Wnt signaling by the extracellular matrix component biglycan by Berendsen, Agnes D, Fisher, Larry W, Kilts, Tina M, Owens, Rick T, Robey, Pamela G, Gutkind, J. Silvio, Young, Marian F

“…Although extracellular control of canonical Wnt signaling is crucial for tissue homeostasis, the role of the extracellular microenvironment in modulating this…”
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SHED: Stem Cells from Human Exfoliated Deciduous Teeth by Miura, Masako, Gronthos, Stan, Zhao, Mingrui, Lu, Bai, Fisher, Larry W., Robey, Pamela Gehron, Shi, Songtao

“…To isolate high-quality human postnatal stem cells from accessible resources is an important goal for stem-cell research. In this study we found that…”
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Secreted Frizzled-related protein-2 (sFRP2) augments canonical Wnt3a-induced signaling by von Marschall, Zofia, Fisher, Larry W.

“…► sFRP2 enhances the Wnt3a-induced β-catenin stabilization and its nuclear translocation. ► sFRP2 enhances LRP6 phosphorylation and Wnt3a/β-catenin…”
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WISP1/CCN4: a potential target for inhibiting prostate cancer growth and spread to bone by Ono, Mitsuaki, Inkson, Colette A, Sonn, Robert, Kilts, Tina M, de Castro, Luis F, Maeda, Azusa, Fisher, Larry W, Robey, Pamela G, Berendsen, Agnes D, Li, Li, McCartney-Francis, Nancy, Brown, Aaron C, Crawford, Nigel P S, Molinolo, Alfredo, Jain, Alka, Fedarko, Neal S, Young, Marian F

“…Prostate cancer (PC) is a leading cause of death in men however the factors that regulate its progression and eventual metastasis to bone remain unclear. Here…”
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Targeting osteopontin suppresses glioblastoma stem‐like cell character and tumorigenicity in vivo by Lamour, Virginie, Henry, Aurélie, Kroonen, Jérôme, Nokin, Marie‐Julie, von Marschall, Zofia, Fisher, Larry W., Chau, Tieu‐Lan, Chariot, Alain, Sanson, Marc, Delattre, Jean‐Yves, Turtoi, Andrei, Peulen, Olivier, Rogister, Bernard, Castronovo, Vincent, Bellahcène, Akeila

“…Osteopontin (OPN) is a secreted protein involved in most aspects of tumor progression and metastasis development. Elevated OPN expression has been reported in…”
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DMP1 and DSPP: evidence for duplication and convergent evolution of two SIBLING proteins by Fisher, Larry W

“…Since first being proposed as a tandem gene family in 2001, the relatedness of the 5 SIBLING proteins (BSP, DMP1, DSPP, MEPE, and SPP1/OPN) has predominantly…”
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Dentin Matrix Protein-1 Isoforms Promote Differential Cell Attachment and Migration by von Marschall, Zofia, Fisher, Larry W.

“…Dentin matrix protein-1 (DMP1), bone sialoprotein (BSP), and osteopontin (OPN) are three SIBLINGs (small integrin-binding ligand, N-linked glycoproteins)…”
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Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins by Fisher, Larry W, Fedarko, Neal S

“…Bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), dentin sialophosphoprotein (DSPP), enamelin (ENAM), matrix extracellular phosphoglycoprotein (MEPE),…”
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Molecular evolution of dentin phosphoprotein among toothed and toothless animals by McKnight, Dianalee A, Fisher, Larry W

“…Dentin sialophosphoprotein (DSPP) is the largest member of the SIBLING family and is the most abundant noncollagenous protein in dentin. DSPP is also expressed…”
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Elevated Serum Bone Sialoprotein and Osteopontin in Colon, Breast, Prostate, and Lung Cancer by FEDARKO, Neal S, JAIN, Alka, KARADAG, Abdullah, VAN EMAN, Matthew R, FISHER, Larry W

“…Purpose: Histological studies have shown that the two sialoproteins, bone sialoprotein (BSP) and osteopontin (OPN), are induced in multiple types of cancer. We…”
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The small leucine‐rich proteoglycan biglycan modulates BMP‐4‐induced osteoblast differentiation by Chen, Xiao-Dong, Fisher, Larry W., Robey, Pamela Gehron, Young, Marian F.

“…ABSTRACT Biglycan (bgn) is a small leucine‐rich proteoglycan enriched in extracellular matrices of skeletal tissues. Bgn‐deficient mice develop age‐related…”
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Rough endoplasmic reticulum trafficking errors by different classes of mutant dentin sialophosphoprotein (DSPP) cause dominant negative effects in both dentinogenesis imperfecta and dentin dysplasia by entrapping normal DSPP by von Marschall, Zofia, Mok, Seeun, Phillips, Matthew D, McKnight, Dianalee A, Fisher, Larry W

“…Families with nonsyndromic dentinogenesis imperfecta (DGI) and the milder, dentin dysplasia (DD), have mutations in one allele of the dentin…”
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SIBLING Expression Patterns in Duct Epithelia Reflect the Degree of Metabolic Activity by Ogbureke, Kalu U.E, Fisher, Larry W

“…The SIBLING (Small Integrin-Binding LIgand, N-linked Glycoprotein) family of secreted glycophosphoproteins includes bone sialoprotein (BSP), dentin matrix…”
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TM14 Is a New Member of the Fibulin Family (Fibulin-7) That Interacts with Extracellular Matrix Molecules and Is Active for Cell Binding by de Vega, Susana, Iwamoto, Tsutomu, Nakamura, Takashi, Hozumi, Kentaro, McKnight, Dianalee A., Fisher, Larry W., Fukumoto, Satoshi, Yamada, Yoshihiko

“…We identified a new extracellular protein, TM14, by differential hybridization using mouse tooth germ cDNA microarrays. TM14 cDNA encodes 440 amino acids…”
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Small Integrin Binding Ligand N-Linked Glycoprotein Gene Family Expression in Different Cancers by FISHER, Larry W, JAIN, Alka, TAYBACK, Matt, FEDARKO, Neal S

“…Purpose: Members of the small integrin binding ligand N -linked glycoprotein (SIBLING) gene family have the capacity to bind and modulate the activity of…”
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Two members of the SIBLING family of proteins, DSPP and BSP, may predict the transition of oral epithelial dysplasia to oral squamous cell carcinoma by Ogbureke, Kalu U. E., Abdelsayed, Rafik A., Kushner, Harvey, Li, Li, Fisher, Larry W.

“…BACKGROUND: Patients with oral premalignant lesions (OPL) present with oral squamous cell carcinomas (OSCC) at a much higher rate than the general population…”
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In Vitro Effects of Dentin Matrix Protein-1 on Hydroxyapatite Formation Provide Insights into in Vivo Functions by Tartaix, Philippe H, Doulaverakis, Marie, George, Anne, Fisher, Larry W, Butler, William T, Qin, Chunlin, Salih, Erdjan, Tan, Melin, Fujimoto, Yukiji, Spevak, Lyudmila, Boskey, Adele L

“…Dentin matrix protein-1 (DMP1) is a mineralized tissue matrix protein synthesized by osteoblasts, hypertrophic chondrocytes, and ameloblasts as well as…”
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Small Integrin-Binding Proteins as Serum Markers for Prostate Cancer Detection by JAIN, Alka, MCKNIGHT, Dianalee A, FISHER, Larry W, HUMPHREYS, Elizabeth B, MANGOLD, Leslie A, PARTIN, Alan W, FEDARKO, Neal S

“…Purpose: The small integrin-binding ligand N-linked glycoprotein (SIBLING) gene family includes bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), dentin…”
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Dentin matrix protein 1 enhances invasion potential of colon cancer cells by bridging matrix metalloproteinase-9 to integrins and CD44 by KARADAG, Abdullah, FEDARKO, Neal S, FISHER, Larry W

“…The up-regulation of various matrix metalloproteinases (MMP), certain cell receptors such as integrins and CD44, and the SIBLING family of integrin-binding…”
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