Search Results - "Fischer, T H"

Environmental Tobacco Smoke, Cardiovascular Disease, and the Nonlinear Dose-Response Hypothesis by Smith, Carr J., Fischer, Thomas H., Sears, Stephen B.

“…Two recent government reports have focused attention on the hypothesis that environmental tobacco smoke (ETS) exposure increases the risk of cardiovascular…”
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Particulate and vapor phase constituents of cigarette mainstream smoke and risk of myocardial infarction by Smith, Carr J, Fischer, Thomas H

“…On pharmacological and compositional grounds, cigarette mainstream smoke (MS) aerosol can be broadly categorized as consisting of the following constituents:…”
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Incorporation of Rap 1b into the platelet cytoskeleton is dependent on thrombin activation and extracellular calcium by T H Fischer, M N Gatling, F McCormick, C M Duffy, G C White, 2nd

“…Rap 1b is a 22-kDa low molecular mass GTP-binding protein which is both a member of the Ras superfamily and a substrate for cAMP-dependent protein kinase…”
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New haemostatic textile stopped refractory bleeding in an aplastic anaemia patient by SCHUMACHER, S. A., FISCHER, T. H., SMITH, C. J.

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Thrombolamban, the 22-KDa Platelet Substrate of Cyclic AMP-Dependent Protein Kinase, is Immunologically Homologous with the Ras Family of GTP-Binding Proteins by White, Thomas E., Lacal, Juan-Carlos, Reep, Bryan, Fischer, Thomas H., Lapetina, Eduardo G., White, Gilbert C.

“…Platelet inhibition by agents that increase intracellular levels of cAMP is associated with cAMP-dependent phosphorylation of specific intracellular proteins,…”
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Community engagement for pandemic preparedness and response in Sub-Saharan Africa: A Scoping Review by Razak, G, Fischer, H T, Appiah-Brimpong, E, Opoku, D, Hanefeld, J

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Cytoskeletal interactions of Rap1b in platelets by White, 2nd, G C, Crawford, N, Fischer, T H

“…We have presented evidence that rap1b, a 22 kDa low molecular weight GTP binding protein, becomes associated with the cytoskeleton in thrombin-activated…”
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Partial purification and characterization of thrombolamban, a 22,000 dalton cAMP-dependent protein kinase substrate in platelets by Fischer, T H, White, 2nd, G C

“…In preparations of human platelet microsomes, cyclic AMP-dependent protein kinase induced the rapid phosphorylation of a single protein that was…”
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rap1B, a cAMP-dependent protein kinase substrate, associates with the platelet cytoskeleton by Fischer, T H, Gatling, M N, Lacal, J C, White, G C

“…rap1B is a member of the ras superfamily of low molecular weight GTP binding proteins which constitutes a focal point of GTP and cAMP signal transduction…”
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The effect of Na+ and K+ on the thermal denaturation of Na+ and + K+-dependent ATPase by Fischer, T H

“…To increase our understanding of the physical nature of the Na+ and K+ forms of the Na+ + K+-dependent ATPase, thermal-denaturation studies were conducted in…”
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P981Predictor factors and the prognostic role of persistent pulmonary veins isolation in patients with arrhythmia recurrence necessitating a second ablation procedure by Vevecka, A, Schwab, C, Forkmann, M, Fischer, T H, Butz, S, Tuschner, O, Mahnkopf, C H, Brachmann, J, Busch, S

“…Abstract Aims Pulmonary vein isolation (PVI) is the treatment of choice in patients (pts) with symptomatic atrial fibrillation. Durable pulmonary veins…”
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4967Effects of atrial fibrillation on the human ventricle by Pabel, S, Ahmad, S, Knierim, M, Herting, J, Hollemann, D, Streckfuss-Boemeke, K, Brochhausen, C, Fischer, T H, Hasenfuss, G, Maier, L S, Sossalla, S

“…Abstract Background The consequence of normofrequent atrial fibrillation (AF) on the ventricle remains largely unknown. Methods and results To elucidate the…”
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An investigation of functional similarities between the sarcoplasmic reticulum and platelet calcium-dependent adenosinetriphosphatases with the inhibitors quercetin and calmidazolium by Fischer, Thomas H, Campbell, Kevin P, White, Gilbert C

“…The platelet and skeletal sarcoplasmic reticulum calcium-dependent adenosinetriphosphatases (Ca2+-ATPases) were functionally compared with respect to substrate…”
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cAMP-dependent protein kinase substrates in platelets. Evidence that thrombolamban, a 22,000 dalton substrate, and the Ca++-ATPase are not associated proteins by Fischer, T H, White, 2nd, G C

“…Inhibition of platelet function by cAMP is due at least in part to a reduction in the agonist stimulated increase in cytoplasmic calcium during cell…”
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P5703Selective activation of cardiac protein phosphatase 1 is of antiarrhythmic potential in human diseased myocardium by Eiringhaus, J, Fischer, T H, Dybkova, N, Saadatmand, A, Pabel, S, Weber, S, Wang, Y, Koehn, M, El-Armouche, A, Maier, L S, Hasenfuss, G, Sossalla, S

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The development of a high-order Taylor expansion solution to the chemical rate equation for the simulation of complex biochemical systems by Fischer, Thomas H., White, Gilbert C.

“…A numerical method for evaluating chemical rate equations is presented. This method was developed by expressing the system of coupled, first-degree, ordinary…”
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Cyclic AMP-dependent protein kinase does not increase calcium transport in platelet microsomes by White, 2nd, G C, Barton, D W, White, T E, Fischer, T H

“…Cyclic AMP inhibits platelet activation, at least in part, by reducing intracellular levels of ionic calcium. Previous studies using platelet microsomal…”
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Intracellular function in rehydrated lyophilized platelets by FISCHER, Thomas H, MERRICKS, Elizabeth P, RUSSELL, Karen E, RAYMER, Robin A, WHITE, Gilbert C, BODE, Arthur P, NICHOLS, Timothy C, READ, Marjorie S

“…This study aimed to evaluate the effect of cross-linking and lyophilization on intracellular signalling processes in rehydrated, lyophilized (RL) platelets,…”
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Urinary thromboxane, prostacyclin, cortisol, and 8-hydroxy-2'-deoxyguanosine in nonsmokers exposed and not exposed to environmental tobacco smoke by SMITH, Carr J, FISCHER, Thomas H, HEAVNER, David L, RUMPLE, Melissa A, BOWMAN, Denise L, BROWN, Buddy G, MORTON, Michael J, DOOLITTLE, David J

“…This study tested the hypotheses that (1) increased platelet aggregation, as measured by 2,3-dinor-thromboxane B(2) (Tx-M) and 2,3-dinor-6-keto-prostaglandin…”
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Imaging and Elastometry of Blood Clots Using Magnetomotive Optical Coherence Tomography and Labeled Platelets by Oldenburg, A. L., Gongting Wu, Spivak, D., Tsui, F., Wolberg, A. S., Fischer, T. H.

“…Improved methods for imaging and assessment of vascular defects are needed for directing treatment of cardiovascular pathologies. In this paper, we employ…”
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