Search Results - "Fishelson, Zvi"

Complement C5b-9 and Cancer: Mechanisms of Cell Damage, Cancer Counteractions, and Approaches for Intervention by Fishelson, Zvi, Kirschfink, Michael

“…The interactions of cancer cells with components of the complement system are highly complex, leading to an outcome that is either favorable or detrimental to…”
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Astrocytes from old Alzheimer's disease mice are impaired in Aβ uptake and in neuroprotection by Iram, Tal, Trudler, Dorit, Kain, David, Kanner, Sivan, Galron, Ronit, Vassar, Robert, Barzilai, Ari, Blinder, Pablo, Fishelson, Zvi, Frenkel, Dan

“…Abstract In Alzheimer's disease (AD), astrocytes undergo morphological changes ranging from atrophy to hypertrophy, but the effect of such changes at the…”
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Cell-Penetrating Peptide-Based Delivery of Macromolecular Drugs: Development, Strategies, and Progress by Sun, Zhe, Huang, Jinhai, Fishelson, Zvi, Wang, Chenhui, Zhang, Sihe

“…Cell-penetrating peptides (CPPs), developed for more than 30 years, are still being extensively studied due to their excellent delivery performance. Compared…”
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Receptor-Interacting Protein Kinases 1 and 3, and Mixed Lineage Kinase Domain-Like Protein Are Activated by Sublytic Complement and Participate in Complement-Dependent Cytotoxicity by Lusthaus, Michal, Mazkereth, Niv, Donin, Natalie, Fishelson, Zvi

“…The complement system participates in the pathogenesis of many diseases. Complement activation produces several active protein complexes and peptides,…”
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Live Cell Imaging of Outward and Inward Vesiculation Induced by the Complement C5b-9 Complex by Moskovich, Oren, Fishelson, Zvi

“…Cells resist death induced by the complement membrane attack complex (MAC, C5b-9) by removal of the MAC from their surface by an outward and/or inward…”
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Circulating mortalin in blood and activation of the alternative complement pathway as risk indicators in COVID-19 infection by Avraham, Maya, Sinkovits, György, Hurler, Lisa, Prohászka, Zoltán, Fishelson, Zvi

“…Mortalin/GRP75 is a ubiquitous mitochondrial chaperone related to the cytosolic heat shock protein 70. It protects cells from various types of damages and from…”
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Mortalin/GRP75 Binds to Complement C9 and Plays a Role in Resistance to Complement-dependent Cytotoxicity by Saar Ray, Moran, Moskovich, Oren, Iosefson, Ohad, Fishelson, Zvi

“…Mortalin/GRP75, the mitochondrial heat shock protein 70, plays a role in cell protection from complement-dependent cytotoxicity (CDC). As shown here,…”
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Mortalin inhibitors sensitize K562 leukemia cells to complement‐dependent cytotoxicity by Pilzer, David, Saar, Moran, Koya, Keizo, Fishelson, Zvi

“…Mortalin, the mitochondrial hsp70, is a vital constitutively expressed heat shock protein. Its elevated expression has been correlated with malignant…”
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Caveolin-1 and Dynamin-2 Are Essential for Removal of the Complement C5b-9 Complex via Endocytosis by Moskovich, Oren, Herzog, Lee-Or, Ehrlich, Marcelo, Fishelson, Zvi

“…The complement system, an important element of both innate and adaptive immunity, is executing complement-dependent cytotoxicity (CDC) with its C5b-9 protein…”
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Mortalin/GRP75 promotes release of membrane vesicles from immune attacked cells and protection from complement-mediated lysis by Pilzer, David, Fishelson, Zvi

“…The membrane attack complex (MAC) of the complement system is causing membrane damage and cell death. For protection, cells have adopted several resistance…”
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Emission of membrane vesicles: roles in complement resistance, immunity and cancer by Pilzer, David, Gasser, Olivier, Moskovich, Oren, Schifferli, Jurg A, Fishelson, Zvi

“…Complement-mediated cell death is caused by C5b-9, the membrane attack complex (MAC) composed of the five complement proteins C5b, C6, C7, C8, and C9. Assembly…”
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Programmed Necrotic Cell Death Induced by Complement Involves a Bid-Dependent Pathway by Ziporen, Lea, Donin, Natalie, Shmushkovich, Taisia, Gross, Atan, Fishelson, Zvi

“…The membrane attack complex (MAC) of the complement system induces a necrotic-type cell death. Earlier findings suggested that Bcl-2 protects cells from…”
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Urochordate histoincompatible interactions activate vertebrate-like coagulation system components by Oren, Matan, Escande, Marie-line, Paz, Guy, Fishelson, Zvi, Rinkevich, Baruch

“…The colonial ascidian Botryllus schlosseri expresses a unique allorecognition system. When two histoincompatible Botryllus colonies come into direct contact,…”
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Inhibition of the Complement Membrane Attack Complex by Schistosoma mansoni Paramyosin by JIUSHENG DENG, GOLD, Daniel, LOVERDE, Philip T, FISHELSON, Zvi

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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‘Rejected’ vs. ‘rejecting’ transcriptomes in allogeneic challenged colonial urochordates by Oren, Matan, Paz, Guy, Douek, Jacob, Rosner, Amalia, Fishelson, Zvi, Goulet, Tamar L., Henckel, Kolja, Rinkevich, Baruch

“…In botryllid ascidians, allogeneic contacts between histoincompatible colonies lead to inflammatory rejection responses, which eventually separate the…”
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Cancer resistance to complement-dependent cytotoxicity (CDC): Problem-oriented research and development by Gancz, Dana, Fishelson, Zvi

“…The number of anti-cancer antibodies in therapy and in clinical trials is increasing gradually while their curative efficacy remains rather limited due to the…”
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Contribution of heat shock proteins to cell protection from complement-mediated lysis by Fishelson, Zvi, Hochman, Ilan, Greene, Lois E., Eisenberg, Evan

“…The possible participation of hsc70 and hsp70 in cellular protection from complement damage was studied. Human erythroleukemia K562 cells were pretreated with…”
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Complement nomenclature 2014 by Kemper, Claudia, Pangburn, Michael K, Fishelson, Zvi

“…The first update since 1981 of the nomenclature used in the field of complement has been completed by the Complement Nomenclature Committee established under…”
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Regulation of Complement-Dependent Cytotoxicity by MicroRNAs miR-200b, miR-200c, and miR-217 by Hillman, Yaron, Mazkereth, Niv, Farberov, Luba, Shomron, Noam, Fishelson, Zvi

“…The impact of microRNAs (miRNAs) known to regulate numerous biologic processes on complement-dependent cytotoxicity (CDC) was investigated in K562 cells. The…”
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A role for the NF-κB pathway in cell protection from complement-dependent cytotoxicity by Gancz, Dana, Lusthaus, Michal, Fishelson, Zvi

“…Nucleated cells are equipped with several mechanisms that support their resistance to complement-dependent cytotoxicity (CDC). The role of the NF-κB pathway in…”
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