Search Results - "Fishburn, C S"
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A Targeted Mutation of the D3 Dopamine Receptor Gene is Associated with Hyperactivity in Mice
Published in Proceedings of the National Academy of Sciences - PNAS (05-03-1996)“…While most effects of dopamine in the brain are mediated by the D1 and D2 receptor subtypes, other members of this G protein-coupled receptor family have…”
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2
A novel short isoform of the D3 dopamine receptor generated by alternative splicing in the third cytoplasmic loop
Published in The Journal of biological chemistry (15-03-1993)“…The mouse D3 dopamine receptor has been cloned from olfactory tubercle cDNA using polymerase chain reaction and has been found to exist in two alternatively…”
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3
In vitro translation of D2 dopamine receptors and their chimaeras: analysis by subtype-specific antibodies
Published in Biochemical and biophysical research communications (15-12-1994)“…We have developed a range of specific anti-peptide antibodies directed against the D2 and D3 dopamine receptors, and their alternatively spliced isoforms. To…”
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4
Synthesis and processing of D2 dopamine receptors
Published in Biochemistry (Easton) (17-08-1993)“…Dopamine receptors belong to a superfamily of neurotransmitter receptors that are functionally coupled to guanine nucleotide binding proteins. In this study,…”
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5
Adenylyl cyclase interaction with the D2 dopamine receptor family; differential coupling to Gi, Gz, and Gs
Published in Cellular and molecular neurobiology (01-10-1999)“…1. The D2-type dopamine receptors are thought to inhibit adenylyl cyclase (AC), via coupling to pertussis toxin (PTX)-sensitive G proteins of the Gi family. We…”
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6
Ethanol acts synergistically with a D2 dopamine agonist to cause translocation of protein kinase C
Published in Molecular pharmacology (01-01-2001)“…Ethanol and other drugs of abuse increase synaptic dopamine levels; however, little is known about how ethanol alters dopaminergic signaling. We have reported…”
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7
The effect of haloperidol on D2 dopamine receptor subtype mRNA levels in the brain
Published in FEBS letters (14-02-1994)“…Chronic neuroleptic treatment induces an increase in the density of D2 dopamine receptors in the striatum. The effect of prolonged administration of…”
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8
Structural organization of the murine D3 dopamine receptor gene
Published in Journal of neurochemistry (01-02-1995)“…We have cloned the gene encoding the murine D3 dopamine receptor and have analyzed its intron-exon structural organization, to gain a better understanding of…”
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9
Degradation of plasma proteins by the trypsin-like enzyme of Porphyromonas gingivalis and inhibition of protease activity by a serine protease inhibitor of human plasma
Published in Oral microbiology and immunology (01-08-1991)“…The interaction between Porphyromonas gingivalis culture supernatant and human serum was examined. Hydrolysis of the major serum proteins was thiol-dependent…”
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10
Differential Glycosylation and Intracellular Trafficking for the Long and Short Isoforms of the D2 Dopamine Receptor (∗)
Published in The Journal of biological chemistry (15-12-1995)“…The D2 dopamine receptor exists in two alternatively spliced isoforms, “long” and “short” (D2L and D2S), which differ by 29 amino acids in the third…”
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11
Localization of a peripheral membrane protein: Gbetagamma targets Galpha(Z)
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2000)“…To explore the relative roles of protein-binding partners vs. lipid modifications in controlling membrane targeting of a typical peripheral membrane protein,…”
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12
Localization of a peripheral membrane protein: G beta gamma targets G alpha sub(Z)
Published in Proceedings of the National Academy of Sciences - PNAS (01-02-2000)“…To explore the relative roles of protein-binding partners vs. lipid modifications in controlling membrane targeting of a typical peripheral membrane protein, G…”
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13
Human D3 dopamine receptor in the medulloblastoma TE671 cell line: cross‐talk between D1 and D3 receptors
Published in FEBS letters (13-11-1998)“…In search of a cell line in which the D3 dopamine receptor is expressed endogenously, we found that the neuron‐derived human medulloblastoma cell line TE671…”
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14
Gbetagamma and palmitate target newly synthesized Galphaz to the plasma membrane
Published in The Journal of biological chemistry (25-06-1999)“…The subcellular location of a signaling protein determines its ability to transmit messages accurately and efficiently. Three different lipid modifications…”
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15
Coupling of Dopamine Receptors to G Proteins: Studies With Chimeric D sub(2)/D sub(3) Dopamine Receptors
Published in Cellular and molecular neurobiology (01-02-2002)“…D sub(2) and D sub(3) dopamine receptors belong to the superfamily of G protein-coupled receptors; they share a high degree of homology and are structurally…”
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16
Differential glycosylation and intracellular trafficking for the long and short isoforms of the D sub(2) dopamine receptor
Published in The Journal of biological chemistry (01-01-1995)“…The D sub(2) dopamine receptor exists in two alternatively spliced isoforms, "long" and "short" (D sub(2L) and D sub(2S)), which differ by 29 amino acids in…”
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Molecular cloning and characterisation of the gene encoding the murine D sub(4) dopamine receptor
Published in FEBS letters (01-01-1995)“…The murine D sub(4) dopamine receptor was isolated from a murine genomic DNA library. The receptor's entire coding region was contained within a 6 kb EcoRI…”
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18
Molecular cloning and characterisation of the gene encoding the murine D4 dopamine receptor
Published in FEBS letters (20-03-1995)“…The murine D4 dopamine receptor was isolated from a murine genomic DNA library. The receptor's entire coding region was contained within a 6 kb EcoRI genomic…”
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19
Early expression of D3 dopamine receptors in murine embryonic development
Published in FEBS letters (04-03-1996)“…In order to determine whether the D2 and D3 dopamine receptors may have a role in prenatal development, we have studied the mRNA expression and distribution of…”
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Functional expression of the murine D2, D3 and D4 dopamine receptors in Xenopus laevis oocytes
Published in FEBS letters (29-12-1997)“…The different murine D2‐type dopamine receptors (D2L, D2S, D3L, D3S, and D4) were expressed in Xenopus laevis oocytes. The D2‐type receptors were all similarly…”
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