Search Results - "Fish, Kenneth"

Pathological Basis for Deficient Excitatory Drive to Cortical Parvalbumin Interneurons in Schizophrenia by Chung, Daniel W, Fish, Kenneth N, Lewis, David A

“…Objective:Deficient excitatory drive to parvalbumin-containing cortical interneurons is proposed as a key neural substrate for altered gamma oscillations and…”
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Reduced Labeling of Parvalbumin Neurons and Perineuronal Nets in the Dorsolateral Prefrontal Cortex of Subjects with Schizophrenia by Enwright, John F, Sanapala, Sowmya, Foglio, Aaron, Berry, Raissa, Fish, Kenneth N, Lewis, David A

“…Alterations in cortical parvalbumin (PV)-containing neurons, including a reduced density of detectable neurons and lower PV levels, have frequently been…”
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The Nature of Prefrontal Cortical GABA Neuron Alterations in Schizophrenia: Markedly Lower Somatostatin and Parvalbumin Gene Expression Without Missing Neurons by Dienel, Samuel J, Fish, Kenneth N, Lewis, David A

“…In schizophrenia, somatostatin (SST) and parvalbumin (PV) mRNA levels are lower in the dorsolateral prefrontal cortex (DLPFC), but it remains unclear whether…”
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Comorbidities, sequelae, blood biomarkers and their associated clinical outcomes in the Mount Sinai Health System COVID-19 patients by Brojakowska, Agnieszka, Eskandari, Abrisham, Bisserier, Malik, Bander, Jeffrey, Garikipati, Venkata Naga Srikanth, Hadri, Lahouaria, Goukassian, David A, Fish, Kenneth M

“…With the continuing rise of SARS-CoV2 infection globally and the emergence of various waves in different countries, understanding characteristics of…”
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Total Internal Reflection Fluorescence (TIRF) Microscopy by Fish, Kenneth N

“…Total internal reflection fluorescence (TIRF) microscopy (TIRFM) is an elegant optical technique that provides for the excitation of fluorophores in an…”
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Targeting prefrontal cortex GABAergic microcircuits for the treatment of alcohol use disorder by Fish, Kenneth N, Joffe, Max E

“…Developing novel treatments for alcohol use disorders (AUDs) is of paramount importance for improving patient outcomes and alleviating the suffering related to…”
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Scaling of smaller pyramidal neuron size and lower energy production in schizophrenia by Schoonover, Kirsten E., Miller, Nora E., Fish, Kenneth N., Lewis, David A.

“…Dorsolateral prefrontal cortex (DLPFC) dysfunction in schizophrenia appears to reflect alterations in layer 3 pyramidal neurons (L3PNs), including smaller cell…”
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Cortical Deficits of Glutamic Acid Decarboxylase 67 Expression in Schizophrenia: Clinical, Protein, and Cell Type-Specific Features by Curley, Allison A., Arion, Dominique, Volk, David W., Asafu-Adjei, Josephine K., Sampson, Allan R., Fish, Kenneth N., Lewis, David A.

“…Depression was associated with increased inflammation as measured by elevated levels of interleukin-6 and high-sensitivity C-reactive protein in patients with…”
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Markedly Lower Glutamic Acid Decarboxylase 67 Protein Levels in a Subset of Boutons in Schizophrenia by Rocco, Brad R, Lewis, David A, Fish, Kenneth N

“…Abstract Background Convergent findings indicate that cortical gamma-aminobutyric acid (GABA)ergic circuitry is altered in schizophrenia. Postmortem studies…”
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Terminal type-specific cannabinoid CB1 receptor alterations in patients with schizophrenia: A pilot study by Chou, Shinnyi, Fish, Kenneth N, Lewis, David A, Sweet, Robert A

“…Individuals with schizophrenia are at elevated genetic risks for comorbid cannabis use, and often experience exacerbations of cognitive and psychotic symptoms…”
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Total internal reflection fluorescence (TIRF) microscopy by Fish, Kenneth N

“…Total internal reflection fluorescence (TIRF) microscopy (TIRFM) is an elegant optical technique that provides for the excitation of fluorophores in an…”
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Selective Loss of Smaller Spines in Schizophrenia by MacDonald, Matthew L, Alhassan, Jamil, Newman, Jason T, Richard, Michelle, Gu, Hong, Kelly, Ryan M, Sampson, Alan R, Fish, Kenneth N, Penzes, Peter, Wills, Zachary P, Lewis, David A, Sweet, Robert A

“…Objective:Decreased density of dendritic spines in adult schizophrenia subjects has been hypothesized to result from increased pruning of excess synapses in…”
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Myocardial Delivery of Lipidoid Nanoparticle Carrying modRNA Induces Rapid and Transient Expression by Turnbull, Irene C, Eltoukhy, Ahmed A, Fish, Kenneth M, Nonnenmacher, Mathieu, Ishikawa, Kiyotake, Chen, Jiqiu, Hajjar, Roger J, Anderson, Daniel G, Costa, Kevin D

“…Nanoparticle-based delivery of nucleotides offers an alternative to viral vectors for gene therapy. We report highly efficient in vivo delivery of modified…”
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Developmental pruning of excitatory synaptic inputs to parvalbumin interneurons in monkey prefrontal cortex by Chung, Daniel W., Wills, Zachary P., Fish, Kenneth N., Lewis, David A.

“…Working memory requires efficient excitatory drive to parvalbumin-positive (PV) interneurons in the primate dorsolateral prefrontal cortex (DLPFC)…”
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Cell type specific cannabinoid CB1 receptor distribution across the human and non-human primate cortex by Chou, Shinnyi, Ranganath, Tejis, Fish, Kenneth N., Lewis, David A., Sweet, Robert A.

“…Alterations in cannabinoid CB1 receptor (CB1R) are implicated in various psychiatric disorders. CB1R participates in both depolarization induced suppression of…”
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Laminar-Specific Alterations in Calbindin-Positive Boutons in the Prefrontal Cortex of Subjects With Schizophrenia by Fish, Kenneth N., Rocco, Brad R., Wilson, James D., Lewis, David A.

“…Cognitive deficits in schizophrenia are associated with altered GABA (gamma-aminobutyric acid) neurotransmission in the prefrontal cortex (PFC). GABA…”
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GABA Neuron Alterations, Cortical Circuit Dysfunction and Cognitive Deficits in Schizophrenia by Gonzalez-Burgos, Guillermo, Fish, Kenneth N., Lewis, David A.

“…Schizophrenia is a brain disorder associated with cognitive deficits that severely affect the patients' capacity for daily functioning. Whereas our…”
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Distinct Properties of Layer 3 Pyramidal Neurons from Prefrontal and Parietal Areas of the Monkey Neocortex by González-Burgos, Guillermo, Miyamae, Takeaki, Krimer, Yosef, Gulchina, Yelena, Pafundo, Diego E, Krimer, Olga, Bazmi, Holly, Arion, Dominique, Enwright, John F, Fish, Kenneth N, Lewis, David A

“…In primates, working memory function depends on activity in a distributed network of cortical areas that display different patterns of delay task-related…”
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Step-by-step evaluation and treatment of shoulder dislocation by Parnes, Nata, Perrine, Jeff, Fish, Kenneth J

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Altered Parvalbumin Basket Cell Terminals in the Cortical Visuospatial Working Memory Network in Schizophrenia by Fish, Kenneth N., Rocco, Brad R., DeDionisio, Adam M., Dienel, Samuel J., Sweet, Robert A., Lewis, David A.

“…Visuospatial working memory (vsWM), which is commonly impaired in schizophrenia, involves information processing across the primary visual cortex, association…”
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