Search Results - "Fischer, Wolfgang H."

CREB coactivator CRTC2 links hepatic ER stress and fasting gluconeogenesis by Wang, Yiguo, Vera, Liliana, Fischer, Wolfgang H, Montminy, Marc

“…In fasted mammals, circulating pancreatic glucagon stimulates hepatic gluconeogenesis in part through the CREB regulated transcription coactivator 2 (CRTC2,…”
Get full text

A Hormone-Dependent Module Regulating Energy Balance by Wang, Biao, Moya, Noel, Niessen, Sherry, Hoover, Heather, Mihaylova, Maria M., Shaw, Reuben J., Yates, John R., Fischer, Wolfgang H., Thomas, John B., Montminy, Marc

“…Under fasting conditions, metazoans maintain energy balance by shifting from glucose to fat burning. In the fasted state, SIRT1 promotes catabolic gene…”
Get full text

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes by Wang, Yiguo, Li, Gang, Goode, Jason, Paz, Jose C., Ouyang, Kunfu, Screaton, Robert, Fischer, Wolfgang H., Chen, Ju, Tabas, Ira, Montminy, Marc

“…Interactions between cyclic AMP and calcium signalling pathways mediated by the inositol 1,4,5-trisphosphate receptor are shown to regulate hepatic…”
Get full text

The CD100 Receptor Interacts with Its Plexin B2 Ligand to Regulate Epidermal γδ T Cell Function by Witherden, Deborah A., Watanabe, Megumi, Garijo, Olivia, Rieder, Stephanie E., Sarkisyan, Gor, Cronin, Shane J.F., Verdino, Petra, Wilson, Ian A., Kumanogoh, Atsushi, Kikutani, Hitoshi, Teyton, Luc, Fischer, Wolfgang H., Havran, Wendy L.

“…γδ T cells respond rapidly to keratinocyte damage, providing essential contributions to the skin wound healing process. The molecular interactions regulating…”
Get full text

GRP78 and Cripto Form a Complex at the Cell Surface and Collaborate To Inhibit Transforming Growth Factor β Signaling and Enhance Cell Growth by Shani, Gidi, Fischer, Wolfgang H., Justice, Nicholas J., Kelber, Jonathan A., Vale, Wylie, Gray, Peter C.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Protein Disulfide Bond Formation in the Cytoplasm during Oxidative Stress by Cumming, Robert C, Andon, Nancy L, Haynes, Paul A, Park, Minkyu, Fischer, Wolfgang H, Schubert, David

“…The majority of disulfide-linked cytosolic proteins are thought to be enzymes that transiently form disulfide bonds while catalyzing oxidation-reduction…”
Get full text

FoxL2 and Smad3 Coordinately Regulate Follistatin Gene Transcription by Blount, Amy L., Schmidt, Karsten, Justice, Nicholas J., Vale, Wylie W., Fischer, Wolfgang H., Bilezikjian, Louise M.

“…Follistatin is a transcriptional target and a modulator of activin action. Through an autocrine/paracrine loop, activin controls follistatin levels and thus…”
Get full text

Autocrine/paracrine regulation of pituitary function by activin, inhibin and follistatin by Bilezikjian, Louise M., Blount, Amy L., Leal, Angela M.O., Donaldson, Cindy J., Fischer, Wolfgang H., Vale, Wylie W.

“…The precise regulation of the anterior pituitary is achieved by the cell-specific and combined actions of central, peripheral and local factors. Activins,…”
Get full text

Neural cells secrete a unique repertoire of proteins by Schubert, David, Herrera, Federico, Cumming, Robert, Read, Jessica, Low, William, Maher, Pamela, Fischer, Wolfgang H

“…Proteins that are released from cells consist of those in the extracellular matrix, as well as extracellular signaling and adhesion molecules. The majority of…”
Get full text

An Activin Mutant with Disrupted ALK4 Binding Blocks Signaling via Type II Receptors by Harrison, Craig A, Gray, Peter C, Fischer, Wolfgang H, Donaldson, Cindy, Choe, Senyon, Vale, Wylie

“…Activins control many physiologic and pathophysiologic processes in multiple tissues and, like other TGF-β superfamily members, signal via type II…”
Get full text

Activin A/Bone Morphogenetic Protein (BMP) Chimeras Exhibit BMP-like Activity and Antagonize Activin and Myostatin by Korupolu, Radhika V., Muenster, Uwe, Read, Jessica D., Vale, Wylie, Fischer, Wolfgang H.

“…Activins and bone morphogenetic proteins (BMPs) are members of the transforming growth factor-β family of growth and differentiation factors that induce…”
Get full text

Junctional Adhesion Molecule JAML Is a Costimulatory Receptor for Epithelial γδ T Cell Activation by Witherden, Deborah A, Verdino, Petra, Rieder, Stephanie E, Garijo, Olivia, Mills, Robyn E, Teyton, Luc, Fischer, Wolfgang H, Wilson, Ian A, Havran, Wendy L

“…γδ T cells present in epithelial tissues provide a crucial first line of defense against environmental insults, including infection, trauma, and malignancy,…”
Get full text

Distinct Structural and Functional Roles of Conserved Residues in the First Extracellular Domain of Receptors for Corticotropin-releasing Factor and Related G-protein-coupled Receptors by Perrin, Marilyn H., Grace, Christy R.R., DiGruccio, Michael R., Fischer, Wolfgang H., Maji, Samir K., Cantle, Jeffrey P., Smith, Sean, Manning, Gerard, Vale, Wylie W., Riek, Roland

“…The G-protein-coupled receptor B1 family includes corticotropin-releasing factor (CRF), growth hormone-releasing hormone, incretin, and pituitary adenylate…”
Get full text

Three Forms of Gonadotropin-Releasing Hormone, Including a Novel Form, in a Basal Salmonid, Coregonus clupeaformis by ADAMS, Bruce A, VICKERS, Elaine D, WARBY, Carol, PARK, Minkyu, FISCHER, Wolfgang H, CRAIG, A. Grey, RIVIER, Jean E, SHERWOOD, Nancy M

“…Multiple forms of GnRH within individual brains may have different functions. However, some vertebrates such as salmonids continue to reproduce even though…”
Get full text

Assembly of Proteins to Postsynaptic Densities after Transient Cerebral Ischemia by Hu, Bing-Ren, Park, Minkyu, Martone, Maryann E, Fischer, Wolfgang H, Ellisman, Mark H, Zivin, Justin A

“…Transient ischemia leads to changes in synaptic efficacy and results in selective neuronal damage during the postischemic phase, although the mechanisms are…”
Get full text

An Activin-A/C Chimera Exhibits Activin and Myostatin Antagonistic Properties by Muenster, Uwe, Harrison, Craig A., Donaldson, Cynthia, Vale, Wylie, Fischer, Wolfgang H.

“…Activins are involved in many physiological and pathological processes and, like other members of the transforming growth factor-β superfamily, signal via type…”
Get full text

A Cellular Cofactor for the Constitutive Transport Element of Type D Retrovirus by Tang, Hengli, Gaietta, Guido M., Fischer, Wolfgang H., Ellisman, Mark H., Wong-Staal, Flossie

“…A human nuclear protein that specifically interacts with the constitutive transport element (CTE) of simian retrovirus was identified as adenosine…”
Get full text

Increase in Expression Levels and Resistance to Sulfhydryl Oxidation of Peroxiredoxin Isoforms in Amyloid β-Resistant Nerve Cells by Cumming, Robert C., Dargusch, Richard, Fischer, Wolfgang H., Schubert, David

“…Peroxiredoxins (Prxs) are a ubiquitously expressed family of thiol peroxidases that reduce hydrogen peroxide, peroxynitrite, and hydroperoxides using a highly…”
Get full text

Primary Structure of a Novel Gonadotropin-Releasing Hormone in the Brain of a Teleost, Pejerrey by Montaner, Alejandro D., Park, Min Kyu, Fischer, Wolfgang H., Craig, Anthony G., Chang, John P., Somoza, Gustavo M., Rivier, Jean E., Sherwood, Nancy M.

“…Abstract The neuropeptide GnRH is the major regulator of reproduction in vertebrates acting as a first signal from the hypothalamus to pituitary gonadotropes…”
Get full text

A cluster of phosphorylation sites on the cyclic AMP-regulated nuclear factor CREB predicted by its sequence by Gonzalez, Gustavo A, Yamamoto, Karen K, Fischer, Wolfgang H, Karr, David, Menzel, Patricia, Biggs III, William, Vale, Wylie W, Montminy, Marc R

“…Cyclic AMP regulates the expression of a number of genes through a conserved promoter element, the CRE1. Moreover, transcriptional induction by cAMP requires…”
Get full text