Search Results - "Fischer, WH"

Chemoimmunotherapy for melanoma with dacarbazine and 2,4-dinitrochlorobenzene elicits a specific T cell-dependent immune response by WACK, Christiane, KIRST, Annette, BECKER, Jürgen C, LUTZ, Werner K, BRÖCKER, Eva-B, FISCHER, Wolfgang H

“…An empirically established chemoimmunotherapy for metastatic melanoma combines the systemic administration of the chemotherapeutic agent dacarbazine (DTIC)…”
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Protein Disulfide Bond Formation in the Cytoplasm during Oxidative Stress by Cumming, Robert C, Andon, Nancy L, Haynes, Paul A, Park, Minkyu, Fischer, Wolfgang H, Schubert, David

“…The majority of disulfide-linked cytosolic proteins are thought to be enzymes that transiently form disulfide bonds while catalyzing oxidation-reduction…”
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Evidence that gonadotropin-releasing hormone (GnRH) functions as a prolactin-releasing factor in a teleost fish (Oreochromis mossambicus) and primary structures for three native GnRH molecules by Weber, GM, Powell, JF, Park, M, Fischer, WH, Craig, AG, Rivier, JE, Nanakorn, U, Parhar, IS, Ngamvongchon, S, Grau, EG, Sherwood, NM

“…Three forms of gonadotropin-releasing hormone (GnRH) are isolated and identified here by chemical sequence analysis for one species of tilapia, Oreochromis…”
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A Novel CDK9-Associated C-Type Cyclin Interacts Directly with HIV-1 Tat and Mediates Its High-Affinity, Loop-Specific Binding to TAR RNA by Wei, Ping, Garber, Mitchell E, Fang, Shi-Min, Fischer, Wolfgang H, Jones, Katherine A

“…The HIV-1 Tat protein regulates transcription elongation through binding to the viral TAR RNA stem-loop structure. We have isolated a novel 87 kDa cyclin…”
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Residues in the C-terminal region of activin A determine specificity for follistatin and type II receptor binding by Fischer, WH, Park, M, Donaldson, C, Wiater, E, Vaughan, J, Bilezikjian, LM, Vale, W

“…Activin is a secreted growth factor that signals by binding two related classes of single transmembrane receptors at the cell surface. The interaction of…”
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FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor by Taupin, P, Ray, J, Fischer, W H, Suhr, S T, Hakansson, K, Grubb, A, Gage, F H

“…We have purified and characterized a factor, from the conditioned medium of neural stem cell cultures, which is required for fibroblast growth factor 2's…”
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A Flexible Activin Explains the Membrane-Dependent Cooperative Assembly of TGF-β Family Receptors by Greenwald, Jason, Vega, Mark E, Allendorph, George P, Fischer, Wolfgang H, Vale, Wylie, Choe, Senyon

“…A new crystal structure of activin in complex with the extracellular domain of its type II receptor (ActRIIb-ECD) shows that the ligand exhibits an unexpected…”
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Autocrine/paracrine regulation of pituitary function by activin, inhibin and follistatin by Bilezikjian, Louise M., Blount, Amy L., Leal, Angela M.O., Donaldson, Cindy J., Fischer, Wolfgang H., Vale, Wylie W.

“…The precise regulation of the anterior pituitary is achieved by the cell-specific and combined actions of central, peripheral and local factors. Activins,…”
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Novel Vertebrate Nucleoporins Nup133 and Nup160 Play a Role in mRNA Export by Vasu, Sanjay, Shah, Sundeep, Orjalo, Arturo, Park, Minkyu, Fischer, Wolfgang H., Forbes, Douglass J.

“…RNA undergoing nuclear export first encounters the basket of the nuclear pore. Two basket proteins, Nup98 and Nup153, are essential for mRNA export, but their…”
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F‐spondin promotes nerve precursor differentiation by Schubert, David, Klar, Avihu, Park, Minkyu, Dargusch, Richard, Fischer, Wolfgang H.

“…Cells in the developing nervous system secrete a large number of proteins that regulate the migration and differentiation of their neighbors. It is shown here…”
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An Activin Mutant with Disrupted ALK4 Binding Blocks Signaling via Type II Receptors by Harrison, Craig A, Gray, Peter C, Fischer, Wolfgang H, Donaldson, Cindy, Choe, Senyon, Vale, Wylie

“…Activins control many physiologic and pathophysiologic processes in multiple tissues and, like other TGF-β superfamily members, signal via type II…”
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Regulation of B cell functions by C3a and C3a(desArg): suppression of TNF-alpha, IL-6, and the polyclonal immune response by Fischer, WH, Hugli, TE

“…Regulation of the humoral immune response by fragments of complement component C3 has been shown to play an important role in host defense. In this study, we…”
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Styelin D, an Extensively Modified Antimicrobial Peptide from Ascidian Hemocytes by Taylor, S W, Craig, A G, Fischer, W H, Park, M, Lehrer, R I

“…We isolated styelin D, a 32-residue, C-terminally amidated antimicrobial peptide, from the blood cells (hemocytes) of the solitary ascidian, Styela clava …”
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TGF‐beta superfamily members promote survival of midbrain dopaminergic neurons and protect them against MPP+ toxicity by Krieglstein, K., Suter‐Crazzolara, C., Fischer, W.H., Unsicker, K.

“…The superfamily of transforming growth factors‐beta (TGF‐beta) comprises an expanding list of multifunctional proteins serving as regulators of cell…”
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Primary structure and function of three gonadotropin-releasing hormones, including a novel form, from an ancient teleost, herring by Carolsfeld, J, Powell, J F, Park, M, Fischer, W H, Craig, A G, Chang, J P, Rivier, J E, Sherwood, N M

“…The evolution of GnRH and the role of multiple forms within the brain are examined. Three forms of GnRH were purified from the brain of Pacific herring (Clupea…”
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A Soluble Form of the First Extracellular Domain of Mouse Type 2β Corticotropin-releasing Factor Receptor Reveals Differential Ligand Specificity by Perrin, Marilyn H., DiGruccio, Michael R., Koerber, Steven C., Rivier, Jean E., Kunitake, Koichi S., Bain, Deborah L., Fischer, Wolfgang H., Vale, Wylie W.

“…The heptahelical receptors for corticotropin-releasing factor (CRF), CRFR1 and CRFR2, display different specificities for CRF family ligands: CRF and urocortin…”
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Regulation of IL-6 synthesis in human peripheral blood mononuclear cells by C3a and C3a(desArg) by Fischer, W H, Jagels, M A, Hugli, T E

“…The anaphylatoxin C3a has been reported to have immunomodulatory effects on a number of different cell types. In this study we investigated the effects of C3a…”
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Three Forms of Gonadotropin-Releasing Hormone, Including a Novel Form, in a Basal Salmonid, Coregonus clupeaformis by ADAMS, Bruce A, VICKERS, Elaine D, WARBY, Carol, PARK, Minkyu, FISCHER, Wolfgang H, CRAIG, A. Grey, RIVIER, Jean E, SHERWOOD, Nancy M

“…Multiple forms of GnRH within individual brains may have different functions. However, some vertebrates such as salmonids continue to reproduce even though…”
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Regulation of the ERBB-2 Promoter by RBPJκ and NOTCH by Chen, Yanyun, Fischer, Wolfgang H., Gill, Gordon N.

“…Within the human ERBB-2 gene promoter, a 100-base pair region 5′ to the TATA box enhances basal transcription 200-fold. Two palindromes present within this…”
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Assembly of Proteins to Postsynaptic Densities after Transient Cerebral Ischemia by Hu, Bing-Ren, Park, Minkyu, Martone, Maryann E, Fischer, Wolfgang H, Ellisman, Mark H, Zivin, Justin A

“…Transient ischemia leads to changes in synaptic efficacy and results in selective neuronal damage during the postischemic phase, although the mechanisms are…”
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