Search Results - "Fischer, Stuart G."

ZNF70, a novel ILDR2-interacting protein, contributes to the regulation of HES1 gene expression by Watanabe, Kazuhisa, Nakayama, Kazuhiro, Ohta, Satoshi, Tago, Kenji, Boonvisut, Supichaya, Millings, Elizabeth J., Fischer, Stuart G., LeDuc, Charles A., Leibel, Rudolph L., Iwamoto, Sadahiko

“…A diabetes susceptibility gene, immunoglobulin-like domain containing receptor 2 (Ildr2), encodes a transmembrane protein localized to the endoplasmic…”
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ILDR2 has a negligible role in hepatic steatosis by Millings, Elizabeth J, De Rosa, Maria Caterina, Fleet, Sarah, Watanabe, Kazuhisa, Rausch, Richard, Egli, Dieter, Li, Gen, Leduc, Charles A, Zhang, Yiying, Fischer, Stuart G, Leibel, Rudolph L

“…We have previously reported that Ildr2 knockdown via adenovirally-delivered shRNA causes hepatic steatosis in mice. In the present study we investigated…”
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ILDR2: an endoplasmic reticulum resident molecule mediating hepatic lipid homeostasis by Watanabe, Kazuhisa, Watson, Elizabeth, Cremona, Maria Laura, Millings, Elizabeth J, Lefkowitch, Jay H, Fischer, Stuart G, LeDuc, Charles A, Leibel, Rudolph L

“…Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of…”
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Absence epilepsy in apathetic , a spontaneous mutant mouse lacking the h channel subunit, HCN2 by Chung, Wendy K, Shin, Minyoung, Jaramillo, Thomas C, Leibel, Rudolph L, LeDuc, Charles A, Fischer, Stuart G, Tzilianos, Efthia, Gheith, Ayman A, Lewis, Alan S, Chetkovich, Dane M

“…Abstract Analysis of naturally occurring mutations that cause seizures in rodents has advanced understanding of the molecular mechanisms underlying epilepsy…”
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Positional cloning of "Lisch-Like", a candidate modifier of susceptibility to type 2 diabetes in mice by Dokmanovic-Chouinard, Marija, Chung, Wendy K, Chevre, Jean-Claude, Watson, Elizabeth, Yonan, Jason, Wiegand, Beebe, Bromberg, Yana, Wakae, Nao, Wright, Chris V, Overton, John, Ghosh, Sujoy, Sathe, Ganesh M, Ammala, Carina E, Brown, Kathleen K, Ito, Rokuro, LeDuc, Charles, Solomon, Keely, Fischer, Stuart G, Leibel, Rudolph L

“…In 404 Lep(ob/ob) F2 progeny of a C57BL/6J (B6) x DBA/2J (DBA) intercross, we mapped a DBA-related quantitative trait locus (QTL) to distal Chr1 at 169.6 Mb,…”
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The Genomic Sequence of the Accidental Pathogen Legionella pneumophila by Chien, Minchen, Morozova, Irina, Shi, Shundi, Sheng, Huitao, Chen, Jing, Gomez, Shawn M., Asamani, Gifty, Hill, Kendra, Nuara, John, Feder, Marc, Rineer, Justin, Greenberg, Joseph J., Steshenko, Valeria, Park, Samantha H., Zhao, Baohui, Teplitskaya, Elita, Edwards, John R., Pampou, Sergey, Georghiou, Anthi, I. -Chun Chou, Iannuccilli, William, Ulz, Michael E., Kim, Dae H., Geringer-Sameth, Alex, Goldsberry, Curtis, Morozov, Pavel, Fischer, Stuart G., Segal, Gil, Qu, Xiaoyan, Rzhetsky, Andrey, Zhang, Peisen, Cayanis, Eftihia, De Jong, Pieter J., Ju, Jingyue, Kalachikov, Sergey, Shuman, Howard A., Russo, James J.

“…We present the genomic sequence of Legionella pneumophila, the bacterial agent of Legionnaires' disease, a potentially fatal pneumonia acquired from…”
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Familial Primary Pulmonary Hypertension (Gene PPH1) Is Caused by Mutations in the Bone Morphogenetic Protein Receptor–II Gene by Deng, Zemin, Morse, Jane H., Slager, Susan L., Cuervo, Nieves, Moore, Keith J., Venetos, George, Kalachikov, Sergey, Cayanis, Eftihia, Fischer, Stuart G., Barst, Robyn J., Hodge, Susan E., Knowles, James A.

“…Familial primary pulmonary hypertension is a rare autosomal dominant disorder that has reduced penetrance and that has been mapped to a 3-cM region on…”
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Load-Controlled Compression of Articular Cartilage Induces a Transient Stimulation of Aggrecan Gene Expression by Valhmu, Wilmot B., Stazzone, Enrico J., Bachrach, Nathaniel M., Saed-Nejad, Fatemeh, Fischer, Stuart G., Mow, Van C., Ratcliffe, Anthony

“…The effects of short- and long-term load-controlled compression on the levels of aggrecan mRNA have been determined. Results show that a compressive stress of…”
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An algorithm based on graph theory for the assembly of contigs in physical mapping of DNA by Zhang, Peisen, Schon, Eric A., Fischer, Stuart G., Cayanis, Eftihia, Weiss, Janie, Kistler, Susan, Bourne, Philip E.

“…An algorithm is described for mapping DNA contigs based on an interval graph (IG) representation. In general terms, the input to the algorithm is a set of…”
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Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis by Myers, Richard M., Fischer, Stuart G., Maniatis, Tom, Lerman, Leonard S.

“…The melting behaviour of a DNA fragment carrying the mouse βmajglobin promoter was investigated as a means of establishing procedures for separating fragments…”
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Length-independent separation of DNA restriction fragments in two-dimensional gel electrophoresis by Fischer, S G, Lerman, L S

“…When double helical DNA is exposed to conditions favoring partial melting in polyacrylamide gels, its electrophoretic mobility undergoes a sharp cooperative…”
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A High-Resolution Annotated Physical Map of the Human Chromosome 13q12-13 Region Containing the Breast Cancer Susceptibility Locus BRCA2 by Fischer, Stuart G., Cayanis, Eftihia, Maria De Fatima Bonaldo, Bowcock, Anne M., Deaven, Larry L., Edelman, Isidore S., Gallardo, Theresa, Kalachikov, Sergei, Lawton, Lee, Longmire, J. L., Lovett, Michael, Osborne-Lawrence, Sherri, Rothstein, Rodney, Russo, James J., Soares, Marcelo Bento, Sunjevaric, Ivana, Venkatraj, V. S., Warburton, Dorothy, Zhang, Peisen, Efstratiadis, Argiris

“…Various types of physical mapping data were assembled by developing a set of computer programs (Integrated Mapping Package) to derive a detailed, annotated map…”
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Cell cycle changes in Physarum polycephalum histone H1 phosphate: relationship to deoxyribonucleic acid binding and chromosome condensation by Fischer, Stuart G, Laemmli, Ulrich K

“…We have examined the relationship of phosphate content in histone H1 of Physarum polycephalum to mitotic chromosome condensation and affinity for…”
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Positional Cloning of "Lisch-like", a Candidate Modifier of Susceptibility to Type 2 Diabetes in Mice: e1000137 by Dokmanovic-Chouinard, Marija, Chung, Wendy K, Chevre, Jean-Claude, Watson, Elizabeth, Yonan, Jason, Wiegand, Beebe, Bromberg, Yana, Wakae, Nao, Wright, Chris V, Overton, John, Ghosh, Sujoy, Sathe, Ganesh M, Ammala, Carina E, Brown, Kathleen K, Ito, Rokuro, LeDuc, Charles, Solomon, Keely, Fischer, Stuart G, Leibel, Rudolph L

“…In 404 Lepob/ob F2 progeny of a C57BL/6J (B6) x DBA/2J (DBA) intercross, we mapped a DBA-related quantitative trait locus (QTL) to distal Chr1 at 169.6 Mb,…”
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Electrophoresis: Theory, Techniques, and Biochemical and Chemical Applications, 2nd ed by Fischer, Stuart G.

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Regulatory activities of the 5'- and 3'-untranslated regions and promoter of the human aggrecan gene by Valhmu, W B, Palmer, G D, Dobson, J, Fischer, S G, Ratcliffe, A

“…Identification and characterization of the regulatory elements of the human aggrecan gene are necessary first steps in addressing the molecular mechanisms…”
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Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis by Myers, Richard M., Fischer, Stuart G., Lerman, Leonard S., Maniatis, Tom

“…Duplex DNA fragments differing by single base substitutions can be separated by electrophoresis in denaturing gradient polyacrylamide gels, but only…”
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Regulatory Activities of the 5′- and 3′-Untranslated Regions and Promoter of the Human Aggrecan Gene by Wilmot B. Valhmu, Glyn D. Palmer, Jennifer Dobson, Stuart G. Fischer, Anthony Ratcliffe

“…Identification and characterization of the regulatory elements of the human aggrecan gene are necessary first steps in addressing the molecular mechanisms…”
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Genomic Cloning and Chromosomal Assignment of the E2F Dimerization PartnerTFDPGene Family by Zhang, Yonghui, Venkatraj, Vijayanagaram S., Fischer, Stuart G., Warburton, Dorothy, Chellappan, Srikumar P.

“…TheTFDPgenes encode a family of transcription factors that can form heterodimers withE2Ffamily proteinsin vivo.The E2F–TFDP transcription factors are major…”
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Quantitative Polymerase Chain Reaction Assay for Aggrecan and Link Protein Gene Expression in Cartilage by Re, P., Valhmu, W.B., Vostrejs, M., Howell, D.S., Fischer, S.G., Ratcliffe, A.

“…A procedure has been developed to quantify the levels of aggrecan and link protein mRNAs in small amounts of various tissues, including cartilage, using the…”
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